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Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Women with PCOS have overall higher body fat, not abnormal fat placement, and more insulin resistance.

Treating sleep apnea in young obese women with PCOS can improve heart health and insulin sensitivity.

Women with PCOS who have low SHBG are more likely to have low good cholesterol and metabolic syndrome.

Hirsutism is a strong sign of high male hormones and metabolic problems in women with PCOS, but acne and hair loss are not.

Fulvestrant is a well-tolerated new treatment for advanced breast cancer that may delay chemotherapy.

Myo-inositol helps improve skin conditions and metabolic profiles in young women with PCOS.

Women with PCOS often experience anxiety, depression, and a lower quality of life.

The current methods for diagnosing polycystic ovary syndrome are too vague and may lead to misdiagnosis and problems in research.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

Women with PCOS tend to have higher anxiety and depression levels compared to healthy women.

Women with PCOS are more likely to have fatty liver disease and worse metabolic health.

Aromatase inhibitor therapy for breast cancer increases the risk of hair loss and thinning.

The study suggests that being overweight or obese, not PCOS itself, is strongly linked to insulin resistance.

Young women with PCOS have a higher risk of high blood pressure and metabolic syndrome, but these risks may decrease after age 40.

The PCOSQ-50 is a valid and reliable questionnaire for measuring quality of life in Iranian women with PCOS.

People with hair loss may have different levels of certain hormones due to changes in hormone processing.

Hair loss is often linked to thyroid problems, especially in women and older people, and screening for thyroid issues is advised for those with hair loss.

Women with PCOS, especially those overweight, have higher levels of IL-18 in their endometrium, which may affect fertility.

The research suggests that the ZP4 gene is linked to egg development in women with PCOS but requires more study to understand its role in infertility.

Selenium might help with insulin resistance and cholesterol in PCOS, but more research is needed to confirm its benefits.

Vitamin D deficiency is common in women with PCOS and linked to some metabolic problems, but not the main cause of their metabolic issues.

PCOS lowers quality of life, causing issues like obesity, infertility, and menstrual problems.

Australian doctors experienced in adult transgender healthcare mostly prescribe intramuscular testosterone and oral estradiol, recommend mental health assessments before hormone therapy, and support improved training and guidelines.

Irregular menstrual cycles in teenagers are linked to a higher risk of polycystic ovary syndrome and metabolic syndrome.

AMH is a good marker for diagnosing PCOS, but global standards are needed.

Patients with PCOS tend to score their hirsutism higher than clinicians, making self-scoring less useful for diagnosis.

Birth control pills containing cyproterone acetate improve the quality of life more for women with polycystic ovary syndrome after 6 months of use.

Insulin resistance is not more common in idiopathic hirsutism patients than in healthy individuals.

Managing emotional distress, obesity, insulin resistance, and high male hormones is crucial for improving well-being in women with PCOS.