February 2023 in “Clinical, Cosmetic and Investigational Dermatology” Higher leptin and lower vitamin D levels may contribute to male pattern baldness.
December 2023 in “Research Square (Research Square)” People with Down syndrome have higher rates of certain immune-related conditions and need special medical attention.
69 citations,
September 2006 in “Human Reproduction” Women with PCOS have fewer activated T cells in their ovarian follicles, which might affect fertility.
November 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin organoids with NCSTN mutation show changes in hair follicle development and higher inflammation, key features of Hidradenitis Suppurativa.
9 citations,
May 2014 in “BMC medical genetics” A woman with a unique syndrome similar to TRPS has a genetic change near the TRPS1 gene, affecting its regulation.
5 citations,
December 2016 in “International journal of biometeorology” Bright light during the day doesn't change most human clock genes but may slightly increase Rev-erb-ß.
10 citations,
October 2016 in “Monoclonal antibodies in immunodiagnosis and immunotherapy” Researchers created specific antibodies that detect a protein important in development and various conditions, and can be used for research and diagnosis.
77 citations,
December 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” Human skin cells produce proenkephalin, which changes with environmental factors and skin diseases.
October 2023 in “Dermatological reviews” Fibroblast-derived growth factors and exosomes can significantly improve skin aging.
17 citations,
January 2020 in “Skin appendage disorders” Certain diets may help with hair growth in people with different types of hair loss.
12 citations,
January 2010 in “European Journal of Dermatology” Norgalanthamine from Crinum asiaticum may help hair grow.
163 citations,
November 2003 in “Journal of Investigative Dermatology” Low iron levels may be linked to some types of hair loss in women.
31 citations,
May 2019 in “Nature communications” Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.
72 citations,
December 2012 in “Expert Opinion on Drug Delivery” Niosomes are promising for skin drug delivery, offering benefits like improved drug penetration and stability.
19 citations,
June 2008 in “Journal of Investigative Dermatology” HPV genes in mice improve ear tissue healing by speeding up skin growth and repair.
96 citations,
December 2002 in “Experimental dermatology” NGAL indicates abnormal skin cell differentiation.
July 2022 in “Journal of Investigative Dermatology” PRP may help treat hair loss, but results vary.
August 2013 in “Nature Reviews Drug Discovery” New treatments may restore cancer-blocking proteins, slow prostate cancer, identify drug targets, and potentially regrow hair.
August 2013 in “Nature Reviews Drug Discovery” A protein called FGF9 helps regenerate hair follicles in mice after skin damage, and increasing FGF9 could potentially help human hair growth.
August 2013 in “Nature Reviews Drug Discovery” New treatments for cancer and skin disorders show promise in disrupting harmful cell interactions and promoting hair growth.
August 2013 in “Nature Reviews Drug Discovery” New cancer treatments show promise in reducing tumor growth and improving skin regeneration in mice.
233 citations,
July 1997 in “PubMed” High levels of ornithine decarboxylase can cause tumors in mouse skin.
April 2023 in “Journal of Investigative Dermatology” A protein called MPZL3 in mitochondria slows down hair growth and could be a target for treating hair growth disorders.
5 citations,
August 2014 in “Australasian journal of dermatology” Sorafenib can cause delayed skin problems, so patients need careful monitoring.
Aging disrupts skin repair and stress responses, but exercise-related IL-15 improves wound healing and skin health in older skin.
August 2012 in “Nature Cell Biology” A pathway helps maintain long telomeres in both stem and cancer cells.
16 citations,
July 2020 in “Psychoneuroendocrinology” People with Parkinson's disease have higher levels of cortisone in their hair, which may indicate chronic stress hormone dysfunction.
April 2019 in “Journal of Investigative Dermatology” Non-coding RNA boosts retinoic acid production and signaling, aiding regeneration.
August 2012 in “Nature Cell Biology” The tumor suppressor BRCA2 helps in cell division by bringing key proteins to the area where cells split.
January 2024 in “Elsevier eBooks” Increasing regulatory T cells may help treat alopecia areata by reducing autoimmunity and promoting hair growth.