8 citations
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December 2015 in “JAMA ophthalmology” This abstract contains no research results; it's a website navigation menu and institutional policy information from JAMA Ophthalmology.
8 citations
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June 2024 in “Pharmaceutics” This study found that using elastic nano-liposomes to deliver palmitoylethanolamide improved its transdermal delivery and enhanced its skincare effects, with minimal cytotoxicity and no allergic reactions observed.
5 citations
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February 1977 in “Archives of Dermatology” This study reports that 14 of 19 patients with erythema nodosum leprosum had C3 deposits in vessel walls when examined using direct immunofluorescence.
January 2009 in “IRIS UNIMORE (University of Modena and Reggio Emilia)” This study suggests that neurosteroids may influence epileptogenesis in a pilocarpine model of temporal lobe epilepsy, as indicated by the modulation of seizure activity following P450 scc upregulation and finasteride treatment in rats.
12 citations
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January 1987 in “Ophthalmic Paediatrics and Genetics” This report describes a patient with biotinidase deficiency presenting bilateral optic atrophy, and confirms autosomal recessive inheritance through enzyme dosage analysis in the patient and family members.
June 1998 in “Pathophysiology” This summary offers an overview of selenium's forms, its biological roles, and dietary sources, but reports no specific research findings.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that low-dose blue light (453nm) may positively affect hair growth by interacting with the receptors CRY1 and OPN3 in hair follicle cells.
32 citations
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September 1966 in “Journal of Investigative Dermatology”
3 citations
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June 2015 in “Serbian Journal of Dermatology and Venereology” In this study, secondary syphilis presented diverse clinical manifestations, with syphilitic alopecia occurring only in HIV-positive patients, underscoring the importance of considering syphilis in differential diagnoses for vulnerable populations.
2 citations
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September 2022 In this study, researchers found that a PER3 gene SNP may be pathogenic for a new subtype of dyschromatosis universalis hereditaria, especially when combined with a SASH1 mutation.
23 citations
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February 2004 in “Clinical and Experimental Ophthalmology” This case report describes a 68-year-old woman with metastatic breast cancer who experienced significant improvement in visual acuity after stopping tamoxifen, which was associated with bilateral optic neuropathies.
19 citations
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December 1990 in “Journal of Histochemistry & Cytochemistry” This study found that cultured human foreskin cells and a human keratinocyte cell line continue to express specific cytochrome P450 isoenzymes, unlike keratinocytes derived from hair follicles.
July 2023 in “Current Issues in Molecular Biology” This study found that escin acts as a natural agonist of the Wnt/β-catenin signaling pathway in cultured human dermal papilla cells by promoting the degradation of GSK-3β, highlighting its potential therapeutic use for conditions like androgenetic alopecia and vitiligo.
2 citations
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June 2004 in “Journal of Molecular Histology” January 2024 in “SAGE Open Medical Case Reports” In this study, exome sequencing revealed that two brothers with ichthyosis, born to consanguineous parents, had NIPAL4 autosomal recessive congenital ichthyosis, while the older brother's blindness resulted from separate mutations in the peroxidasin gene, which were also found in an unaffected sister.
10 citations
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September 2022 in “Journal of Biophotonics” This study analyzed clinical and histological reports and concluded that blue light therapy is safe for human skin, with potential photoprotective effects against UV irradiation due to its impact on skin pigmentation mediated by Opsin-3.
1 citations
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May 2025 in “Natural Products and Bioprospecting” In this study, PEVIII, a nanocomposite chitosan-coated vesicle containing both α-hederin and hederacoside C, demonstrated notable antibacterial activity against Pseudomonas aeruginosa in a keratitis model, showing significant lesion reduction, tissue improvement, and decreased bacterial load and inflammatory markers compared to other treatments.
August 2026 in “Frontiers in Pharmacology” In this case report, a 27-year-old woman experienced severe multisystem toxicity, including toxic encephalopathy, vision, and hearing loss, after ingesting selenium at occupationally high doses, suggesting such exposure can lead to previously unreported effects of vision and hearing impairment.
2 citations
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May 2020 in “Journal of visualized experiments” This study describes a protocol for inducing endogenous reactive oxygen species in mouse skin, which stimulates tissue regeneration and promotes burn healing and hair follicle growth.
1 citations
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January 2022 in “Annals of Dermatology” In this case report, researchers identified a novel homozygous missense mutation in the MBTPS2 gene associated with the mild form of IFAP syndrome in a 7-year-old boy.
This study utilized a pigmented human epidermal equivalent model to incorporate melanocytes into the epidermis and found enhanced differentiation potential compared to conventional in vitro systems, reflecting in vivo cellular trajectories and highlighting melanocyte-to-keratinocyte communication pathways.
November 2022 in “Journal of Investigative Dermatology” This study identified 15 Iranian patients with PLEC variants linked to various plectinopathies and highlighted a novel association between a homozygous nonsense variant in PLEC and a rare combination of disorders including EB pruriginosa, muscular dystrophy, and congenital myasthenic syndrome.
3 citations
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March 2019 in “European Journal of Dermatology” A specific gene mutation (Y449H in K10) was found in a patient with severe skin disorder.
2 citations
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January 1999 in “Dermatology” 29 citations
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October 2009 in “Pharmacology Biochemistry and Behavior” 8 citations
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June 2021 in “Frontiers in Medicine” This study reported that the combination of a 308-nm excimer lamp and 10% liquor carbonis detergens significantly improved scalp psoriasis symptoms compared to the excimer lamp alone, with more patients achieving 75% reduction in their Psoriasis Scalp Severity Index.
16 citations
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September 2016 in “Neuropharmacology” This study suggests that in an ex vivo rat glaucoma model, TSPO activation is involved in Allopregnanolone synthesis and may help prevent retinal damage, with TSPO agonists as potential therapeutic agents.
249 citations
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April 2002 in “The FASEB journal” This study provides evidence that human skin contains genes and enzymes necessary for producing serotonin and melatonin.
August 2026 in “International Journal of Developmental Neuroscience” In this report, researchers describe a 13-month-old with neurodevelopmental disorder NEDESBA, confirming a TRAPPC4 gene mutation as the cause after excluding biotinidase deficiency, highlighting the importance of molecular testing for accurate diagnosis in overlapping metabolic and genetic conditions.
18 citations
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June 2016 in “Brain Research” Increasing TSPO in the brain may help improve memory problems.