12 citations,
June 2018 in “Journal of Cosmetic Dermatology” PRP is effective for hair loss and might work better with other treatments, but more research is needed.
9 citations,
April 2013 in “Dermatologic clinics” Some new treatments for children's skin conditions are effective, but risks must be weighed.
5 citations,
January 2017 in “Laboratory Animal Research” Gold thread implantation may help hair grow in humans and mice.
1 citations,
November 2023 in “BMC chemistry” Tadalafil and Finasteride may help treat aggressive melanoma.
May 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Topical Vorinostat shows promise for treating alopecia areata by promoting hair regrowth.
Caffeine can potentially treat common hair loss by counteracting hair follicle shrinkage caused by hormones.
Off-label drug use can be risky but sometimes beneficial when standard treatments fail.
46 citations,
January 2008 in “Climacteric” Testosterone therapy can help improve sexual desire and function in postmenopausal women but may cause side effects and is not FDA-approved for this use.
July 2023 in “International journal of biology, pharmacy and allied sciences” New medications are improving depression treatment, emphasizing accurate diagnosis and chronic care.
22 citations,
January 2018 in “European urology focus” New drugs and combination therapies are improving treatment for lower urinary tract symptoms.
22 citations,
March 2000 in “Clinics in Dermatology” Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.
28 citations,
January 2017 in “Critical Reviews in Therapeutic Drug Carrier Systems” Nanomaterials in biomedicine can improve treatments but may have risks like toxicity, needing more safety research.
4 citations,
May 2021 in “Journal of Cosmetic Dermatology” Botulinum toxin may help hair loss by increasing blood flow and reducing harmful factors.
3 citations,
January 2015 in “Social Science Research Network” The conclusion is that off-label drug use can lead to important medical discoveries and improve patient care.
26 citations,
February 2009 in “Drug Development Research” 17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.
2 citations,
April 2019 in “Journal of the American Society of Nephrology” Fluconazole might be a new treatment for a type of diabetes that affects water balance in the body.
13 citations,
January 2010 in “Advances in Biochemical Engineering / Biotechnology” Understanding hair biology is key to developing better treatments for hair and scalp issues.
40 citations,
January 2017 in “Journal of Dermatological Treatment” JAK inhibitors show promise for treating skin and hair disorders but need more research on long-term safety and effectiveness.
1 citations,
January 2017 in “Springer eBooks” Understanding the immune-related causes of Alopecia Areata has led to potential treatments like JAK inhibitors.
6 citations,
March 2022 in “Frontiers in drug discovery” Some small molecule antivirals show promise against COVID-19, but more research is needed to understand and improve them.
January 2020 in “Indian Journal of Pharmaceutical Sciences” The review discussed the use of rodent models to study hair loss and test traditional medicinal plants for promoting hair growth. It highlighted the limited number of FDA-approved treatments for hair loss, such as minoxidil and finasteride, and the potential of natural products to serve as leads for new therapies. The review emphasized the importance of understanding the mechanisms of action of various herbs and suggested that developing synthetic small molecules from herbal compounds could streamline the approval process. The paper also summarized the efficacy of different herbal preparations in promoting hair growth in rodent models and discussed the molecular pathways involved in hair growth modulation.
3 citations,
October 2021 in “Indian Journal of Plastic Surgery” Pattern hair loss (PHL) is the most common cause of hair loss in both men and women, accounting for 65% of consultations at hair referral centers. It is a hereditary, age-dependent condition characterized by progressive thinning of scalp hair, with distinct patterns varying by sex and age. The pathogenesis of PHL involves genetic factors, androgen metabolism, microbiomata, oxidative stress, and microinflammation. Despite numerous therapeutic molecules being patented, only two FDA-approved treatments—oral finasteride and topical minoxidil—are available, aimed at slowing hair thinning and increasing scalp coverage. The efficacy of antiandrogen treatments in women with normal androgen levels is questionable and poses health risks.
1 citations,
July 2017 in “Clinical research in dermatology” Hair loss, known as Androgenetic Alopecia, is often caused by hormones and can be diagnosed using noninvasive techniques. Treatments include topical minoxidil and oral finasteride, with new treatments being explored. There may also be a link between this type of hair loss and heart disease risk.
1 citations,
February 2017 in “MOJ bioequivalence & bioavailability” Treating hair loss effectively may require a multi-sided approach, using different treatments together, and topical treatments could be more effective and safer than oral ones.
6 citations,
May 2011 in “Journal of Pharmacy Technology” Old drugs can be used for new treatments, saving time and money, but there are challenges like needing more evidence and legal concerns.
September 2020 in “arXiv (Cornell University)” Some existing drugs and natural products might work against COVID-19 by targeting the virus's main protease.
70 citations,
July 2020 in “Pharmacological Reports” Cepharanthine, a Japanese hair loss drug, shows promise as a COVID-19 treatment but needs more testing.
11 citations,
July 2017 in “Expert Opinion on Investigational Drugs” New hair loss treatments may include topical medications, injections, and improved transplant methods.
4 citations,
January 2019 in “Elsevier eBooks” Finding new uses for existing drugs is promising and can lead to safer, more effective medicines.
11 citations,
October 2019 in “Cancers” Spironolactone may make some cancer treatments more effective by blocking a protein that helps cancer cells survive.