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KLF4 is important for maintaining skin stem cells and helps heal wounds.

Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.

Fadrozole and finasteride change gene expression related to sex hormones and thyroid hormones in frog larvae development.

Beard and scalp hair cells have different gene expressions, which may affect beard growth characteristics.

The mineralocorticoid receptor may play a role in skin and hair health and could be a new target for treating related disorders.

Using a gene therapy with the Sonic Hedgehog gene helps mice regrow hair faster after losing it from chemotherapy.

DHT stops hair regrowth in mice, similar to human hair loss.

African American men with prostate cancer have more androgen receptor mutations, which may lead to more aggressive cancer compared to Caucasian American men.

The vitamin D receptor is involved in multiple body functions beyond calcium regulation, including immune response and rapid reactions not related to gene activity.

Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.

Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.

Men with hair loss have more DNA changes in back-of-head hair follicles, possibly protecting them from thinning.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

SA linked to mitochondrial issues and oxidative stress, while AGA involves disrupted hair growth genes.

Estrogen and androgenic hair increase melanoma risk, especially in European-ancestry individuals.

Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.

The protein StAR is found in 17 different organs and can affect hair loss and brain functions, but its full role is not yet fully understood.

Testosterone reduces key molecules needed for early pregnancy in rats.

The vitamin D receptor has many roles in the body beyond managing calcium, affecting the immune system, hair growth, muscles, fat, bone marrow, and cancer cells.

Allopregnanolone increases growth and changes gene activity in human brain cancer cells.

Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.

NAC1 controls certain enzymes that reduce root hair growth in Arabidopsis.

GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

OCT binds strongly to hair sheath cells and may affect skin and hair growth with fewer side effects than vitamin D3.

Estrogen increases blood vessel growth factor production, while testosterone blocks this increase.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Estrogen loss during menopause worsens skin health, but hormone replacement therapy may improve it, though more research is needed.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.