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Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Acne is caused by multiple factors including oil production, bacteria, inflammation, and possibly diet and environment.

Flutamide and a new synthetic steroid affected brain and prostate chemicals and showed potential for treating androgen-related conditions and epilepsy.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

The combination of cyproterone acetate and testosterone enanthate is highly effective in preventing sperm production and could be a good reversible male contraceptive.

Mutations in the SRD5A3 gene cause a new type of glycosylation disorder by blocking the production of a molecule necessary for protein glycosylation.

Certain miRNAs may play a role in sheep hair follicle development, which could help improve wool production.

Skin lesions in Carney complex are likely caused by a specific group of skin cells that promote pigment production due to a genetic mutation.

Scientists restored fertility in male mice lacking a key fertility gene by using a modified gene.

Testosterone replacement can help menopausal women with various symptoms, but should be used carefully and is not yet officially licensed in the UK for women.

Certain pesticides and fungicides can interfere with male hormone functions, potentially causing reproductive issues in male rats.

Testosterone may slow down wound healing and increase inflammation.

TRPV3 could be a target for treating pain, skin disorders, and hair problems, but more research is needed to create effective drugs.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

New treatments for male hypogonadism are effective and should be personalized.

Finasteride, a hair loss drug, may cause long-term sexual side effects due to changes in hormone receptor levels.

Runx1 controls fat-related genes important for normal and cancer cell growth, affecting skin and hair cell behavior.

Both treatments reduced androgen levels and hair growth in women with hirsutism.

Overweight women with PCOS have higher levels of certain hormones that could indicate a higher risk of heart and metabolic problems.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

The dermal papilla is crucial for hair growth and health, and understanding it could lead to new hair loss treatments.

Adults with polycystic ovary syndrome are much more likely to have obstructive sleep apnea.

Nonclassic adrenal hyperplasia is a genetic condition that can cause early puberty and fertility problems, treated with specific steroids.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.

Sex hormone treatments can increase muscle mass in older adults but have inconsistent effects on muscle function and may carry cardiovascular risks.

Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.