Search

everythinglearnresearchcommunity

for

Search:↓

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

Cyclodextrins improve how steroid drugs work and are used in marketed medications and environmental applications.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Overweight women with PCOS have higher levels of certain hormones that could indicate a higher risk of heart and metabolic problems.

The enzyme 5α-reductase type 1 is important for blood vessel development and fertility in the uterus.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

The structure of SRD5A reveals how it reduces steroids, aiding drug design for related health conditions.

Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Genetic and environmental factors, like smoking and exercise, affect male hair loss.

Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.

Hibiscus plant extracts may have health benefits like lowering blood pressure and protecting the heart.

Fermentation of Finasteride with Ocimum sanctum L. creates new metabolite that inhibits tyrosinase.

Certain metabolites are lower in women with PCOS and could be potential markers for the condition.

PSA levels could help detect illegal steroid use in female athletes but face challenges like cost and PCOS prevalence.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.

The document concludes that better biomarkers are needed to detect long-term oral testosterone use in athletes.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.

Finasteride treatment in male rats causes long-lasting effects on depression-like behavior, brain cell growth, inflammation, and gut bacteria composition.

Nandrolone might increase muscle mass with fewer side effects than testosterone but could cause erectile dysfunction and needs more research.

New tests detect finasteride and dutasteride in urine quickly and easily.

Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.

Testosterone reduces key molecules needed for early pregnancy in rats.

C60 fullerenes can alter protein function and may help develop new disease inhibitors.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Finasteride affects brain processes related to neurotransmission and metabolism, potentially helping with neuropsychiatric conditions.

Finasteride and analogues separated using LC-MS-MS technique.

Abusing steroids can damage your heart, muscles, reproductive system, liver, skin, and brain, and may increase the risk of Alzheimer's disease.

Angiopteris evecta extracts significantly promote hair growth in rabbits.