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This study designed a novel model for 5a-reductase enzyme inhibitors using pharmacophore and 3D QSAR techniques, potentially allowing for improved prediction and development of drug therapies targeting benign prostatic hyperplasia.

This review discusses drug repurposing for various conditions, including cancer and COVID-19, highlighting ongoing trials with potential repurposed drugs but provides no new clinical results.

This study improved a hair analysis method to estimate the days of continuous ingestion of hay-fever medicines, with an average error of about 2 days from actual ingestion.

This chapter reviews the hair follicle's role in drug and chemical penetration through the skin but does not present new experimental findings.

This study underscores the use of hair analysis in forensic toxicology, highlighting its ability to detect drugs such as opioids and amphetamines, while noting limitations related to hair growth cycles, result interpretation, and cost of techniques.

This article reviews the use of hair analysis in forensic and environmental toxicology for detecting potentially toxic elements and drugs, but it reports no new research findings.

This study introduces a new Drug Efficacy Index to predict the effectiveness of various Ayurvedic hair care formulations and modern medicines.

This study conducted molecular docking and ADME property analysis on 144 newly designed isatin analogs, suggesting they exhibit lead-like properties for targeting EGFR enzymes.

This review discusses various adverse drug reactions affecting the skin, hair, and nails, emphasizing the importance of recognizing and reporting these reactions but reports no new clinical findings.

This article discusses the development and testing of comprehensible over-the-counter drug product labels, highlighting the need for improved consumer understanding and calling for further research on label design.

This study found that certain molecular quantum descriptors can be directly correlated with the biological activity of benzo[c]quinolizin-3-ones, potentially aiding in the identification and design of active compounds.

The researchers reported that the rat Hershberger assay reliably detected endocrine-disrupting effects of finasteride, procymidone, and 17α-methyltestosterone, validating the assay's sensitivity for identifying hormonal activity.

In this in silico study, researchers found that the hair follicle's contribution to dermal permeability of small molecules varies with the lipophilic and hydrophilic properties of substances, highlighting the need for careful characterization of substances filling the follicular route when interpreting experimental permeability data.

This study used data mining of the FDA Adverse Event Reporting System to analyze drug-induced pruritus, revealing differences in gender, age, and weight among cases, and identified ophthalmic drugs and systemic antibacterials as common triggers, contributing to potential prevention and treatment strategies for pruritus.

This chapter reviews current and future strategies for identifying ligands and functions of orphan G protein-coupled receptors, but it reports no new experimental results.

This study developed a deep learning-based method that identified 3,620,516 potential drug-disease associations, suggesting a promising tool for large-scale virtual screening in drug research.

This study describes a new LC-MS/MS method for analyzing Finasteride and Tadalafil, demonstrating system suitability, linearity, and accuracy in pharmacokinetic studies in rats, aligning with USFDA guidelines.

This study found that the WNMFDDA model effectively predicts drug-disease associations, achieving high accuracy in cross-validation and confirming most candidate associations through existing databases.

This review highlights that human hair is a valuable biological matrix for clinical and toxicological analyses, demonstrating its applicability in detecting various active substances from different pharmacological classes.

This study developed a new, simple, and economical RP-TLC method with densitometry that is suitable for routine analysis of finasteride in tablet dosage form, meeting analytical validation criteria.

This review discusses the pharmacological properties and analytical methods for determining fluconazole but reports no new experimental findings.

This study developed a validated method to detect prohibited drugs in dietary supplements, finding minoxidil, triaminodil, and finasteride in some samples.

This study demonstrated that human plucked hairs can be used as a valuable biomarker to evaluate the pharmacodynamic responses of various chemotherapy agents ex vivo, supporting their potential use for assessing oncology drug target engagement prior to clinical studies.

This study discusses a hypothesis for repurposing non-cancer drugs and combining micronutrients to target cancer and cancer stem cells with fewer side effects, suggesting a potential new approach for more effective cancer therapy.

This study reports that drug repurposing for COVID-19 has had mixed results, with success for some drugs but a lack of clinical efficacy for others, highlighting the need for improved preclinical profiling and a standardized drug development platform for future antiviral treatments.

This study found that the combination of Stemoxydine® and Resveratrol improved hair density in women with Female Pattern Hair Loss.

This study developed a method using ultra-performance liquid chromatography and mass spectrometry to detect illegal substances in hair loss prevention cosmetics, revealing that some products contained high levels of minoxidil and finasteride, posing safety risks.

This in vitro study found that opiate diffusion was more pronounced in damaged hair fibers than in undamaged ones, with high opiate concentrations detected in fiber centerpieces.