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Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.

Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.

Compound 15a was effective in inhibiting 5α-reductase.

Method accurately measures finasteride and tamsulosin in combined drug form.

Pfizer found that pantolactam-based compounds can reduce sebum (skin oil) production when applied topically.

The best mix for a hair loss treatment cream is 10% Sophora japonica tincture and 5% Serenoa repens extract.

Flutamide caused damage to male rat reproductive organs and may affect fertility.

The document concludes that scientists created various steroids with different properties, including a more effective semi-synthetic vitamin D.

The vitamin D receptor is crucial for bone health and affects various body systems, with mutations potentially leading to disease.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

New nanofiber technology improves wound healing by supporting cell growth and delivering treatments directly to the wound.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

The document concludes that developing generic topical drugs requires ensuring they match the original in quality, composition, and structure, and often involves complex testing and regulatory steps.

Pectin biosynthesis is essential for the growth of cotton fibers and Arabidopsis root hairs.

Nanoparticles can improve skin drug delivery but have challenges like toxicity and stability that need more research.

Mouse hair follicle cells briefly grow during the early hair growth phase, showing that these cells are important for starting the hair cycle.

Minoxidil-loaded NLC gel shows potential for effective alopecia treatment.

Hair elemental analysis could be useful for health and exposure assessment but requires more standardization and research.

Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

Men's thigh hair grows longer and has a longer growth cycle than women's, but arm hair growth is similar between genders.

A deficiency in the TTC7A gene causes immune problems, gut issues, and hair loss.

Nanocarrier-loaded gels improve drug delivery for cancer, skin conditions, and hair loss.

Some women with acne have higher levels of free testosterone, which might suggest using hormonal treatments for acne.

Using minoxidil on the scalp can help grow hair for people with hereditary baldness.

The new dutasteride formula can be applied to the skin, may promote hair growth, and has fewer side effects.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.