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This study discusses a hypothesis for repurposing non-cancer drugs and combining micronutrients to target cancer and cancer stem cells with fewer side effects, suggesting a potential new approach for more effective cancer therapy.

This review outlines drug repurposing as an efficient, low-cost strategy to identify new uses for existing drugs, highlighting various computational and experimental approaches as well as publicly available databases to aid in personalized pharmacotherapy.

This study developed ultrasound-responsive sutures that generate reactive oxygen species to kill bacteria without antibiotics, showing over 80% bacterial reduction and promoting healing in a rat model, though more validation is needed.

This study developed a method for designing peptide-based PROTAC drugs using advanced AI models, successfully identifying peptides that bind to specific receptors and incorporating them into a potential transdermal treatment for androgenetic alopecia.

The authors describe drug repurposing as a promising strategy for finding new uses for existing drugs, noting it is efficient, cost-effective, and poses lower risks than traditional drug discovery processes, potentially aiding in the treatment of rare and difficult-to-treat diseases.

This review reports that biomaterial-based drug delivery systems show promise in overcoming the limitations of traditional therapies for pathological scars by integrating sustained drug release with minimally invasive transdermal technologies, potentially enhancing treatment efficacy for these challenging skin lesions.

This study found that FDA-approved low-level light/laser therapy devices significantly increased hair density in individuals with pattern hair loss compared to sham devices.

This review highlights the promising biomedical applications of marine-derived polysaccharides, proteins, and peptides, particularly in drug delivery and wound healing. It discusses their potential as biomaterials in creating nanocarriers, hydrogels, and more, alongside fabrication strategies, regulatory challenges, and sustainability considerations.

This case report describes a patient who developed drug-induced lupus erythematosus after treatment with a monoclonal antibody combination against the SARS-CoV-2 surface protein, highlighting the need for careful follow-up.

This expert consensus statement highlights that while targeted cancer therapies significantly improve patient survival, they often result in various skin toxicities, underscoring the need for early diagnosis, management, and multidisciplinary care to maintain patients' quality of life and ensure treatment continuity.

This review explores the recent developments and diverse applications of microneedles in drug delivery and diagnostic platforms but reports no new clinical results.

This study reported that an ATRA-loaded nanostructured lipid carrier gel (ATRA-NLC-Gel) improved symptoms of alopecia areata in mice by enhancing transdermal drug delivery, reducing skin irritation, and promoting hair regrowth through targeted follicle enrichment and pathway activation.

This source concludes that repurposing existing drugs, such as using metformin with other treatments in advanced non-small cell lung cancer, may enhance cancer patient outcomes, although various technical and legal challenges need addressing.

In this study, peginterferon alfa-2b plus ribavirin therapy in hepatitis C patients was associated with serious adverse drug reactions in 20% of cases, highlighting differences from clinical trial findings.

This review evaluates recent advances from 2016 to 2022 in the use of microbubbles and nanobubbles, highlighting their potential for safer diagnostic and therapeutic applications in radiology and medicine without the side effects associated with traditional methods.

This review discusses various adverse skin reactions linked to cardiovascular medications and reports no new clinical results, highlighting the need for vigilance when prescribing these drugs.

This study reviewed the publication trends and key findings on alternative therapies for androgenetic alopecia, highlighting the increasing research interest in dutasteride and nontopical minoxidil, while noting a lack of high-quality trials for nontopical minoxidil formulations.

This study concluded that qianliekang combined with liuweidihuangwan is a more economical treatment for benign prostatic hyperplasia compared to finasteride plus tamsulosin.

This review discusses the potential of using nanomaterial-based drug delivery systems to improve the treatment of polycystic ovary syndrome but reports no new clinical results, highlighting future research directions.

In this study, a self-adaptive nanozyme embedded in a madecassoside-enriched hydrogel demonstrated strong antibacterial efficacy and accelerated healing in wounds infected with drug-resistant bacteria, as evidenced by improved repair and regeneration in MRSA-infected mice and preclinical pig models.

This review identifies FDA-cleared home-use photobiomodulation devices for androgenetic alopecia treatment and highlights their excellent safety profile but notes the lack of long-term comparative studies.

In this study, researchers used computational modeling and virtual screening to identify two FDA-approved drugs, Tadalafil and Finasteride, that may effectively inhibit key proteins involved in melanoma progression, suggesting potential for new therapeutic strategies against aggressive melanoma.

This study found that the ashwagandha extracts ASH-Ext1 and ASH-Ext2 show different pharmacological activities in cell models due to their distinct withanolide proportions, highlighting the need for standardized extraction protocols to ensure consistent therapeutic efficacy.

This study observed that intravenous ferric carboxymaltose did not inhibit the drug-induced reduction of inflammatory activity in patients with inflammatory bowel disease, as indicated by lower CRP levels.

In this study, the researchers identified that perturbing both AKT1 and MDM2 significantly reduces epithelial-mesenchymal transition in melanoma, proposing Cialis and Finasteride as potential therapeutic candidates with favorable properties for managing aggressive melanoma.

This review examines recent advances in androgenetic alopecia treatment, highlighting how multifunctional plant extracts combined with nanotechnology could improve topical therapy efficacy by enhancing local drug bioavailability and targeting, addressing limitations of existing treatments.

This study proposed a new approach to combat leishmaniasis by targeting host proteins rather than the parasite itself, identifying eight existing drugs as potential treatments despite not having been previously tested on leishmaniasis.

This study found that injecting drug users attending an oral substitution therapy center often experience skin lesions, which negatively impact their psychosocial health and quality of life.

This review summarizes recent advances in the development of engineered polypeptide-based drug delivery systems for cancer therapy, highlighting their potential to improve treatment efficacy and reduce side effects.