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Future hair loss treatments should aim to extend hair growth, reactivate resting follicles, reverse shrinkage, and possibly create new follicles, with gene therapy showing promise.

Androgens can both promote and prevent hair growth due to differences in gene expression in hair follicles.

A position effect on the TRPS1 gene causes excessive hair growth in humans and mice.

The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.

Hairless protein can both repress and activate vitamin D receptor functions, affecting gene regulation.

lncRNA XLOC_008679 and gene KRT35 affect cashmere fineness in goats.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

Menopause causes significant changes in the vaginal introitus, but less so in the labia majora, which may lead to symptoms of vaginal atrophy.

ELL is crucial for gene transcription related to skin cell growth.

KDML105 bran extract may help with hair growth and prevent hair loss.

A new MBTPS2 gene variant disrupts fat metabolism and collagen production, causing Osteogenesis imperfecta.

The conclusion is that the nuclear lamina and LINC complex in skin cells respond to mechanical signals, affecting gene expression and cell differentiation, which is important for skin health and can impact skin diseases.

A rare ITGB6 gene variant causes intellectual disability, hair loss, and dental issues.

Cyanidin 3-O-arabinoside may help treat a common form of hair loss by protecting cells against aging and improving cell function.

Deleting the PTEN gene in mice causes nerve cells to grow larger and heal better after injury, but may cause overgrowth and hair loss in older mice.

Removing a specific gene in certain skin cells causes hair loss on the body by disrupting normal hair development.

Enhancers and super-enhancers are key in controlling specific gene activity and can play a role in cancer development.

Researchers used CRISPR/Cas9 to create a goat with a gene that increased cashmere production by 74.5% without affecting quality.

A Japanese patient with IFAP syndrome had a severe MBTPS2 gene mutation but showed milder symptoms than previously observed cases.

Efficient delivery systems are needed for the clinical use of CRISPR-Cas9 gene editing.

Short photoperiods improve cashmere growth and quality in goats by changing hormone levels and gene expression.

UV radiation may cause DNA changes in skin, certain UVB therapy helps psoriasis, a new gene mutation is linked to mild piebaldism, different immune cells affect psoriasis, a drug promotes hair growth, and some cancer drugs could treat skin barrier issues.

A defective protein in progeria causes cell death and atherosclerosis, but a treatment targeting cell stress may reduce these effects.

CK 5/6 expression in breast cancer is linked to negative hormone receptor status and higher tumor grade.

The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.

Chinese black tea extract helped mice grow hair, especially when combined with capsaicin.

848 genes related to fat and metabolism are less active in people with Central Centrifugal Cicatricial Alopecia.

The document concludes that understanding hair follicle biology can lead to better hair loss treatments.

Lactate production is important for activating hair growth stem cells.

Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.