research Incomplete Recovery of Erectile Function in Rats After Discontinuation of Dual 5-Alpha Reductase Inhibitor Therapy
Rats had lasting erectile problems after stopping a certain medication.
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270-300 / 1000+ results research Topical and Nutricosmetic Products for Healthy Hair and Dermal Anti-Aging Using Dual-Acting Plant-Based Peptides, Hormones, and Cannabinoids
Plant-based products can improve hair and skin health without harmful side effects.
research Medical, Dental, and Dual-Degree Oral-Maxillofacial Signatures: What Have I Seen Over the Past 22 Years?
The document compares oral-maxillofacial surgery training in Thailand, France, and Germany, highlighting differences in curriculum focus and medical rotations.
research Marked Suppression of Dihydrotestosterone in Men with Benign Prostatic Hyperplasia by Dutasteride, a Dual 5α-Reductase Inhibitor
Dutasteride more effectively lowers DHT levels in men with enlarged prostates than finasteride.
research Discovery and Clinical Development of Dutasteride, a Potent Dual 5α-Reductase Inhibitor
Dutasteride effectively treats benign prostatic hyperplasia and may reduce prostate cancer risk.
![Synthesis and Activity of 8-Substituted Benzo[c]quinolizin-3-ones as Dual Inhibitors of Human 5α-Reductases 1 and 2](/images/research/efc54340-66d6-4f27-9930-045ac023f903/small/15248.jpg)
research Synthesis and Activity of 8-Substituted Benzo[c]quinolizin-3-ones as Dual Inhibitors of Human 5α-Reductases 1 and 2
New compounds were made that effectively block enzymes related to prostate issues and hair loss.
research Non-Clinical Safety Evaluation and Risk Assessment of Aleglitazar, a Dual PPAR α/γ Agonist, and Its Major Human Metabolite
Aleglitazar and its major metabolite are safe enough to proceed to Phase 3 clinical trials.
research A Combination Therapy for Androgenic Alopecia Based on Quercetin and Zinc/Copper Dual-Doped Mesoporous Silica Nanocomposite Microneedle Patch
The microneedle patch with quercetin, zinc, and copper effectively promotes hair regrowth for androgenic alopecia.
research A Combination Therapy for Androgenic Alopecia Based on Quercetin and Zinc/Copper Dual-Doped Mesoporous Silica Nanocomposite Microneedle Patch
A new patch that releases quercetin, copper, and zinc ions under the skin can effectively treat hair loss by promoting hair follicle regeneration.
research The Effect of Cilostazol, a Phosphodiesterase 3 (PDE3) Inhibitor, on Human Hair Growth with Dual Promoting Mechanisms
Cilostazol helps hair grow by making hair root cells grow faster and changing growth factor levels.
research Design, Synthesis and Biological Evaluation of Novel 3-Oxo-4-Oxa-5α-Androst-17β-Amide Derivatives as Dual 5α-Reductase Inhibitors and Androgen Receptor Antagonists
New compounds were made that are promising for prostate cancer therapy.
research Testosterone Target Therapy: Focus on Immune Response, Controversies, and Clinical Implications in Patients with COVID-19 Infection
Testosterone may have a dual role in COVID-19, potentially worsening outcomes in men, and testosterone therapy could help some patients, but more research is needed.
research Development of Novel Indole-Based Bifunctional Aldose Reductase Inhibitors and Antioxidants as Promising Drugs for the Treatment of Diabetic Complications
New indole-based compounds, particularly cemtirestat, show promise as dual-function drugs for diabetic complications.
research Dihydrotestosterone and the Concept of 5-Alpha-Reductase Inhibition in Human Benign Prostatic Hyperplasia
Blocking the enzyme that turns testosterone into DHT can safely and effectively treat enlarged prostate.
research Sulfatase Inhibitors: A Patent Review
The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.
research Clinical Application of 5α-Reductase Inhibitors
5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.
research Bone Mineral Density in Patients with Alopecia Areata Treated with Long-Term Intralesional Corticosteroids
Patients treated with long-term intralesional corticosteroids for alopecia areata should be monitored for bone density changes and advised on osteoporosis prevention.
research Peri-Xanthenoxanthene (PXX): A Versatile Organic Photocatalyst in Organic Synthesis
PXX is an effective and affordable photocatalyst for creating new chemical bonds in organic synthesis.
research Bone Mineral Density Is Unaltered in Women with Polycystic Ovary Syndrome
Women with PCOS have similar bone density to healthy women, but those who are obese have higher bone density at some body sites.
research Family Planning 2011: Better Use of Existing Methods, New Strategies, and More Informed Choices for Female Contraception
The conclusion is that there is a high demand for new contraceptives that provide both pregnancy prevention and protection against STIs, along with additional health benefits.
research A New Era of 5α-Reductase Inhibitors for Androgenetic Alopecia
New drug dutasteride effectively treats hair loss, but use cautiously due to potential sexual side effects.
research Multi-Targeted Non-Invasive Photoceutical Therapeutic Approach for Combat and Traumatic Soft Tissue Injuries
Light therapy can help heal soft tissue injuries and reduce pain and inflammation.
research Reactive Oxygen Species: Beneficial Companions of Plant Developmental Processes
Reactive oxygen species (ROS) help control plant growth and development.
research Protoporphyrin IX: The Good, the Bad, and the Ugly
Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.
research Local Heroes or Villains: Tissue-Resident Memory T Cells in Human Health and Disease
Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.
research Dupilumab And Alopecia: A Janus Effect
Dupilumab can both heal and cause hair loss.
research Hair Cluster Detection Model Based on Dermoscopic Images
The new model detects hair clusters more accurately and efficiently, helping with early hair loss treatment and diagnosis.
research UV Radiation, Vitamin D, and Epidermal Carcinogenesis
Vitamin D may help protect against nonmelanoma skin cancer.
research The Senescence–Stemness Alliance: A Cancer-Hijacked Regeneration Principle
Cancer can hijack the body's cell repair system to promote tumor growth, and targeting this process may improve cancer treatments.
research Removing All Obstacles: A Critical Role for p53 in Promoting Tissue Renewal
The gene p53 is crucial for removing damaged cells to allow for healthy tissue renewal.