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    Did you mean Estrogen Receptor Antagonist?
    Glossary Estrogen Receptor Antagonist

    blocks estrogen from activating its cellular receptors

    An Estrogen Receptor Antagonist, also known as an Estrogen Blocker or ER Antagonist, is a substance that binds to estrogen receptors on cells and prevents estrogen from exerting its effects. This can be useful in treating conditions like hormone-sensitive cancers, such as certain types of breast cancer, by inhibiting the growth-promoting effects of estrogen on these cancer cells.

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    Research 30 of 1000+

    1. On the Effect of Estrogen Receptor Agonists and Antagonists on the Mouse Hair Follicle Cycle Journal of Investigative Dermatology · 1998 · 11 citations
    2. Failure of Topical Estrogen Receptor Agonists and Antagonists to Alter Murine Hair Follicle Cycling Journal of Investigative Dermatology · 1998 · 8 citations
    3. Minoxidil May be a Partial Agonist of Estrogen Receptor Alpha microPublication · 2026
    4. Pharmacological activation of estrogen receptors-α and -β differentially modulates keratinocyte differentiation with functional impact on wound healing International Journal of Molecular Medicine · 2015 · 23 citations
    5. Estrogen Receptor α, but not Estrogen Receptor β, is Involved in the Regulation of the Hair Follicle Cycling as well as the Thickness of Epidermis in Male Mice Journal of Investigative Dermatology · 2002 · 72 citations
    6. 25 years of ERβ: a personal journey Journal of molecular endocrinology · 2021 · 11 citations
    7. Гормональный дисбаланс как фактор развития хронического простатита: механизмы и перспективы терапии Репродуктивное здоровье Восточная Европа · 2025
    8. Clinical Snippets Journal of Investigative Dermatology · 2004
    9. Steroid Hormones Elsevier eBooks · 2016 · 3 citations
    10. Hair Cycle Control by Estrogens: Catagen Induction via Estrogen Receptor (ER)-α Is Checked by ERβ Signaling Endocrinology · 2005 · 92 citations
    11. The GPR30 agonist G-1 promotes hair growth via Wnt/Hedgehog signaling in mice Frontiers in Pharmacology · 2025
    12. Triclocarban, Triclosan, Bromochlorophene, Chlorophene, and Climbazole Effects on Nuclear Receptors: An <i>in Silico</i> and <i>in Vitro</i> Study Environmental health perspectives · 2020 · 29 citations
    13. Glucocorticoid and Sex Hormone Receptors: Clinical Implications and Therapeutic Relevance Dermatologic Clinics · 2007 · 4 citations
    14. Anti-SARS-CoV-2 Action of 5α-Reductase Inhibitors May Be Mediated by Dehydroepiandrosterone. Letter. The Journal of Urology · 2022 · 1 citations
    15. Association of estrogen receptor gene variants (ESR1 and ESR2) with polycystic ovary syndrome in Tunisia Gene · 2020 · 9 citations
    16. Polymorphisms of the Androgen Receptor Gene and the Estrogen Receptor β Gene Are Associated with Androgen Levels in Women1 The Journal of Clinical Endocrinology and Metabolism · 2001 · 93 citations
    17. Ferulic acid promotes hair growth via estrogen receptor alpha activation in cultured human dermal papilla cells Scientific Reports · 2026
    18. Effect of estrogens on skin aging and the potential role of selective estrogen receptor modulators Climacteric · 2007 · 67 citations
    19. Androgen Receptor Ligands: Agonists and Antagonists Elsevier eBooks · 2017 · 2 citations
    20. Patient-Reported Outcomes From Phase III Neoadjuvant Systemic Trial Comparing Neoadjuvant Chemotherapy With Neoadjuvant Endocrine Therapy in Pre-Menopausal Patients With Estrogen Receptor-Positive and HER2-Negative, Lymph Node-Positive Breast Cancer Frontiers in Oncology · 2021 · 1 citations
    21. Vitamin D and androgen receptor-targeted therapy for triple-negative breast cancer Breast Cancer Research and Treatment · 2016 · 59 citations
    22. Reproduction of the human relevant potency threshold (HRPT) for estrogen receptor alpha agonism in an inference performance screen for ICCVAM’s regulatory scientific confidence framework Frontiers in Toxicology · 2025
    23. 17β-Estradiol Inhibits Wound Healing in Male Mice via Estrogen Receptor-α American Journal Of Pathology · 2010 · 38 citations
    24. A role of melatonin in neuroectodermal‐mesodermal interactions: the hair follicle synthesizes melatonin and expresses functional melatonin receptors ˜The œFASEB journal · 2005 · 122 citations
    25. The role of nuclear hormone receptors in cutaneous wound repair Cell Biochemistry and Function · 2014 · 68 citations
    26. Recent discoveries and developments of androgen receptor based therapy for prostate cancer MedChemComm · 2015 · 17 citations
    27. The Modulation of Aromatase and Estrogen Receptor Alpha in Cultured Human Dermal Papilla Cells by Dexamethasone: A Novel Mechanism for Selective Action of Estrogen via Estrogen Receptor Beta? Journal of Investigative Dermatology · 2006 · 65 citations
    28. Complex Extract of Polygonatum sibiricum and Nelumbinis semen Improves Menopause Symptoms via Regulation of Estrogen Receptor Beta in an Ovariectomized Rat Model Nutrients · 2023
    29. Testosterone protects female embryonic heart H9c2 cells against severe metabolic stress by activating estrogen receptors and up-regulating IES SUR2B The International Journal of Biochemistry & Cell Biology · 2012 · 24 citations
    30. Organizational Effects of Estrogens and Androgens on Estrogen and Androgen Receptor Expression in Pituitary and Adrenal Glands in Adult Male and Female Rats Frontiers in Neuroanatomy · 2022 · 1 citations