11 citations
,
October 2023 in “mSphere” This study reported that the PrrH sRNA in *Pseudomonas aeruginosa* may directly regulate genes involved in pyochelin siderophore biosynthesis, highlighting its role in adapting to heme availability, with light conditions influencing this gene expression.
1 citations
,
April 2015 in “InTech eBooks” RAGE is a potential target for melanoma treatment, but its effectiveness is uncertain due to variable expression levels.
April 2010 in “The Journal of Urology” This study found that ureteroileal anastomosis with direct intraluminal visualization had a 4.2% stricture rate, which compares favorably to other techniques with rates between 3.5% and 11.1%.
December 2005 in “Dermatologic surgery” This study found that while Er:YAG laser therapy can initially improve the appearance of eruptive vellus hair cysts, it was ineffective in preventing early recurrences due to limitations in ablation depth.
56 citations
,
July 2014 in “PloS one” This study found that selective androgen receptor modulators (SARMs) significantly inhibited tumor growth and metastasis-promoting factors in AR-positive triple-negative breast cancer models.
November 2025 in “Journal of Investigative Dermatology” Estetrol may help prevent hair loss and support hair growth in women.
5 citations
,
September 2015 in “BMC Medical Genetics” In this study, individuals with a c.1072C > T mutation in the EDAR gene showed more hair shaft deformations compared to non-mutation carriers, highlighting EDAR's role in hair follicle development.
3 citations
,
April 2010 in “The FASEB Journal” This study found that estrogen, through estrogen receptors, can regulate the expression of the HOXC13 gene involved in hair follicle development, with MLL3 histone methylase playing a collaborative role.
22 citations
,
December 2016 in “PloS one” In this study, researchers found that the EDMTFH protein is present in specific layers of the chicken embryo skin and feathers, suggesting its role in feather mechanics and development.
3 citations
,
January 2011 in “Annals of Dermatology” This study found that EGFR inhibitors and ligands did not significantly affect the expression of inflammatory biomarkers in cultured sebocytes, except for a notable increase in IL-1 expression with EGF treatment.
44 citations
,
January 2023 in “New Phytologist” This study found that low temperature triggers root hair elongation in Arabidopsis thaliana through a FERONIA-ROP2-TORC signaling pathway, also activated by nitrogen deficiency.
March 2026 in “Institutional Repositories DataBase (IRDB)” This study observed an association between intense itching in anterior chest keloids and an increased density of nerve fibers in the epidermis, alongside elevated expression of the pruritus mediator substance P, though no difference was found in Langerhans cells related to pruritus, location, or region.
November 2022 in “Journal of Investigative Dermatology” This study identified 15 Iranian patients with PLEC variants linked to various plectinopathies and highlighted a novel association between a homozygous nonsense variant in PLEC and a rare combination of disorders including EB pruriginosa, muscular dystrophy, and congenital myasthenic syndrome.
35 citations
,
May 2015 in “Thrombosis Research” This review synthesizes knowledge on Prostaglandin E2's role in platelet biology and suggests that targeting PGE2 pathways could lead to personalized antiplatelet therapy without affecting hemostasis, but it presents no new results.
193 citations
,
June 1990 in “Journal of Investigative Dermatology” 346 citations
,
April 2020 in “Frontiers in Oncology” This review discusses the roles of key epithelial-mesenchymal transition factors and potential therapeutic opportunities involving cancer metabolic pathways, reporting no new clinical results.
67 citations
,
October 2005 in “Annals of Oncology” This review found that fulvestrant is well tolerated in postmenopausal women with hormone receptor-positive advanced breast cancer, showing lower incidence of joint disorders than non-steroidal aromatase inhibitors.
5 citations
,
January 2018 in “Indian Journal of Dermatology/Indian journal of dermatology” This case report describes a 40-year-old woman who developed erythema annulare centrifugum, a type of skin rash, likely triggered by taking the drug aceclofenac.
2 citations
,
January 1975 in “Archives of Dermatological Research” Certain enzymes react strongly with some hormones in rat skin during hair growth, mainly in sebaceous glands and hair sheaths.
30 citations
,
June 2014 in “Seminars in Immunology” This review discusses recent advances in understanding the Eda pathway's role in developmental biology, and highlights ongoing trials and areas for further research, including Eda's potential involvement in cell processes and disease.
18 citations
,
April 2001 in “Bioorganic & Medicinal Chemistry Letters” This study identified the N-(iodopropenyl) derivative 13 as a promising candidate for development as a radioiodinated androgen receptor ligand due to its binding affinity.
March 2025 in “Laboratory Investigation” This systematic review found that mixed epithelial and stromal tumor of the seminal vesicle (MESTSV) is characterized by abundant stromal proliferation, architectural heterogeneity, and strong immunoreactivity for ER/PR, with most being benign but warranting surveillance for possible recurrence or metastasis.
15 citations
,
February 2017 in “Nursing Clinics of North America” This article reviews common skin reactions associated with epidermal growth factor receptor inhibitors and reports no new clinical findings, emphasizing the need for understanding nursing care and oncodermatology.
20 citations
,
February 2019 in “Genes” This study identifies a likely pathogenic homozygous missense variant in the AEBP1 gene in a patient with symptoms of classical Ehlers-Danlos syndrome, suggesting new perspectives for EDS classification and research.
14 citations
,
July 2016 in “Journal of Endocrinology” This study observed that equine epididymis mainly expresses the type 1 isoform of 5α-reductase and effectively converts progesterone and testosterone to DHP and DHT, while finasteride and dutasteride inhibited this activity.
1 citations
,
January 2025 in “Frontiers in Oncology” This review highlights REV7's crucial roles in maintaining genome stability, its implication in several cancers, and its association with poor prognoses and treatment resistance, while also noting that REV7 suppression may improve chemotherapy sensitivity.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that deleting Ube2n in adult mouse skin leads to inflammation and other skin changes, and identifies IRAK1/4 as potential treatment targets for inflammatory skin disorders.
34 citations
,
July 2011 in “International journal of pharmaceutics” This study found that ion-paired solutions significantly improved the skin penetration of risedronate in hairless mice compared to risedronate alone.
January 2012 in “Zhongguo shouyi xuebao” In this study, significant differences in the expression of type I IRS keratin genes were observed in the groins of three sheep breeds during wool growth, related to hair follicle density.
291 citations
,
April 2010 in “Gastroenterology” This study identified Lgr5 and Lgr6 as receptors expressed by small populations of stem cells in various adult organs, with Lgr5+ve cells forming long-lived organoids in certain mouse models.