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Obesity can worsen wound healing by negatively affecting the function of stem cells in fat tissue.

Older people tend to have higher biotin levels, which are weakly linked to certain blood components and negatively linked to triglycerides; biotin should be checked in patients with high triglycerides or medication-related skin issues, and only supplemented if deficient. Vitamin D and folate deficiencies are linked to specific skin conditions.

The document concludes that inflammation markers can be used in diabetes, vitamin D3 affects immune pathways, hyperthyroidism changes hormone levels, androgen levels help diagnose Adrenocortical Carcinoma, erectile dysfunction is linked to diabetes, hypogonadism is common in HIV-infected males, and hormones can be biomarkers for various conditions.

Some existing medicines show promise as safe treatments to protect against the side effects of radiation therapy.

Acne is caused by increased sebum, abnormal skin shedding, bacteria, and inflammation, not dirt; treatments vary from creams to antibiotics or isotretinoin, with severe cases needing a dermatologist's care.

Insulin resistance in women with PCOS can lead to serious health issues, but lifestyle changes and certain medications can help manage symptoms.

Birth control pills can help manage acne, but dermatologists should know their skin-related side effects, especially when prescribing drugs that can harm unborn babies.

The document concludes that PCOS is a complex disorder caused by both genetic and environmental factors, affecting women's health in various ways, and requires personalized treatment.

The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.

Systemic retinoids are effective for psoriasis but have side effects; benefits may outweigh risks, especially when reducing cancer risks from other treatments.

Skin diseases linked to insulin resistance should be managed to prevent diabetes and reduce heart disease risk.

The document concludes that managing PCOS involves treating symptoms and reducing long-term metabolic risks, with lifestyle changes being important.

Lifestyle changes and clomiphene are first-line treatments for infertility in women with PCOS, with other options available if these fail.

MendelVar is a tool that helps identify important genes by combining GWAS data with Mendelian disease information.

The document explains the genetic causes and characteristics of inherited hair disorders.

Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.

Any drug can cause skin reactions, but antibiotics, NSAIDs, and psychotropic drugs are more common, with some reactions being life-threatening.

Losing weight and eating better are key to managing metabolic syndrome and its related conditions.

The document concludes that Syndromes of Severe Insulin Resistance are rare disorders with limited treatment options.

Psoriasis treatments range from topical creams to systemic medications with serious side effects, and while treatments can manage symptoms, there is no cure.

Some skin conditions may increase the risk of heart disease, but are not yet included in cardiovascular prevention guidelines.

The conclusion is that lifestyle changes and weight loss are first-line treatments for infertility due to anovulation, with various medications and assisted reproductive technologies as additional options.

The document concludes that respectful, gender-affirming healthcare improves mental health and encourages continued medical care for transgender and non-binary individuals.

The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.

Male pattern baldness is not a risk factor for heart disease based on cholesterol levels alone.

Alopecia areata, a common autoimmune hair loss condition, often runs in families.

Most patients with Porphyria Cutanea Tarda had skin blisters and were often affected by hepatitis C and alcohol abuse, with differences between familial and sporadic cases.

Familial frontal fibrosing alopecia affects premenopausal women too, and early diagnosis is important, but no proven medication exists yet.

Some families have a genetic condition where they are born with irregular scalp defects.

Eruptive vellus hair cysts can run in families.