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Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Cyproterone acetate-estrogen most effective for hirsutism, but consider side effects and patient needs.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.

Dietary changes, including weight loss and a balanced diet, are important for managing PCOS, especially in overweight women.

Most pregnant women experience skin darkening and hair changes, with these effects usually going away after giving birth.

Menopause-related hormonal changes affect hair but are not the only cause of hair changes in middle-aged women.

Hair growth slows and shedding increases after childbirth, but most women don't experience excessive hair loss.

Menopausal women have higher androgen levels, which can cause symptoms like facial hair growth and low sexual desire.

Activating ER-β, not ER-α, improves skin cell growth and wound healing.

All treatments reduce hair growth; low dose flutamide most effective with fewer side effects.

Topical estrogen helps hair growth in menopausal women with no major side effects.

Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.

The new FDA labeling rules provide more detailed drug safety information for pregnant and breastfeeding women, but more data is needed on the risks of many dermatologic drugs.

Estrogen and androgenic hair increase melanoma risk, especially in European-ancestry individuals.

Using 5-alpha reductase inhibitors may lower the risk of breast cancer in females.

Some drugs can cause reversible hair loss, but certain chemotherapy drugs may lead to permanent hair loss; drugs can also change hair color and texture.

PCOS may be influenced by factors in the blood, not just the ovaries.

Estrogen increases a growth factor in hair cells which might affect hair loss.

A postmenopausal woman's facial redness, acne, and excess hair were caused by too much hormone therapy for insomnia, but improved after stopping the treatment.

Pregnancy can cause skin darkening, varicose veins, more sweating, hair growth, hair loss after birth, nail changes, and gum inflammation.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

Aging causes changes in the scalp that can affect hair growth and lead to older-looking hair in women.

Troxerutin helps protect skin cells from oxidative stress and may be good for treating hair loss.

Sleep, testosterone levels, and a specific enzyme activity affect skin oil production in women.

Biotin helps regulate proteins in the blood, which may explain its role in hair growth.

Gut flora changes could potentially indicate depression, but more research is needed.

Aging-related hormone changes affect voice quality, especially during puberty, menstruation, pregnancy, and menopause.

Finasteride and CPA-EE2 equally reduce hirsutism, but affect hormone levels differently.