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    Did you mean Estrogen Receptor Alpha?
    Glossary Estrogen Receptor Alpha

    protein inside cells that binds to estrogen hormone

    Estrogen Receptor Alpha (ERα) is a protein found inside cells that binds to the hormone estrogen. This receptor is crucial for regulating various biological processes, including reproductive functions and the development of certain tissues. In the context of hair and alopecia, ERα can influence hair growth and loss, as estrogen plays a role in the hair growth cycle.

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    1. The Modulation of Aromatase and Estrogen Receptor Alpha in Cultured Human Dermal Papilla Cells by Dexamethasone: A Novel Mechanism for Selective Action of Estrogen via Estrogen Receptor Beta? Journal of Investigative Dermatology · 2006 · 65 citations
    2. Minoxidil May be a Partial Agonist of Estrogen Receptor Alpha microPublication · 2026
    3. Ferulic acid promotes hair growth via estrogen receptor alpha activation in cultured human dermal papilla cells Scientific Reports · 2026
    4. Reproduction of the human relevant potency threshold (HRPT) for estrogen receptor alpha agonism in an inference performance screen for ICCVAM’s regulatory scientific confidence framework Frontiers in Toxicology · 2025
    5. Hair Cycle Control by Estrogens: Catagen Induction via Estrogen Receptor (ER)-α Is Checked by ERβ Signaling Endocrinology · 2005 · 92 citations
    6. Early androgen activity after birth determines the hypothalamic expression of androgen and estrogen receptors in adulthood in female but not in male rats Reproductive Biology and Endocrinology · 2025
    7. Complex Extract of Polygonatum sibiricum and Nelumbinis semen Improves Menopause Symptoms via Regulation of Estrogen Receptor Beta in an Ovariectomized Rat Model Nutrients · 2023
    8. Selected variants of the steroid-5-alpha-reductase isoforms SRD5A1 and SRD5A2 and the sex steroid hormone receptors ESR1, ESR2 and PGR: No association with female pattern hair loss identified Experimental Dermatology · 2012 · 18 citations
    9. Pharmacological activation of estrogen receptors-α and -β differentially modulates keratinocyte differentiation with functional impact on wound healing International Journal of Molecular Medicine · 2015 · 23 citations
    10. An estrogen receptor pathway regulates the telogen-anagen hair follicle transition and influences epidermal cell proliferation. Proceedings of the National Academy of Sciences of the United States of America · 1996 · 154 citations
    11. 17β-Estradiol and ICI-182780 regulate the hair follicle cycle in mice through an estrogen receptor-α pathway 2000 · 71 citations
    12. 17β-Estradiol Inhibits Wound Healing in Male Mice via Estrogen Receptor-α American Journal Of Pathology · 2010 · 38 citations
    13. Role of estrogen receptor signaling in the control of the hair follicle cycle 2004
    14. Estrogen and androgen signaling in the pathogenesis of BPH Nature reviews. Urology · 2011 · 149 citations
    15. Localization of sex steroid receptors in human skin. PubMed · 2004 · 147 citations
    16. Sex Steroid Hormone Receptors in Human Skin Appendage and its Neoplasms Endocrine Journal · 2005 · 59 citations
    17. Triclocarban, Triclosan, Bromochlorophene, Chlorophene, and Climbazole Effects on Nuclear Receptors: An <i>in Silico</i> and <i>in Vitro</i> Study Environmental health perspectives · 2020 · 29 citations
    18. Current evidence for the involvement of sex steroid receptors and sex hormones in benign prostatic hyperplasia Research and Reports in Urology · 2019 · 26 citations
    19. Estrogen-Dependent Ontogeny of Sex Differences in Somatostatin Neurons of the Hypothalamic Periventricular Nucleus* Endocrinology · 1998 · 19 citations
    20. Ovarian sex steroid receptors and sex hormones in androgenized rats Reproduction · 2016 · 13 citations
    21. The premature catagen induced by estrogen was accompanied with advance apoptosis of precortex cells. OPAL (Open@LaTrobe) (La Trobe University) · 2015
    22. 202 Activation of breast cancer cell proliferation by ROR-alpha through aromatase promoter Ejc Supplements · 2010
    23. The Distribution of Estrogen Receptor β Is Distinct to That of Estrogen Receptor α and the Androgen Receptor in Human Skin and the Pilosebaceous Unit Journal of Investigative Dermatology Symposium Proceedings · 2003 · 130 citations
    24. Melatonin and the hair follicle Journal of pineal research · 2007 · 109 citations
    25. Endocrinology of the Aging Prostate: Current Concepts Frontiers in Endocrinology · 2021 · 21 citations
    26. A Hair Growth-Promoting Effect of Chinese Black Tea Extract in Mice Bioscience, Biotechnology, and Biochemistry · 2013 · 3 citations
    27. The postnatal offspring of finasteride-treated male rats show altered ERα and PCNA expression in the liver Reproductive Biology · 2025
    28. Dihydrotestosterone Induces Arterial Stiffening in Female Mice Research Square (Research Square) · 2023
    29. Endocrine control of benign prostatic hyperplasia Andrology · 2016 · 97 citations
    30. 5α‐Reductase Isozymes and Androgen Actions in the Prostate Annals of the New York Academy of Sciences · 2009 · 93 citations