20 citations
,
January 1997 in “Dermatology” This case report describes a 16-year-old with ectrodactyly-ED-clefting syndrome, where scarring alopecia with follicular involvement appeared during puberty, possibly due to anatomic hair abnormalities.
3 citations
,
June 2004 in “Työväentutkimus Vuosikirja” This article reviews the roles of several signaling pathways and molecules, including FGFs, Hh, Notch, TGF, and Wnt, in the development of teeth and hair follicles, but reports no new findings.
February 2016 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” This study reports a novel mutation in the TP63 gene associated with T and B cell lymphopenia in an EEC patient, suggesting that EEC diagnosis should include TREC assay and evaluation for immunodeficiency.
25 citations
,
September 2005 in “Journal of the American Academy of Dermatology” This study reported that Rapp-Hodgkin syndrome, AEC syndrome, and EEC syndrome are likely part of a single genetic disorder spectrum linked to mutations in the TP63 gene.
9 citations
,
August 2024 in “Australian Prescriber” This review highlights that pharmacotherapy for polycystic ovary syndrome should address individual patient concerns, with metformin beneficial for reducing weight and metabolic risk, and lifestyle modifications also important.
June 2025 in “Veterinární Medicína” In this veterinary study, uveodermatological syndrome in dogs was reported to cause skin depigmentation, alopecia, and eye issues such as granulomatous panuveitis, which leads to complications like cataracts and glaucoma; while immunosuppressive therapy often helps, recurrence and treatment side effects challenging therapeutic management.
40 citations
,
January 2010 in “International Journal of Trichology” This review discusses the diagnostic criteria and guidelines for managing loose anagen syndrome and differentiating it from non-scarring alopecias, but it reports no new clinical results.
21 citations
,
May 2021 in “Patient education and counseling” This study explored the challenges faced by both clinicians and women with polycystic ovary syndrome in managing the condition, highlighting issues with treatment options, misinformation, and differing expectations in care.
4 citations
,
January 2022 in “Open Health” This article discusses the challenges in treating PCOS, highlights the role of lifestyle interventions, and notes the lack of effective treatment beyond symptomatic management for this common reproductive health issue.
December 2025 in “Insights-Journal of Health and Rehabilitation” This study assessed the impact of Polycystic Ovarian Syndrome on married women's quality of life, finding significant negative effects on psychological well-being, fertility-related concerns, and body image, underscoring the need for comprehensive and culturally sensitive interventions.
November 2025 in “Cureus” This review discusses the link between PCOS and acne, highlighting the roles of hyperandrogenism and insulin resistance, but it reports no new clinical findings.
This study evaluated machine-learning models to predict PCOS among reproductive-aged women in Bangladesh, finding that the XGBoost model achieved high accuracy (99.63%) and effectiveness, particularly when prioritizing clinical features over psychological ones in the predictive process.
July 2025 in “Journal of Pharmacognosy and Phytochemistry” This review explores the potential benefits of plant-based diets, herbal remedies, and phytochemicals for managing PCOS, suggesting they may help regulate menstrual cycles, improve metabolic parameters, and reduce androgen levels, offering a promising, holistic approach to treatment.
May 2025 in “International Journal of Clinical Obstetrics and Gynaecology” This article reviewed literature from 2013-2023 and found that while varied treatment options for PCOS exist, managing the condition holistically, including lifestyle changes and gastric bypass surgery, can significantly improve symptoms and quality of life without worsening side effects.
January 2025 in “Directory of Open access Books (OAPEN Foundation)” This book reviews the symptoms, diagnosis, and treatments for Polycystic Ovary Syndrome, providing a comprehensive exploration but reports no new clinical results.
46 citations
,
October 2009 in “Archives of Dermatology” This study found that loose anagen hair syndrome is a common form of alopecia in young girls, typically presenting with thin, sparse hair and usually confirmed by a hair-pull test.
31 citations
,
December 2010 in “Journal of the American Academy of Dermatology” This study reports that structural abnormalities in the inner root sheath of hair follicles may cause the hair shaft to be loosely attached in patients with loose anagen hair syndrome.
35 citations
,
August 2010 in “The American journal of pathology” This study reports that hypomorphic alleles of the Ass1 gene in mice resemble human CTLN1, providing a potential model for preclinical studies and indicating that standard treatments for CTLN1 can rescue phenotypes.
6 citations
,
May 2000 in “Pediatric Dermatology” This article discusses a case study supporting the reclassification of KID syndrome as an ectodermal dysplasia, introducing a potential treatment combination that may alleviate symptoms in affected patients.
44 citations
,
January 2005 in “Dermatology” This article reviews the clinical and diagnostic features of hair shaft disorders, emphasizing the role of structured patient assessments and the avoidance of hair trauma, but reports no new results.
11 citations
,
May 2011 in “World Journal of Pediatrics” The document emphasizes the importance of correctly identifying and classifying genetic hair disorders to help diagnose related health conditions.
30 citations
,
May 2004 in “Journal der Deutschen Dermatologischen Gesellschaft” This review proposes a classification system for childhood hair loss based on clinical appearance, age of onset, and associated symptoms, but reports no new clinical results.
3 citations
,
January 2018 in “Reproduction, Fertility and Development” This study concluded that cyproterone acetate alone produced antiandrogenic effects on the female gerbil prostate, while ethinyloestradiol alone stimulated estrogenic activity, and their combination led to prostatic lesions.
26 citations
,
December 2011 in “Journal of Investigative Dermatology” This review discusses major advances in understanding inherited hair diseases through genetic research and reports no new clinical results; the authors emphasize the potential for new preventive and therapeutic tools.
6 citations
,
December 2024 in “BMC Women s Health” This study found that a lifestyle promotion program led to significant weight loss, waist reduction, and improved menstrual regularity and acne symptoms in adolescents with PCOS, while also promoting similar benefits in non-PCOS adolescents.
3 citations
,
July 2025 in “Reproductive Biology and Endocrinology” This study found that chromium, inositol, and Omega-3 are beneficial for improving lipid profiles in women with PCOS, and various supplements help alleviate other symptoms.
2 citations
,
May 2023 in “Current Nutrition Reports” This review summarizes various nutritional approaches and supplements, such as the Mediterranean and ketogenic diets and probiotics, as potential strategies to improve polycystic ovary syndrome symptoms, reporting no new clinical results.
1 citations
,
July 2023 in “Frontiers in Immunology” This review highlights the role of chronic stress, oxidative stress, and immune processes in the development of Hashimoto’s thyroiditis and polycystic ovary syndrome, emphasizing the potential of antioxidants in their treatment based on the existing literature.
December 2025 in “Journal of Education Health and Sport” This review discusses the potential of green tea, especially its catechin EGCG, in reducing PCOS symptoms like insulin resistance and androgen levels, but reports no new clinical results and emphasizes the need for further research.
December 2025 in “International Journal of Research in Dermatology” This consensus highlights that addressing nutritional and endocrine deficiencies through lifestyle modifications, nutritional support, and medical interventions is crucial for managing hair loss associated with endocrine and gynecological disorders, emphasizing the need for a multidisciplinary approach involving dermatologists, nutritionists, endocrinologists, and gynecologists.