4809 citations
,
January 2004 in “Fertility and Sterility” This review discusses polycystic ovary syndrome, emphasizing its broad range of manifestations and associations with risks like type 2 diabetes and cardiovascular events, but reports no new clinical results.
4025 citations
,
December 2003 in “Human Reproduction” This review discusses the evolution of diagnostic criteria for polycystic ovary syndrome and emphasizes its association with various metabolic and cardiovascular risks, but it provides no new research findings.
1 citations
,
January 2001 in “Drug and therapeutics bulletin” This review discusses the management of polycystic ovary syndrome in women and reports no new clinical results.
17 citations
,
May 2019 in “Diabetes and Metabolic Syndrome: Clinical Research and Reviews” This study found that fasting insulin levels are associated with increased cardiovascular and metabolic risk factors in women with polycystic ovary syndrome.
28 citations
,
April 2014 in “Hormones” This study found that increased serum A4A levels were associated with more severe polycystic ovary syndrome phenotypes and could be a useful marker for biochemical hyperandrogenemia.
29 citations
,
January 1998 in “Dermatology” This research reports that many acne patients have elevated androgen levels, contributing to a cycle that may lead to polycystic ovarian disease and potentially sterility.
April 2025 in “Journal of Investigative Dermatology” This study found that elevated luteinizing hormone levels were significantly associated with female pattern hair loss, and implicated LH/LHR signaling in the aging and damage of hair follicles.
9 citations
,
June 2014 in “European Journal of Obstetrics & Gynecology and Reproductive Biology” Blood AMH levels are higher in women with PCOS than in those with other similar conditions.
2 citations
,
January 2017 in “Iraqi journal of medical sciences” This study found that serum zinc levels were significantly decreased in obese women with polycystic ovary syndrome compared to their non-obese counterparts.
4 citations
,
May 2022 in “BMC Women's Health” This study found that elevated serum AMH levels can be a strong predictor for diagnosing PCOS among women of reproductive age, when used alongside the other Rotterdam criteria.
3 citations
,
January 2024 in “Revista da Associação Médica Brasileira” In this study, the authors reported that depression and anxiety are more prevalent in patients with polycystic ovary syndrome compared to healthy women, reinforcing the need for routine mental health screening in this population.
39 citations
,
August 2001 in “Clinical endocrinology” This study found that lean women with PCOS have a similar degree of tissue insulin resistance as obese women with PCOS, suggesting that insulin resistance may be a primary feature of the syndrome.
10 citations
,
May 2009 in “Cases Journal” This case study reports that a virilizing Leydig cell type ovarian tumor in a 40-year-old woman caused hyperandrogenism and virilization symptoms, which improved post-surgery.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This infographic reviews the pathophysiology and complications of PCOS, illustrating how genetic and environmental factors contribute to its development, and highlights associated metabolic and neuroendocrine effects.
February 2009 in “Journal of The American Academy of Dermatology” A man with Klinefelter syndrome had a leg ulcer that didn't heal well, even with treatment.
April 2019 in “Journal of the Endocrine Society” This case study highlights the late diagnosis of complete androgen insensitivity syndrome in a 31-year-old woman, emphasizing the psychological impact and need for individualized treatment guidelines.
August 2023 in “Journal of Clinical Medicine” This study found that metformin's effect on reducing prolactin levels is less pronounced in women with PCOS compared to control subjects, likely due to higher endogenous testosterone levels, despite improvements in insulin sensitivity in both groups after six months of treatment.
11 citations
,
January 2014 in “PubMed” This study found that patients with high androgen levels due to PCOS required more sessions of Nd-YAG laser therapy for hair reduction compared to those with normal or low hormone levels.
December 2024 in “Journal of Neonatal Surgery” In this study, researchers found that increased androgen levels, such as testosterone, and insulin resistance are strongly associated with more severe acne in adult women, along with a higher incidence of menstrual irregularities and PCOS characteristics.
September 2021 in “Journal of pharmaceutical research international” This study found that hirsutism patients had a strong correlation with polycystic ovary syndrome and elevated levels of certain hormones, such as 17-OHP and serum testosterone.
January 2016 in “AACE Clinical Case Reports” In this case report, an embryonal cell carcinoma of the testicle was associated with polycythemia and markedly elevated hormone levels without secondary sexual characteristics, which were restored after treatment.
July 2024 in “Reproductive health of woman” This study found that teenage girls born via assisted reproductive technologies displayed premature development of secondary sexual characteristics and elevated hormone levels, indicating late precocious puberty and androgen excess.
February 2026 in “South Asian Research Journal of Biology and Applied Biosciences” In this study, patients with alopecia areata had significantly higher levels of luteinizing hormone and follicle-stimulating hormone compared to healthy controls, suggesting a link between hormone levels and the disease.
3 citations
,
April 2017 in “Journal of Medical Science And clinical Research” In this study, acne was the most common skin manifestation among women with PCOS, significantly correlated with elevated LH levels and the LH:FSH ratio.
August 2025 in “Journal of Medical and Life Science” This case-control study in Missan Province, Iraq, found that married women with PCOS had higher rates of obesity and menstrual irregularities, along with elevated testosterone, LH, and insulin levels, compared to healthy controls, highlighting significant hormonal and metabolic complications.
July 2025 in “Indus journal of bioscience research.” This study found that women with polycystic ovary syndrome showed significant differences in clinical symptoms, hormone levels, and ovarian morphology compared to healthy controls, such as higher body mass index, menstrual irregularities, elevated luteinizing hormone, and polycystic ovarian morphology, suggesting these factors enhance diagnostic accuracy.
August 2025 in “Journal of Investigative Dermatology” Elevated luteinizing hormone contributes to female-pattern hair loss, and blocking certain channels may help prevent it.
June 2026 in “Biomolecules and Biomedicine” This study found that women with PCOS had higher levels of serum phoenixin isoforms, which correlated with reproductive and metabolic markers, suggesting these isoforms may have a potential diagnostic role.
February 2016 in “Evidence Based Women Health Journal (Online)” This study observed that women with polycystic ovarian syndrome had higher serum SRAGE levels compared to controls, but the difference was not statistically significant.
1 citations
,
July 2025 in “Middle East Fertility Society Journal” This study found that women with PCOS had significantly higher levels of several autoantibodies compared to healthy controls, suggesting a potential autoimmune component to PCOS that might aid in better disease characterization and personalized management.