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The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.

Dermatoscopy is useful for identifying different hair and scalp conditions and can reduce the need for biopsies.

Hair loss and aging are caused by the breakdown of a key protein in hair stem cells.

Fat cells help recruit healing cells and build skin structure during wound healing.

The report recommends personalized treatment for women's sexual dysfunctions and more research on effective therapies.

Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Understanding where cancer cells come from helps create better prevention and treatment methods.

Hair loss in women is genetic, diagnosed by examination and biopsy, and treated with minoxidil, finasteride, or transplantation.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Eph receptors and ephrins may be promising targets for treating diseases, but more understanding is needed for effective and safe therapies.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

Adding anti-Müllerian hormone to PCOS criteria lowers the number of women diagnosed.

The Rotterdam Study aims to understand various diseases in older adults.

Chemotherapy causes hair loss by damaging hair follicles and stem cells, with more research needed for prevention and treatment.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Using the eye pressure medication latanoprost can cause excessive hair growth and darker eyelashes on the treated eye.

Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.

Sorafenib is effective in treating Desmoid Tumor/Deep Fibromatosis.

The document provides a method to classify human hair growth stages using a model with human scalp on mice, aiming to standardize hair research.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Keratins are crucial for cell structure, growth, and disease risk.

Hair follicles help absorb and store topical compounds, aiding targeted drug delivery.

Androgens can both increase and decrease hair growth in different parts of the body.

Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.

Pregnancy can cause various skin changes and diseases, with PUPPP being the most common skin condition specific to pregnancy.

Lactate production is important for activating hair growth stem cells.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Calcium affects where root hairs grow, but other unknown factors determine their growth direction.