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Hormone therapy is essential for transgender individuals but requires careful management due to possible metabolic effects.

Most youth with gender dysphoria received hormones, had minor complications, and showed a decrease in suicide attempts after treatment.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.

5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.

Sex hormones, especially androgens, play a key role in causing acne.

Finasteride reduces hairiness and androgen levels in women with unexplained excessive hair growth.

Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.

Red ginseng may improve immunity, fatigue, memory, blood circulation, and menopausal symptoms, and is generally safe to consume.

Fulvestrant is a well-tolerated new treatment for advanced breast cancer that may delay chemotherapy.

Pregnancy often causes skin changes like darkening, stretch marks, and hair growth, which may improve after childbirth.

Oral contraceptives help treat hyperandrogenic disorders, improving symptoms like excessive hair and acne.

17β-estradiol can reduce inflammation in the skin.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

Hair loss in women may have causes other than hormones.

Frontal fibrosing alopecia mainly affects postmenopausal women and may be linked to thyroid hormones.

Current murine models need improvement for better human wound healing research translation.

Mouse genital development depends on male or female hormones for specific features.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

Gonadal dysgenesis, like Turner's and Klinefelter's syndromes, negatively affects bone health, but hormone treatments can help.

Menopause significantly reduces skin collagen, leading to thinner, less elastic skin, and hormone replacement may help but requires careful consideration.

Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.

Hormone therapy and surgeries for transgender individuals affect their skin and hair, requiring specific dermatologic treatments and respectful care.

The document concludes that identifying the cause of amenorrhea is crucial for proper treatment.

The document concludes that treating PCOS requires a combination of drugs to manage reproductive and metabolic symptoms, with more research needed on combination therapies.

A male with aromatase deficiency improved bone health with estradiol treatment.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

Aromatase inhibitor therapy for breast cancer increases the risk of hair loss and thinning.