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Lack of cystatin M/E causes thin hair and dry skin.

A five-month-old boy with Omenn syndrome successfully recovered after a stem cell transplant with reduced intensity conditioning.

Herpes gestationis is linked to certain antigens, atopic eczema affects T cell populations and may be eased by breastfeeding, higher doses of anti-androgen treatment can improve androgenic alopecia, topical minoxidil increases hair thickness, long-term methotrexate therapy can cause liver fibrosis in psoriasis patients, and Lichen Sclerosus et Atrophicus patients aren't at higher risk for autoimmune disorders.

Mice lacking the PPARγ gene in their fat cells had almost no fat tissue, severe metabolic problems, and abnormal development of other fat-related tissues.

Targeted cancer therapies often cause serious skin problems that need careful management.

The PDGF/PDGFR pathway is a potential drug target with mixed success in treating various diseases, including some cancers and fibrosis.

Understanding how cells die in the skin is important for treating skin diseases and preventing hair loss.

FOXN1 gene variants cause low T cells and immune issues from birth.

Men are more likely to get infectious skin diseases, while women are more prone to autoimmune and pigment-related skin conditions, influenced by biological and environmental factors.

Pigmented casts are common in several hair loss conditions and can help diagnose specific types of alopecia.

A man had an allergic reaction to minoxidil, which stopped after he discontinued use and started corticosteroids.

Levodopa for Parkinson's disease might be linked to skin issues like melanoma, but it's unclear if the drug or the disease causes them.

Combining skin tissue pathology with genetics has greatly improved the diagnosis and understanding of certain skin diseases.

Burn scars heal abnormally and more research is needed to find better treatments.

Some acne medications have side effects; doctors should educate patients and may not need to do frequent lab tests for all.

Human sebaceous glands can grow back in skin grafts on mice and work like normal human glands.

Burn scars form abnormally due to changes in wound healing, and more research is needed to improve treatments.

Dermoscopy helps doctors recognize a type of benign skin tumor called pilomatricoma.

Removing a testicular tumor in a dog reduced its aggressive behavior and skin problems.

Cancer treatments targeting specific cells often cause skin, hair, and nail problems, affecting patients' lives and requiring careful management.

Acne vulgaris is a common skin condition that can cause low self-esteem and depression, and early treatment is important to prevent scarring.

Obesity affects skin health, causing conditions like acanthosis nigricans and may require different treatment approaches.

JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.

The document concludes that accurate diagnosis of ichthyosis is crucial for treatment and genetic advice, and ongoing research is needed for better therapies.

Transplant success has improved with better immunosuppressive drugs and donor matching.

Understanding hair follicle anatomy helps diagnose hair disorders.

Foxp3 is crucial for regulatory T cell function, and targeting these cells may help treat immune disorders.

Vitamin D has potential benefits for cancer prevention, heart health, diabetes, obesity, muscle function, skin health, and immune function, but clinical results are mixed and more research is needed.

Adult female acne treatment should be personalized, considering individual preferences and pregnancy, using various topical and oral medications while managing side effects and resistance.

Smoking harms the skin, causing early aging and increasing cancer risk, but stopping smoking can improve skin health.