3 citations,
October 2019 in “CRC Press eBooks” Isotretinoin effectively treats severe acne but can cause significant side effects like dry skin and hair loss.
16 citations,
November 2019 in “Journal of biological chemistry/The Journal of biological chemistry” Mice without certain skin enzymes have faster hair growth and bigger eye glands.
29 citations,
November 2011 in “Veterinary pathology” The study found that mouse sweat glands develop before birth, mature after birth, and have specific keratin patterns.
28 citations,
November 2013 in “Cornea” Scientists have made progress in creating replacement teeth, hair, and glands that work, which could lead to new treatments for missing teeth, baldness, and dryness conditions.
March 2024 in “International journal of molecular sciences” Meibomian glands are highly specialized and differ significantly from other sebaceous glands in structure and function.
May 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Primary cilia affect the size and oil production of eye glands but not the oil's makeup.
December 2009 in “Saengmyeong gwahag hoeji/Saengmyeong gwahak hoeji” Thymosin β4 and VEGF are important for blood vessel formation in many organs.
26 citations,
August 2018 in “The journal of immunology/The Journal of immunology” AIRE-deficient rats developed severe autoimmune disease similar to APECED, useful for testing treatments.
9 citations,
April 2022 in “Journal of radiation research” Boron neutron capture therapy for head and neck cancer can cause side effects like mouth sores and skin irritation, which vary depending on where the treatment is aimed.
3 citations,
December 2020 The interdigital gland in crossbred sheep is similar to skin and has specialized structures for secretion.
8 citations,
February 2010 in “Journal of Dermatology” A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.
2 citations,
November 2022 in “Veterinary sciences” The interdigital gland of Vembur sheep shows sex-based differences in size and chemical makeup, possibly affecting communication and disease protection.
8 citations,
January 1996 in “Springer eBooks” Male pattern baldness may be caused by factors like poor blood circulation, scalp tension, stress, and hormonal imbalances, but the exact causes are still unclear.
August 2023 in “Malaysian Journal of Medicine and Health Sciences/Malaysian journal of medicine and health sciences” Pueraria mirifica extract may help treat benign prostatic hyperplasia.
86 citations,
July 1993 in “Drugs” Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.
44 citations,
December 1991 in “Annals of the New York Academy of Sciences” EGF and FGF help hair growth by affecting cell differentiation and fiber growth.
21 citations,
May 2020 in “General and Comparative Endocrinology” Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.
10 citations,
January 1985 in “Elsevier eBooks” Active oxygen species might be involved in skin tumor growth, but their exact role is unclear.
17 citations,
January 2020 in “The World Journal of Men's Health” The document highlighted significant health risks associated with long-term use of finasteride and dutasteride, commonly prescribed for benign prostatic hyperplasia (BPH) and androgenetic alopecia (AGA). These drugs induced a novel form of androgen deficiency, leading to various metabolic dysfunctions such as non-alcoholic fatty liver disease (NAFLD), insulin resistance (IR), type 2 diabetes mellitus (T2DM), dry eye disease, and potential kidney dysfunction. Studies in both animal models and human subjects indicated liver lipid accumulation, impaired glucose disposal, and increased risk of T2DM. A cohort study of 230 men treated with dutasteride for 36-42 months showed increased blood glucose, cholesterol levels, and liver enzyme activities. The review called for heightened awareness of these potential adverse effects and reconsideration of prolonged use of these medications.
759 citations,
February 2009 in “Current Biology” Hair follicles are complex, dynamic mini-organs that help us understand cell growth, death, migration, and differentiation, as well as tissue regeneration and tumor biology.
9 citations,
December 2017 in “Molecular Medicine Reports” Finasteride causes reduced tear flow and severe eye inflammation.
11 citations,
April 2013 in “Ocular Surface” The document concludes that modern ocular cosmetics enhance beauty and eyelash health, with safe practices and regulations being important.
3 citations,
May 2011 in “Practice nursing” As skin ages, it gets thinner, paler, and more wrinkled, and protection and care like sunblock and moisturizers are important.
14 citations,
October 2018 in “PloS one” Deleting the Far2 gene in mice causes sebaceous gland issues and patchy hair loss.
13 citations,
January 2021 in “Dermatologic Therapy” Sebaceous glands in our skin, developing during pregnancy and active in puberty, produce sebum for skin lubrication, temperature control, and fighting germs, also help in hormone regulation, and their dysfunction can cause conditions like acne and hair loss.
Benign skin tumors need accurate diagnosis to ensure proper treatment.
788 citations,
February 2007 in “Nature” The document concludes that skin stem cells are important for hair growth and wound healing, and could be used in regenerative medicine.
Dermatoscopy and videodermatoscopy are useful for diagnosing and monitoring various skin, hair, and nail conditions.
86 citations,
December 2001 in “Experimental dermatology” Mutant mice help researchers understand hair growth and related genetic factors.
Inhibiting AP-1 changes skin tumor types and affects tumor cell identity.