November 2023 in “JEADV Clinical Practice” In this study, adults with severe alopecia areata experienced greater improvements in hair regrowth, health-related quality of life, and reduced anxiety and depression symptoms after 36 weeks of treatment with baricitinib compared to placebo.
August 2023 in “International Journal of Women's Dermatology” In this study, a case of a 70-year-old woman with central centrifugal cicatricial alopecia showed that using a high-quality hair prosthesis improved her quality of life and mood, as measured by PHQ-9 and Skindex-29 scores, though such wigs are rarely covered by insurance.
This thesis presents the development of the Breast Utility Instrument (BUI), a new tool for assessing health-related quality of life specifically in breast cancer patients.
4 citations
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August 2019 in “Actas Dermo-Sifiliográficas” This study evaluated the Spanish version of the Hair Specific Skindex-29 questionnaire and found it sensitive to changes in health-related quality of life among women with female-pattern hair loss.
April 2018 in “Journal of Investigative Dermatology” This study suggests that for dermatomyositis patients with minimal skin disease activity, further improvement in cutaneous symptoms may not translate into better quality of life, highlighting a need to revise trial endpoints.
December 2013 in “Praxis medica” In this study, a strong correlation was found between the scores of two dermatology-specific quality of life instruments, DLQI and Skindex-16, suggesting they can provide complementary insights for assessing patients with skin diseases.
67 citations
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March 2021 in “Dermatology and Therapy” This review discusses the substantial impact of alopecia areata on patients' health-related quality of life, highlighting issues such as personality changes, emotional and social difficulties, and a common occurrence of alexithymia, and emphasizes the need for more specific assessment tools.
21 citations
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January 1988 in “Stress Medicine” This review discusses the developmental and psychological significance of skin and emphasizes the need for considering stress effects when evaluating and treating psychocutaneous diseases, without reporting new clinical results.
47 citations
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December 2016 in “Scientific Reports” This study found that women with PMS were more likely to use suppression rather than reappraisal for emotion regulation, and increased suppression was linked to higher skin conductance levels in these women.
19 citations
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January 2013 in “Journal of Cutaneous Medicine and Surgery” This study found that patients with alopecia areata exhibit a stronger deficiency in coping with stress compared to those with androgenetic alopecia and controls, suggesting a psychosomatic component to the condition.
May 2018 in “Actas Dermo-Sifiliográficas” This study validated a Spanish version of the Hair Specific Skindex 29 scale for assessing quality of life in women with female androgenetic alopecia, showing similar psychometric properties to the original.
May 2026 in “Research Square” Children with alopecia areata often face more stress and depression, especially related to separation, which can affect their condition.
May 2026 in “Research Square” In this study, researchers found that chemotherapy-induced alopecia counseling and resource access are insufficient and influenced by socioeconomic factors such as employment, income, and education, underscoring the need for standardized education and improved resource availability to address disparities.
222 citations
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October 1993 in “Journal of The American Academy of Dermatology” This study found that androgenetic alopecia causes significant psychological distress, particularly in women, who exhibit a more negative body image and less adaptive functioning compared to controls.
185 citations
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August 2005 in “Autoimmunity Reviews” This review discusses alopecia areata as a model for studying tissue-directed autoimmune diseases and reports no new clinical findings.
41 citations
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October 2000 in “Dermatologic clinics” This paper reviews hair structure and damage from grooming and cosmetic exposure but reports no new clinical findings; it suggests collaboration between dermatologists and cosmetic chemists to improve hair care products.
40 citations
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February 2013 in “American Journal of Clinical Dermatology” This study found that people with androgenic alopecia, particularly women, are more prone to anxiety and depression, often adopting avoidant coping strategies, which are linked to emotional and psychological impacts rather than clinical severity.
29 citations
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December 2022 in “Dermatology and Therapy” This study reported that patients with alopecia areata experienced significant increases in work productivity loss and activity impairment due to worsening emotional symptoms, highlighting a need for better treatments.
24 citations
,
August 2005 in “Health and Quality of Life Outcomes” This study observed that women aged 63 with androgenetic alopecia had higher insulin resistance and more role limitations due to physical health compared to those with normal hair.
9 citations
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March 2018 in “Actas Dermo-Sifiliográficas” This study found that the Spanish version of the Hair Specific Skindex 29 (HSS29) is a reliable and valid tool for assessing the quality of life impact of female androgenetic alopecia.
4 citations
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December 2020 in “Neuropsychiatric Disease and Treatment” In this study, body dysmorphic disorder symptoms in dermatological patients were strongly linked to psychiatric issues and reduced quality of life, particularly among those with unclassified dermatoses.
January 2026 in “Behavioral Sciences” In this observational study, among 135 Italian outpatients with alopecia areata, OCD symptoms were prevalent in 18.5%, and emotional distress was found in 20.7%, with emotional distress mediating the relationship between illness perceptions and OCD symptomatology.
63 citations
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February 2024 in “BMC Psychology” This study reports that emotion recognition technology integrated with intelligent devices is advancing applications to support emotion recognition and interventions, though further research is needed for effective use in dynamic or complex environments.
March 2024 in “Healthcare” In this study, women with androgenetic alopecia underwent stem cell treatment, which led to significant improvements in sexual arousal and satisfaction, psychological health, and environmental quality of life, but not in physical health or social relationships after six months.
2 citations
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November 2023 in “Global Advances in Integrative Medicine and Health” In this study, the authors reported preliminary evidence that programs combining nutrition and exercise interventions can significantly reduce BMI and LDL levels, suggesting these elements are important for lifestyle modification.
April 2023 in “Journal of the American Psychoanalytic Association” This review explores the emotional and psychoanalytic significance of male pattern hair loss through four perspectives but reports no new clinical findings.
October 2023 in “The Open public health journal” This study explored how alopecia impacts the socio-emotional lives and daily adaptation of women, finding that while not life-threatening, alopecia initially affects how they adjust to daily routines and perceive social and partner relationships.
105 citations
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March 2006 in “Human reproduction” This study found that metformin treatment improved health-related quality-of-life, emotional well-being, and sexual satisfaction among women with PCOS, correlated with weight loss and menstrual cycle normalization.
June 2025 in “British Journal of Dermatology” In this systematic review, the authors found that hair loss in women causes significant psychological distress, with supportive interventions like cognitive behavioral therapy and cosmetic solutions helping to reduce anxiety, improve coping, and enhance quality of life.
September 2025 in “Journal of Cosmetic Dermatology” This review found that hair transplantation can positively impact self-esteem and emotional well-being when patients are properly screened for psychological risk factors, but inadequate screening may lead to dissatisfaction or worsened mental health.