research Live-Imaging the Interface Between Homeostasis and Cancer Initiation
Mutant cells in hair follicles are influenced by their location and interactions with surrounding cells.
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research Whole-Genome SNP Genotyping Mapped a Novel Locus for Hereditary Hypotrichosis on Chromosome 2q31.1–q32.2
Researchers found a new area on chromosome 2 linked to a genetic hair loss condition.
research Healthy Hair: Form and Function
Hair health is influenced by genetics, aging, and environmental factors, with proper care needed to maintain it.
research Alopecias
The document concludes that non-scarring alopecias can be reversed, but scarring alopecias cause permanent hair loss.
research Phenobarbital
A woman experienced unusual hair loss and skin reactions after taking phenobarbital, but her hair grew back after treatment.
research A Synonymous Polymorphism of APCDD1 Affects Translation Efficacy and Is Associated with Androgenic Alopecia
A specific gene change in APCDD1 increases the risk of hair loss.
research A Mouse with Bad Hair and Poor Taste
A defective gene causes hair loss and taste insensitivity in BTBR mice.
research Role of Polymorphism of the Androgen Receptor Gene and Non-Random X Chromosome Inactivation in the Pathogenesis of Androgenic Alopecia
Certain genes and X chromosome patterns may significantly contribute to the development of hair loss.
research Hair Sciences: The Hair Cycle Discussed with Dr. Gilliam Westgate
Androgens affect hair growth and shedding, with genetic and non-genetic factors influencing baldness.
research Geographical Differences in Male Infertility Between the United States and Canada: Insights From the Andrology Research Consortium
American men are older, more obese, and have longer infertility than Canadian men.
research Characteristics of Finasteride Users in Comparison with Nonusers: A Nordic Nationwide Study Based on Individual-Level Data from Denmark, Finland, and Sweden
Finasteride users have higher odds of certain health issues and lower odds of specific lifestyle factors compared to nonusers.
research Early-Onset Androgenetic Alopecia and Endocrine Disruptors
Endocrine disruptors may cause early hair loss.
research Mutations in Three Genes Encoding Proteins Involved in Hair Shaft Formation Cause Uncombable Hair Syndrome
Mutations in three genes cause Uncombable Hair Syndrome, leading to frizzy hair that can't be combed flat.
research Bi-Allelic Mutations in LSS, Encoding Lanosterol Synthase, Cause Autosomal-Recessive Hypotrichosis Simplex
Mutations in the LSS gene cause a rare type of hereditary hair loss.
research De Novo Single-Nucleotide and Copy Number Variation in Discordant Monozygotic Twins Reveals Disease-Related Genes
The research found genetic differences in identical twins that could explain why one twin has a disease while the other does not.
research Biotin and Acetazolamide for Treatment of an Unusual Child With Autism Plus Lack of Nail and Hair Growth
Biotin and acetazolamide improved hair and nail growth, mental function, and reduced headaches in a child with autism.
research Proliferative, Lymphocytic, Infundibular Mural Folliculitis and Dermatitis with Prominent Follicular Apoptosis and Parakeratotic Casts in Four Labrador Retrievers: Preliminary Description and Response to Therapy
A new skin disease in four Labrador retrievers responded well to immunosuppressive treatment.
research Shortcutting the Diagnostic Odyssey: The Multidisciplinary Program for Undiagnosed Rare Diseases in Adults (UD-PrOZA)
The UD-PrOZA program successfully diagnosed 18% of adult patients with rare diseases, often using genetic testing.
research PLCD1 and Pilar Cysts
The research linked PLCD1 gene variants to the development of trichilemmal cysts.
research A Homozygous Missense Variant in K25 Underlying Overlapping Phenotype With Woolly Hair and Dental Anomalies
A specific mutation in the K25 gene causes a rare genetic disorder with curly hair at birth and later hair loss, along with dental issues.
research A Retrospective Review of Hyperaesthetic Leucotrichia in Horses in the USA
Hyperaesthetic leucotrichia in horses causes painful, recurring skin lesions and hair color changes, especially in Arabian and American paint horses.
research ELife Assessment: CaBP1 and 2 Enable Sustained CaV1.3 Calcium Currents and Synaptic Transmission in Inner Hair Cells
CaBP1 and 2 are important for maintaining the activity of calcium channels necessary for hearing in inner ear cells.
research Ubiquitomics of CYLD-Deficient Skin Tumors Reveals Dysregulation of Hair Follicle Keratinocyte Processes
CYLD deficiency in skin tumors disrupts hair follicle cell processes and protein secretion.
research Twins With Psychiatric Features and a Nonsense HRAS Variant Affecting Transcript Processing
A new HRAS gene variant may cause a range of symptoms including intellectual disability and psychiatric issues.
research A Brazilian Case of IFAP Syndrome With Severe Congenital Ichthyosis and Limb Malformations Caused by a Rare Variant in MBTPS2
A Brazilian male with IFAP syndrome has a unique genetic variant causing his condition.
research Uncombable Hair Syndrome Due to Maternal Uniparental Disomy of Chromosome 1
A person got uncombable hair syndrome from two copies of chromosome 1 from their mother.
research Novel Biallelic RIPK4 Mutations Cause Ectodermal Dysplasia with Cutaneous Syndactyly
New RIPK4 gene mutations were found to cause a type of skin and limb birth defect.
research News in Brief
Researchers discovered potential origins and new treatments for skin cancer, including biomarkers for melanoma and therapies that reduce tumor growth.
research Histopathological and Topical Immunological Changes in Alopecia
Autoimmune and inflammatory processes are involved in both scarring and non-scarring types of hair loss.
research Advances in Stem Cell-Based Therapy for Hair Loss
Stem cell therapies show promise for treating hair loss, but more research is needed to understand their safety and effectiveness.