January 1986 in “Journal of Steroid Biochemistry” Lower testosterone levels in men may be linked to a higher risk of severe coronary artery disease.
September 1984 in “Journal of Biological Education” Human hair growth involves active, resting, and intermediate phases, and examining plucked hairs can teach students about hair biology and diseases.
November 1983 in “American Biology Teacher” Pattern baldness is likely caused by a dominant gene influenced by testosterone levels, making it more common in men.
April 1982 in “Journal of The American Academy of Dermatology” Retinoids help treat psoriasis effectively, but they can cause side effects and need more research on safe use with other treatments.
September 1961 in “Archives of Dermatology” Lichen sclerosus et atrophicus is generally not considered precancerous, but there are exceptions.
September 1961 in “Archives of Dermatology” Colchicine causes hair loss by damaging hair follicles.
January 1953 in “The Lancet” Cortisone may help hair regrow by altering the local environment, with regrowth starting 3-4 weeks after treatment, but its use is not widely recommended.
July 2021 in “Reactions Weekly” Man experienced lasting sexual dysfunction from finasteride, but malpractice claim was rejected.
November 2020 in “Reactions Weekly” Finasteride use linked to increased suicidality in patients under 45.
May 2019 in “Asian Journal of Chemistry” Finasteride forms three new products under acidic stress.
June 2018 in “International Review of Intellectual Property and Competition Law” June 2017 in “Journal of The American Academy of Dermatology” Microneedling with PRP and minoxidil (5%) improves hair growth more than minoxidil (5%) alone.
September 2016 in “Journal of Dermatological Science” The protein aPKCλ is crucial for keeping hair follicle stem cells inactive and for hair growth and regeneration.
September 1997 in “Journal of The European Academy of Dermatology and Venereology” New treatment improves male hair loss.
4809 citations,
January 2004 in “Fertility and Sterility” The 2003 consensus updated PCOS diagnosis criteria and highlighted increased risks of diabetes and heart disease for those affected.
4025 citations,
December 2003 in “Human Reproduction” The 2003 consensus updated PCOS diagnosis criteria and linked PCOS to higher risks of diabetes and heart problems, recommending lifestyle changes to lower these risks.
1540 citations,
October 2008 in “Fertility and Sterility” The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.
1533 citations,
October 2008 in “Endocrine reviews” Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.
1514 citations,
December 2011 in “Fertility and sterility” Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.
1415 citations,
October 2007 in “European Journal of Epidemiology” The Rotterdam Study investigates diseases in older adults and has produced many research findings.
1308 citations,
March 1998 in “Journal of bone and mineral research” The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.
1160 citations,
November 2018 in “Physiological Reviews” The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
883 citations,
August 2016 in “Nature Reviews Disease Primers” Polycystic Ovary Syndrome (PCOS) is a common condition in women that can cause metabolic, reproductive, and psychological issues, and requires lifestyle changes and medication for management.
855 citations,
June 2009 in “The Journal of Clinical Endocrinology & Metabolism” The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.
688 citations,
June 2007 in “Cell Stem Cell” Removing the ATR gene in adult mice causes rapid aging and stem cell loss.
658 citations,
June 2003 in “Endocrine reviews” Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.
610 citations,
April 2014 in “Nature Reviews Immunology” The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.
521 citations,
January 1954 in “Physiological Reviews” Hair growth is cyclic and influenced mainly by local factors.
506 citations,
January 2012 in “Molecular and Cellular Endocrinology” Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.
501 citations,
October 2008 in “Psychoneuroendocrinology” Hair cortisol levels can show increased stress during late pregnancy but only for up to six months.