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Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Some Middle Eastern plants may help treat diabetes and could be alternatives to current drugs, but more research is needed.

Ziziphus jujuba Mills may have health benefits, but more research is needed to confirm its safety and effectiveness.

Some newly made compounds are promising for treating enlarged prostate, hair loss, viruses, and prostate cancer, and might be better than current drugs.

Common Black hair care products may affect hormone levels and potentially impact health, especially in reproductive and metabolic areas.

Spironolactone harms fish reproduction and is more potent in fish than invertebrates, needing environmental monitoring.

The leaves of Platycladus orientalis have potential health benefits but require more research for safety and understanding how they work.

Using computers to analyze drugs can find new uses for them, but actual experiments are needed to confirm these uses.

New androgen receptor modulators show promise for treating diseases like prostate cancer and muscle wasting.

Rosemary's antioxidant content changes with the climate and season.

Small molecule IM boosts hair growth by changing stem cell metabolism.

Juniperus plants contain compounds with potential for developing various medical treatments.

Certain drugs increase calcium levels in cancer cells by triggering internal calcium release.

Thyroid receptor agonists may treat male pattern baldness without harmful side effects.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.

Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.

New patents show progress in developing drugs targeting the Wnt pathway for diseases like cancer and hair loss.

CBG may help with various medical conditions but needs more human research to confirm safety and effectiveness.

Dutasteride may help reduce brain plaque linked to Alzheimer's by affecting cell energy structures and waste removal.

Eclipta alba extract may help treat obesity by blocking fat cell formation and lowering blood lipid levels.

Changing the 6-position on benzopyran molecules affects insulin release, with some compounds showing strong inhibitory effects.

Activating TRPV3 channels stops hair growth by killing hair follicle cells.

Some curcumin-like compounds can effectively and safely block the enzyme linked to hair loss and other conditions related to male hormones.

Analog 23 is a promising compound for prostate cancer treatment.

Maidenhair fern extract reduced anxiety and depression in rats and may work due to its antioxidant and anti-inflammatory properties.

New compounds similar to cromakalim were less effective at inhibiting insulin release but improved in solubility and one acted as a calcium entry blocker, not a potassium channel opener.

Ecklonia cava extract can reduce the damage and stress caused by hair dye.

Elephantopus scaber has many health benefits, including antibacterial, antifungal, anticancer, and antioxidant properties.

The anti-viral drug Elvitegravir may protect brain cells from damage related to neurodegenerative diseases.