October 2023 in “Case reports in dermatological medicine” In this case report, a 45-year-old Jordanian woman was diagnosed with Clouston syndrome, an autosomal-dominant disorder characterized by alopecia and nail dystrophy due to a mutation in the GJB6 gene, though she lacked the typical palmoplantar keratoderma.
18 citations
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February 2006 in “Brain & development” This case study reports successful treatment of a 19-year-old with Satoyoshi syndrome using a combination of carbamazepine, methotrexate, prednisolone, and sex-steroids, improving muscle spasms, alopecia, and quality of life.
33 citations
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February 2011 in “International Journal of Dermatology” This study observed that orange spots and dystrophic hairs on trichoscopy may aid in diagnosing scalp sarcoidosis.
April 2025 in “Dermatology Practical & Conceptual” This study found that erosive pustular dermatosis of the scalp is often misdiagnosed as squamous cell carcinoma, highlighting the importance of biopsy for accurate diagnosis.
6 citations
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July 2024 in “Heliyon” This study examined the evolutionary and functional homology of steroid 5α-reductase and DET2 proteins, identifying protists as a common ancestor, and discovered a new subclass DET2-like in plants, potentially involved in polyprenol reduction.
January 2022 in “International journal of dermatology and venereology” This case study reports a 36-year-old man with KID syndrome caused by an N14Y GJB2 mutation, expanding the mutation spectrum of this condition in the Chinese population.
25 citations
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October 2018 in “Journal of The American Academy of Dermatology” This study concluded that erosive pustular dermatosis of the scalp may be a type of spongiotic, pustular superficial folliculitis, sharing similarities with other neutrophilic dermatoses.
3 citations
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July 2020 in “International Journal of Molecular Sciences” This study reported that molecules from Zebrafish embryo cell differentiation can counteract neurodegeneration, regenerate tissues, and potentially reverse hair follicle damage in androgenetic alopecia.
5 citations
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April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study reports on an ongoing Phase I/IIa clinical trial of ex vivo gene therapy for treating severe Recessive Dystrophic Epidermolysis Bullosa, involving six adult participants with COL7A1 mutations resulting in deficient type VII collagen production.
January 2022 in “Figshare” This study suggests that stress-associated hair loss may occur due to increased androgen receptor expression and activity induced by dexamethasone in human and mouse dermal papilla cells.
April 2024 in “BMB Reports” This study used Cisd2 knockout mice models and found that these mice display premature aging characteristics and an increase in dysfunctional neutrophils, suggesting Cisd2's role in calcium homeostasis and neutrophil function via interactions with Calnexin and SERCA.
56 citations
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January 1999 in “The Analyst” This study used gas chromatography-mass spectrometry to simultaneously quantify androstenedione, dihydrotestosterone, dehydroepiandrosterone, testosterone, androsterone, etiocholanolone, progesterone, and pregnenolone in human hair, detecting differences in steroid concentrations between male and female samples.
13 citations
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February 2012 in “International Journal of Dermatology” This case report identifies a novel nonsense mutation in the CDH3 gene associated with hypotrichosis and juvenile macular dystrophy.
March 2024 in “Frontiers in genetics” This study used genomic analysis to reveal moderate genetic diversity, minimal inbreeding, and specific genes under positive selection in Xiangdong black goats, highlighting their unique adaptation traits and potential for breeding and conservation.
19 citations
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March 2016 in “Frontiers in Plant Science” This study identified that spermidine-mediated activation of eIF5A by hypusination plays a significant role in Arabidopsis thaliana growth, flowering time, stress adaptation, and development, including changing root and aerial architecture.
4 citations
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September 2024 in “BMC Cancer” In this prospective phase II clinical trial, researchers are investigating whether adding dutasteride to combined androgen blockade can improve the response rate and clinical outcomes for patients with androgen receptor-positive recurrent or metastatic salivary duct carcinoma.
August 2015 in “International Journal of Genetics and Molecular Biology” This study found that specific Y-chromosome alleles may influence susceptibility to prostate cancer in Iraqi males, suggesting their potential use in screening for the disease.
10 citations
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September 2022 in “Animals” This research identified 18 significant SNPs and several candidate genes associated with udder conformation traits in Holstein cattle, providing insights into their genetic architecture.
In this study, a two-year-old black Dobermann pinscher with progressive dorsal hair loss and folliculitis showed a partial response to prolonged omega-3/omega-6 fatty acid treatment.
5 citations
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February 2019 in “PloS one” This study found that structural defects in the hair shafts of sighthounds with bald thigh syndrome are related to a downregulation of genes and proteins essential for hair shaft formation.
January 2024 in “Indian Journal of Psychiatry” This study found that precision 40Hz gamma-transcranial alternating current stimulation significantly improved negative and cognitive symptoms in patients with schizophrenia compared to a sham group, suggesting promising potential for this neuromodulation technique in treating these symptoms.
2 citations
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August 2014 in “Journal of the American Academy of Dermatology” This case report details a Taiwanese woman with scleredema adultorum and diabetes mellitus experiencing loss of eccrine glands, which led to frequent heat strokes and anhidrosis despite treatment.
August 2025 in “DS Reviews of Research in Life Sciences” In this study, women with polycystic ovary syndrome showed significantly higher levels of DHEA, IL-6, and TNF-α compared to healthy controls, indicating a possible link between these biomarkers and PCOS.
February 2025 in “Iraqi Journal of Science” This study found that women with polycystic ovary syndrome had significantly higher serum lactate dehydrogenase levels and lower levels of cortisol, dopamine, zinc, and vitamin D3 compared to healthy controls.
13 citations
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July 2019 in “Pediatric dermatology” This review addresses dermatologic health disparities in sexual and gender minority adolescents, highlighting the need for improved pediatric dermatologic care; it does not report new clinical results.
9 citations
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August 2023 in “Molecules” This study found that the peptides RMYYY and VMYMI displayed stronger binding energy and more frequent interactions with HPGDS compared to the native inhibitor, suggesting potential as future therapeutic drugs.
13 citations
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February 2016 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” In this study, researchers observed that the absence of the vitamin D receptor or its ligand-activated transcription in mice did not affect glucose homeostasis or gene expression in islets.
In a case report, this study identified a new genetic variant in a six-year-old girl from Saudi Arabia with hypotrichosis and juvenile macular dystrophy, expanding the understanding of the genetic spectrum of this rare condition in the region.
1 citations
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August 2019 In this study, researchers developed a pemphigus mouse model expressing anti-Desmocollin 3 antibodies and found it mimicked atypical pemphigus with distinct pathological features compared to the standard Desmoglein 3 model.