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The guidelines recommend informed consent for gender-affirming treatments and stress the importance of personalized, culturally sensitive care for transgender individuals.

The report concludes that PCOS is mainly a condition of excess male hormones and its definition may change as new information is discovered.

Experts agree that PCOS affects women's health in complex ways, but more research is needed to understand and treat it effectively.

While PCOS might increase the risk of heart disease, there's not strong evidence to prove it causes earlier heart problems.

The bulletin provides guidelines for diagnosing and managing PCOS, suggesting weight loss, hormonal contraceptives, and diabetes screening, with clomiphene for infertility and various treatments for excess hair.

The Rotterdam Study aims to understand various diseases in older adults.

Modulating BMP activity changes the number, size, shape, and type of ectodermal organs.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

Janus kinase inhibitors are promising drugs for treating autoimmune and inflammatory diseases.

Brain hormones significantly affect hair color and could potentially be used to prevent or reverse grey hair.

Women with PCOS are more likely to have sleep apnea, mainly if they are obese.

Metformin has limited effectiveness for improving PCOS symptoms and lacks clear benefits, needing more research to confirm its efficacy.

Understanding how melanocyte stem cells work could lead to new treatments for hair graying and skin pigmentation disorders.

Some alternative treatments for hair loss might work, but more research is needed.

Bariatric surgery may help severely obese teenagers but has risks and requires careful patient selection and long-term care.

Thyroid hormones are important for skin health and changes in them can affect conditions like hair loss and eczema.

Women with PCOS have unhealthy changes in their cholesterol particles that are not related to their body weight.

Mesotherapy might help reduce fat in specific areas for those close to their ideal weight, but more research and care are needed to ensure safety.

The 2018 update to the ED care model added a new severity score and stressed a detailed evaluation of both physical and psychological aspects.

Understanding how epigenetic regulation affects stem cells is key to cancer insights and new treatments.

Eating less can slow aging and help keep stem cells healthy by cleaning out damaged cell parts.

An imbalance in gut bacteria is linked to skin immune diseases and may affect their outcomes and related health issues.

Birth control pills can help reduce mild to moderate acne in women.

Many infertile women with PCOS in Central Vietnam have metabolic or insulin resistance syndrome, with obesity and older age increasing the risk.

Acne is caused by multiple factors including oil production, bacteria, inflammation, and possibly diet and environment.

The critique suggests that Wilton's work unintentionally supports the very stereotypes it aims to question and calls for a broader, more inclusive approach to understanding gender.

Topical L-thyroxine may help with wound healing and hair growth but should be used short-term due to potential risks.

Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.