1 citations
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April 2025 in “Clinical Cosmetic and Investigational Dermatology” This report describes a rare case of porokeratotic eccrine ostial and dermal duct nevus in a 64-year-old woman, successfully treated with CO₂ laser, highlighting its potential occurrence in older adults.
May 2025 in “The Journal of Rheumatology” In this case report, a 64-year-old woman diagnosed with both NMOSD and SLE showed mild improvement in vision and recovered from thrombocytopenia after treatment with glucocorticoids and Rituximab, highlighting the importance of accurate diagnosis and tailored treatment for overlapping autoimmune disorders.
24 citations
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May 2019 in “PLOS genetics” This study reports that compound heterozygous loss-of-function mutations in the HEPHL1 gene in a child were associated with abnormal hair and cognitive issues, linking altered ferroxidase activity to hair disorders.
April 2016 in “Journal of The American Academy of Dermatology” Ixekizumab is effective and safe for patients who did not improve with etanercept treatment for psoriasis.
14 citations
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November 1987 in “Journal of The American Academy of Dermatology” A woman developed a severe skin reaction called toxic epidermal necrolysis after taking the antibiotic cephalexin.
3 citations
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August 2017 in “Clinical case reports” A rare skin condition causes red and dark patches on the face and limbs.
60 citations
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January 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that inhibiting PKC-β activity with bisindolylmaleimide reduces pigmentation in the skin and hair of guinea pigs and mice by preventing tyrosinase activation.
29 citations
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December 2017 in “Molecular therapy” This study found that enzyme replacement therapy in mice with a severe form of classical homocystinuria improved metabolic patterns and alleviated many clinical symptoms.
April 2005 in “Journal of Investigative Dermatology” This compilation reviews multiple dermatologic studies, reporting findings such as the lack of a psoriasis-susceptibility allele in cluster 17, and highlighting a mouse model for studying hair follicle formation, among others.
May 2026 in “AAPS PharmSciTech” This study found that PEGylated LUT-Aspasomes significantly improved neuroprotective effects in stressed rats, enhancing spatial memory, reducing depressive-like behavior, and preserving hippocampal architecture better than free luteolin. Additionally, it increased brain delivery and stability, suggesting potential for treating stress-related neurobehavioral disorders.
This case report details the occurrence of paroxysmal nocturnal haemoglobinuria in a 19-year-old woman with systemic lupus erythematosus to raise clinician awareness of this rare association.
21 citations
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October 2017 in “Cell death and disease” This study found that the absence of the stress-responsive protein Sesn2 increased hair cell susceptibility to gentamicin in the inner ear, indicating Sesn2's potential protective role against aminoglycoside-induced damage.
March 2026 in “Dyes and Pigments” This study found that genipin-based pigments, accelerated by riboflavin and blue-light photocatalysis, achieved commercial-level hair dye results with enhanced gloss and excellent color retention while reducing cuticle disruption, offering a potentially safer and faster alternative to traditional hair coloration methods.
January 2016 in “Zurich Open Repository and Archive (University of Zurich)” This study concludes that dietary L-serine supplementation shows promise as a long-term therapy for hereditary sensory and autonomic neuropathy type 1, reducing neurotoxic 1-deoxysphingolipid levels and improving symptoms in severe cases.
This study found that in early retinal neurogenesis in mice, the transcription factor Lhx2 regulates Sonic Hedgehog signaling by controlling expression of pathway genes like the co-receptors Gas1 and Cdon.
November 2024 in “PubMed” This case report describes an 18-month-old boy who developed a rare phototoxic skin reaction to terbinafine, likely triggered by sunlight exposure, which resolved after treatment with corticosteroid cream and sun avoidance.
6 citations
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September 2022 in “Frontiers in pharmacology” In this study, Epimedii Folium extract was found to enhance melanin production and promote pigmentation through mechanisms involving the MAPK/ERK1/2 pathway in both in vitro and in vivo models.
September 2019 in “Journal of Investigative Dermatology” This study found that mosaic mutations in the CARD14 gene are linked to inflammatory linear verrucous epidermal naevus in two patients, who experienced significant improvement with the IL12/IL23 inhibitor Ustekinumab.
1 citations
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February 1991 in “Journal of Biological Chemistry”
March 2026 in “Science China Materials” SeV-Tp speeds up healing of drug-resistant infections by targeting wounds and killing bacteria with light activation.
January 2015 in “OpenBU/Boston University Institutional Repository (Boston University)” This study reported that NRP2 expression in melanocytes and melanocyte stem cells is linked to migration inhibition and potentially melanoma progression, suggesting its role as a target for understanding melanoma and hair follicle biology.
17 citations
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October 2006 in “Molecular and Cellular Endocrinology” This study found that the L457(3.43)R mutation in the human luteinizing hormone receptor increases phosphodiesterase activity, reducing hormonal response despite elevated basal cAMP levels.
5 citations
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January 2015 in “Case reports in medicine” In this case report, a novel missense mutation c.1360G>C (p.Ala454Pro) in the MBTPS2 gene was identified in a boy with typical IFAP syndrome and severe atopic features, although no phenotype/genotype correlation was established.
17 citations
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April 2004 in “Acta Clinica Belgica” This study found that ultraviolet light-enhanced visualization can detect subtle skin changes linked to carotene and vitamin A deficiency, which improved with dietary correction in deficient individuals.
10 citations
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November 2009 in “Pigment cell & melanoma research” This study by Pérez-Oliva et al. explored how Mahogunin Ring Finger-1 (MGRN1) affects melanocortin-1 receptor (MC1R) signaling, suggesting that MGRN1 competitively inhibits Gαs binding to MC1R, influencing pigment production.
November 2022 in “Journal of Investigative Dermatology” This study developed a chalcone-based molecule that significantly increased tyrosinase inhibition and solubility, showing potential as a safe and effective skin depigmenting and antiaging agent, with supportive epigenetic and antioxidant properties observed in vitro.
August 2000 in “Microscopy and Microanalysis” This study used novel methods to detect and map iodine concentrations in pig skin, finding iodine present in the coating, stratum corneum, and tissue around hair follicles.
1 citations
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December 2022 in “Pediatric dermatology” This case report highlighted an instance of lichen spinulosus emerging as a new cutaneous sequela in a boy following toxic epidermal necrolysis, responding to treatment with ammonium lactate.
January 2025 in “Journal of College of Physicians And Surgeons Pakistan” In this case report, a 36-year-old woman with GAPO syndrome underwent successful XEN gelatin micro-stent implantation in both eyes to control primary open-angle glaucoma that was unresponsive to medical treatment, marking the first documented use of this minimally invasive glaucoma surgery in such a patient.
32 citations
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April 2001 in “Experimental Eye Research” Zinc is essential for healthy optic nerves, and its deficiency can damage them.