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The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

Oxidative stress is a key factor in the development of Polycystic Ovary Syndrome, and weight management can improve symptoms.

A position effect on the TRPS1 gene causes excessive hair growth in humans and mice.

ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.

Male pattern hair loss caused by follicular miniaturization; early diagnosis and treatment can reduce psychological burden.

17β-estradiol can reduce inflammation in the skin.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Athletes use steroids to enhance performance despite health risks and legal issues, and education on their dangers is needed.

Tofacitinib is somewhat effective for alopecia areata, but more research is needed on its safety and long-term effects.

New treatments for Hepatitis C show promise but need more research to confirm their safety and effectiveness for clinical use.

Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Finasteride for hair loss may cause long-lasting side effects like impotence and low libido, but trials lack proper safety reporting.

5-α-reductase inhibitors reduce prostate cancer risk but may cause sexual dysfunction and don't affect high-grade tumor or death rates.

Dutasteride treatment in men with mild to moderate COVID-19 reduced viral shedding, inflammation, and recovery time without serious side effects.

5-alpha reductase inhibitors slightly increase the risk of sexual and mood side effects, and breast growth in men.

Microencapsulation helps protect and track therapeutic cells, showing promise for treating various diseases, but more work is needed to improve the technology.

Rice bran extract can potentially treat hair loss by promoting hair growth and increasing the number of hair follicles.

MicroRNAs are important for skin health and could be targets for new skin disorder treatments.

The document concludes that new treatments are needed to better manage acne and reduce side effects related to current therapies.

Women with PCOS have higher levels of certain blood clotting factors, suggesting a greater risk of cardiovascular issues.

Early hair loss may indicate prostate issues.

The conclusion is that androgenetic alopecia and senescent alopecia have unique gene changes, suggesting different causes and potential treatments for these hair loss types.

Researchers found new genes involved in hair growth, which could help develop new hair treatments.

Finasteride and dutasteride reduce unwanted movements from Parkinson's disease treatment by normalizing certain brain signals.

The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.

Androgenic steroids can slow down or stop the growth of certain skin fungi.

Genetic discoveries are key for understanding, diagnosing, and treating inherited hair and nail disorders.

Birth control pills help treat skin and hair growth problems linked to high male hormone levels.