13 citations
,
March 2021 in “British Journal of Pharmacology” This study found that KY19382 can effectively promote hair regeneration and follicle neogenesis in mice and human hair models by activating Wnt/β-catenin signalling, suggesting potential use for alopecia treatment.
13 citations
,
January 2021 in “Scientific Reports” This study found that Pannexin 3 plays a crucial role in skin development by regulating the transcription factor Epiprofin, affecting keratinocyte differentiation and hair follicle regeneration in mice.
13 citations
,
December 2012 in “Cells” This study describes how manipulating the actin cytoskeleton, particularly through the gelsolin family proteins, may enhance regenerative healing in mammals, suggesting potential therapeutic pathways for improved wound repair.
13 citations
,
June 2010 in “Journal of The American Academy of Dermatology” This study reports previously unreported nail features in Cronkhite-Canada syndrome, specifically recurrent onychomadesis of all 20 nails linked to systemic illness.
13 citations
,
May 2004 in “Dermatologic Surgery” This article outlines a method for achieving natural-looking hair direction and density in hair transplants using specific parting and incision techniques, without accelerating hair loss in the recipient area.
13 citations
,
December 2001 in “Dermatologic therapy” This review discusses the clinical presentations of alopecia areata, introduces guidelines for treatment studies, and explores potential changes in cutaneous innervation, but reports no new clinical results.
12 citations
,
April 2020 in “Facial Plastic Surgery Clinics of North America” This study reviews advancements in hair restoration surgery, noting that follicular unit excision significantly improves outcomes by enabling graft harvesting without scarring and reporting a graft transection rate under 4% when conducted with advanced equipment.
12 citations
,
May 2017 in “Pharmacology & therapeutics” This review discusses the mechanisms underlying immune tolerance failure in alopecia areata and highlights potential therapeutic avenues for restoring hair growth and achieving sustained remission, but reports no new clinical results.
12 citations
,
June 2009 in “Journal of Cosmetic Dermatology” This study reports the first cases of loose anagen hair syndrome in dark-skinned children from Upper Egypt, noting it may be under-diagnosed and primarily causes cosmetic concerns without affecting general health.
12 citations
,
January 1984 in “Clinics in Dermatology” This article discusses the decline in recognition and appropriate testing of syphilis by medical students due to limited clinical exposure and inconsistent education, with no new clinical results reported.
11 citations
,
July 2016 in “Current Opinion in Cell Biology” This review discusses stem cell behavior, highlighting their plasticity in tissue repair and the impact of somatic mutations on clonal expansion in early cancer, but reports no new experimental results.
11 citations
,
January 1998 in “Dermatology” This review explores various substances with potential antiandrogenic effects for treating acne, highlighting evidence for isotretinoin, and discusses the future consideration of 5 alpha-reductase inhibitors as antiandrogens.
10 citations
,
January 2024 in “Polymer Chemistry” This review discusses the design and advances of lipid–polymer hybrid nanoparticles as promising delivery systems for genome editing strategies, highlighting their potential in biomedical applications.
10 citations
,
October 2015 in “Medicina Clínica (english Edition)” This review discusses the therapeutic potential and safety of bioidentical recombinant human epidermal growth factor (rhEGF) for various skin and mucosa conditions and reports no new clinical results.
10 citations
,
February 2008 in “Photochemistry and photobiology” This study suggests that the vitamin D receptor and hairless gene may directly regulate each other via a transcriptional mechanism, potentially explaining phenotypic similarities between atrichia and VDRRIIa rickets.
9 citations
,
January 2011 in “EXPERIMENTAL ANIMALS” This study describes a novel hairless mutant rat strain, F344-Hr(krh), developed via ENU mutagenesis, which provides a model for skin disease and potentially focal glomerulosclerosis due to specific genetic mutations.
8 citations
,
May 2023 in “Cureus” In this case report, a 64-year-old woman developed alopecia areata after starting the IL-17A inhibitor secukinumab for psoriasis, highlighting a potential rare side effect of this treatment, with only three similar cases reported in the literature.
8 citations
,
February 2015 in “Cellular immunology” This study found that deleting Snai2 and Snai3 genes in mice disrupts immune cell development, resulting in severe autoimmunity and early death due to the loss of immune tolerance.
8 citations
,
August 2013 in “Pediatric Dermatology” This article reviews loose anagen hair syndrome, an inheritable hair disorder affecting children and sometimes adults, but does not report any new clinical results.
8 citations
,
November 2010 in “Facial Plastic Surgery” This review discusses the limitations and techniques of fat transfer for facial rejuvenation, focusing on achieving safe and long-term aesthetic outcomes without providing new clinical results.
8 citations
,
April 2010 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” This case report details the first pediatric occurrence of naevus trichilemmocysticus, a newly defined type of organoid naevus.
8 citations
,
December 2009 in “Journal of The European Academy of Dermatology and Venereology” This article discusses a novel mutation in the FERMT1 gene identified in a Spanish family with Kindler’s syndrome but reports no new clinical results.
8 citations
,
January 2003 in “Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy” This case report documents a cancer survivor who experienced cyclic alopecia areata following chemotherapy, suggesting potential autoimmune changes related to the treatment.
8 citations
,
June 2001 in “International Journal of Cosmetic Surgery and Aesthetic Dermatology” This article reviews methods for managing the donor area in hair restoration surgery to minimize scarring and reports no new results.
7 citations
,
January 2020 in “Journal of Dermatology” This study described specific skin and hair follicle abnormalities in three Japanese patients with Cantu syndrome, which may relate to the regulation role of SUR2 in hair follicle growth.
7 citations
,
November 2018 in “International Journal of Research -GRANTHAALAYAH” This study introduces a tabletop technique demonstrating that endogenous biomagnetic fields from human hair can induce red blood cells agglutination and Rouleaux formations.
7 citations
,
January 2018 in “Journal of Tissue Viability” This case report describes an 80-year-old patient whose scalp wound healed by secondary intention, with unexpected hair regrowth observed at 180 days, suggesting hair neogenesis is possible even in older adults.
7 citations
,
December 2016 in “British Journal of Dermatology” This report presents evidence that alopecia areata incognita may be a possible mechanism of hair loss in patients with Cronkhite–Canada syndrome.
7 citations
,
August 2016 in “Nursing for Women's Health” This article reviews the issue of hair-thread tourniquets in infants, emphasizing the importance of awareness for timely diagnosis and suggesting prevention strategies, but reports no new clinical results.
7 citations
,
June 2016 in “Bone Research” In this study, a Chinese Han family with hereditary vitamin D-resistant rickets was found to have a homozygous missense mutation in the VDR gene, and the affected individual uniquely responded well to treatment with oral calcium and low-dose calcitriol.