September 2018 in “Value in Health” In this study, researchers found that in Germany, orphan drugs with a phase III study and no comparable treatments available tend to receive higher HTA scores. There was no significant correlation between HTA scores and orphan drug prices or discount rates.
92 citations
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May 2004 in “Journal of Investigative Dermatology”
February 2016 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” This study reports a novel mutation in the TP63 gene associated with T and B cell lymphopenia in an EEC patient, suggesting that EEC diagnosis should include TREC assay and evaluation for immunodeficiency.
4 citations
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February 2019 in “BioMed Research International” In this study, ebastine significantly increased the proliferation of human follicle dermal papilla cells and may contribute to hair regrowth by activating the ERK signaling pathway.
This study found that overexpression of erythropoietin disrupted hair growth in mice by affecting dermal fat lipogenesis and lipolysis, leading to poor hair follicle development and truncal alopecia.
15 citations
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January 1995 in “Archives of dermatological research” In this study, OCT showed strong nuclear binding in certain skin cells, suggesting similar genomic effects to vitamin D with potential therapeutic benefits due to its lower calcaemic effect.
2 citations
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May 2012 in “Annals of Oncology” This study found that patients with ovarian metastases from breast cancer had a better prognosis after tumor debulking if they exhibited high estrogen and progesterone receptor expression in both the primary tumor and metastases.
2 citations
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July 2022 in “Cureus” This report presents the first known case of ulerythema ophryogenes in a 28-year-old male in Saudi Arabia.
October 2019 in “Obsgyne Review Journal of Obstetric and Gynecology of Siddharth Health Research and Social Welfare Society” This study observed that PCOS presents frequently with cutaneous symptoms and affects both obese and non-obese women, highlighting the importance of interdisciplinary care for effective management.
September 2024 in “Journal of Cosmetic Dermatology” In this study, researchers found that Ectoin, derived from halophilic bacteria, can mitigate stress-related skin damage by reducing cortisone's inhibitory effects on essential skin proteins and decreasing UVB-induced glucocorticoid activity, highlighting its potential as a preventative agent for stress-induced skin issues.
11 citations
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January 2016 in “Evidence-based Complementary and Alternative Medicine” This study found that rice bran ash extract and orthosilicic acid both increased melanin synthesis and related protein expression in melanocytes, suggesting potential therapeutic use for melanin deficiency.
June 1996 in “Journal of Dermatological Science”
4 citations
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May 2024 in “The Lancet” This study aims to compare the safety and effectiveness of bariatric surgery versus medical care on ovulation rates in women with PCOS and obesity, as current observational data suggests surgery may improve fertility prospects, but no randomized trial has yet confirmed this effect.
January 2015 in “Durham e-Theses (Durham University)” This study found that glucose starvation and hypoxia are physiological triggers of ER stress in in vitro differentiated adipocytes, rather than high concentrations of saturated fatty acids, cholesterol, or proinflammatory cytokines.
67 citations
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October 1997 in “Dermatologic Surgery” This study found that the EpiLight Hair Removal System achieved approximately 60% hair removal after 12 weeks following a single treatment, indicating effectiveness and safety for long-term hair reduction.
15 citations
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June 2021 in “Medicina” This study found that combined intense pulsed light and low-level light therapy significantly improved ocular surface outcomes and quality of life for patients with meibomian gland dysfunction and dry eye disease.
April 2020 in “Journal of the Endocrine Society” This case report describes the first known instance of a testosterone-secreting steroid cell ovarian tumor causing pulmonary embolism and erythrocytosis in a postmenopausal woman, highlighting its potential role as a rare cause of hypercoagulable state.
June 2026 in “Ophthalmology and Therapy” This review concluded that near-infrared and red light photobiomodulation shows potential for certain ocular conditions like age-related macular degeneration and dry eye disease, but clinical evidence is still mixed and insufficient to establish it as a standard therapy.
78 citations
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January 2013 in “Brachytherapy” This study found that high-dose-rate electronic brachytherapy was effective for treating nonmelanoma skin cancer, with no recurrences and good to excellent cosmetic results at 1 year or more.
April 2023 in “Journal of Investigative Dermatology” In this study, bariatric surgery in patients with morbid obesity improved various skin conditions, although acute telogen effluvium was common, with notable reductions in facial sebum and skin elasticity changes.
January 2024 in “Brazilian Journal of Veterinary Pathology” In this case report, veterinarians observed a 16-year-old mare with symptoms including chronic weight loss, pruritus, muscle atrophy, and lameness, which gradually progressed to neurological issues despite initial treatment.
January 2022 in “Chemistry: A European Journal” This study found that synchrotron radiation ECD imaging provides new insights into solid-state Finasteride by highlighting the significant role of anisotropy in local domains for chiroptical measurements.
July 2023 in “Clinical Cosmetic and Investigational Dermatology” In this case report, a 64-year-old Thai woman with a history of misdiagnosed eczema or folliculitis was ultimately found to have granular parakeratosis of the eccrine ostium, leading to significant symptom improvement once accurately diagnosed and advised to avoid excessive heat and moisture.
December 2018 in “Journal of Nursing UFPE on line” This entry describes the 13th edition of the book "Obstetrícia" by Jorge de Rezende Filho and Carlos Antônio Montenegro, published in 2014, but reports no new research findings.
July 2025 in “Journal of Investigative Dermatology” Tissue-engineered skin substitutes can model junctional epidermolysis bullosa and may help develop gene therapy.
42 citations
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May 2009 in “Contraception” This study found that the combined oral contraceptive containing ethinyl estradiol and chlormadinone acetate was effective in reducing moderate papulopustular acne and other androgen-related skin disorders compared to placebo.
4 citations
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September 2011 in “American Journal of Clinical Dermatology” This case series suggests that EE/CMA 0.03mg/2mg may help manage dermatological disorders related to androgen excess, as evidenced by symptomatic improvements in the four patients treated.
This editorial comments on a European registry evaluating the symptomatic effectiveness of pharmacological treatments for benign prostatic enlargement and presents no new research findings.
1 citations
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May 2024 in “International journal of medicine and psychology.” In this study, researchers found that using electromagnetic radiation in the EHF range enhanced the engraftment of skin flaps in rats by improving microcirculation and reducing necrosis, with greater effects observed when paired with systemic ozone therapy.