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Nonclassic congenital adrenal hyperplasia is a genetic disorder causing hormone imbalances, affecting fertility and requiring personalized treatment.

The document says PCOS is a common hormonal disorder in women, diagnosed by certain criteria, and managed with lifestyle changes and various medications.

The guideline refines PCOS diagnosis, promotes a healthy lifestyle, reviews treatments, and stresses long-term follow-up.

Women with PCOS have higher levels of AMH in their blood and follicles, and this can help predict their risk of overreaction to fertility treatments.

Ayurvedic treatment helped improve PCOD symptoms and ultrasound results.

Women with PCOS-related infertility can often conceive with treatments like clomiphene and metformin, but managing pregnancy complications is important.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

Rosiglitazone may be better than metformin for insulin resistance in PCOS, but more research is needed on certain biomarkers.

Molecular diagnostics help identify genetic defects causing endocrine diseases, improving diagnosis and treatment options.

Finasteride treats hair loss but may cause side effects like low libido and dizziness.

PCOS is a hormonal disorder causing symptoms like irregular periods and acne, and increases the risk of diabetes and heart disease.

Different treatments for PCOS focus on the specific symptoms, with weight loss and lifestyle changes being important.

Polycystic Ovary Syndrome (PCOS) affects 6%-15% of women of reproductive age, causing symptoms like acne and hair loss, and increasing the risk of type 2 diabetes and heart disease; it's managed through diet, exercise, and medications like Metformin and hormonal contraceptives.

The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

Metformin and thiazolidinediones are similarly effective for PCOS, but metformin is often preferred due to fewer side effects.

Eating less starch and dairy helped overweight women with PCOS lose weight and improve symptoms.

Over-the-counter products can help with menopause symptoms, but be aware of their ingredients.

Some plant-based treatments may help with ovary function, insulin resistance, and excess male hormones in PCOS, but more research is needed to confirm their safety and effectiveness.

The document concludes that managing hirsutism involves identifying the cause, using a scoring system for severity, combining cosmetic and medical treatments, encouraging weight loss, and providing psychological support, while noting the need for more research on drug treatments.

Women with nonclassic congenital adrenal hyperplasia experience more sexual dysfunction and distress.

More research is needed to understand how testosterone is maintained in adult males.

Dermatologists should customize cosmetic treatments for dark-skinned patients to minimize risks and complications.

Combining letrozole with metformin is the most effective treatment for inducing pregnancy in women with PCOS.

Premature ovarian insufficiency (POI) can harm women's sexual health, and they may benefit from hormone therapy and counseling.

Finasteride and dutasteride are effective in treating male hair loss but can cause sexual side effects and birth defects.

Women with regular menstrual cycles and PCOS have linked kisspeptin and LH hormone patterns, unlike those with irregular cycles.

Oral contraceptives can cause skin issues like dark patches, acne, yeast infections, sensitivity to light, spider veins, skin rashes, and hair loss.

The document concludes that careful history and physical exams are crucial for accurately diagnosing polycystic ovary syndrome and distinguishing it from other similar conditions.

Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

The foreword introduces a medical issue discussing male hormonal health, treatments, and the effects of conditions like obesity and aging.