September 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study applied a new RGB trichrome stain to human skin samples, revealing distinct structural staining in normal tissues and potential proteoglycan-rich zones in hair follicles.
March 2021 in “CRC Press eBooks” This review discusses the importance of physical examinations in trichology, emphasizing their role in diagnosing conditions like alopecia and hair dystrophies, and reports no new clinical results.
162 citations
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August 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” This study introduces a novel non-invasive method called "differential stripping" to quantify the penetration of topically applied substances into hair follicles.
37 citations
,
December 2003 in “Reproductive Toxicology” The researchers reported that the rat Hershberger assay reliably detected endocrine-disrupting effects of finasteride, procymidone, and 17α-methyltestosterone, validating the assay's sensitivity for identifying hormonal activity.
2 citations
,
January 2022 in “Clinical, Cosmetic and Investigational Dermatology” This study found that a refined wash test can effectively differentiate shedding hair characteristics among normal individuals, and patients with androgenetic alopecia or telogen effluvium, aiding in diagnosis and monitoring.
38 citations
,
May 2009 in “European journal of dermatology/EJD. European journal of dermatology” This study found that the TrichoScan method for evaluating hair loss showed excellent correlation with manual marking and provided more consistent, reproducible results with less variability and operator error.
7 citations
,
December 1995 in “The American Journal of Cosmetic Surgery” This study suggests that the O'Connor Tweezer Dexterity Test is a valuable tool for screening surgical assistants in hair transplantation for their ability to accurately and quickly place hair-grafts.
5 citations
,
January 2018 in “Skin Research and Technology” This letter compares automated digital image analysis (TrichoScan) with manual marking of hairs in male patients with androgenetic alopecia but reports no new results.
22 citations
,
July 2010 in “Drug Testing and Analysis” This study presents a rapid method for detecting multiple xenobiotics in urine, effectively identifying 45 compounds banned in sports with detection limits below WADA's performance levels.
1 citations
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May 2018 in “jurnal veteriner” This study concluded that among the three diagnostic techniques for detecting Demodex mites in dogs, the scraping technique provided the best diagnostic value.
7 citations
,
August 2023 in “Therapeutic Innovation & Regulatory Science” This study developed a standardized strategy using blinded expert panel reviews of home videos to assess developmental milestones in infants with neurodegenerative diseases, finding it to be feasible, meaningful, and preferred by parent/caregivers compared to in-clinic assessments.
10 citations
,
June 2018 in “Journal of visualized experiments” This study demonstrated that lactate dehydrogenase activity is notably high in quiescent hair follicle stem cells within mouse skin using a specific enzymatic activity assay.
12 citations
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May 2017 in “Journal of pharmaceutical and biomedical analysis” In this study, researchers developed a method using scalp cyanoacrylate biopsy and advanced imaging techniques to effectively measure and visualize the distribution of anti-dandruff shampoo ingredients zinc pyrithione and climbazole within the scalp follicular infundibulum.
July 2016 in “Journal of Investigative Dermatology” This article introduces an online quiz by the Journal of Investigative Dermatology, connecting its questions to findings from a specific JID article, and it reports no new results.
17 citations
,
August 2015 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” This study concluded that the best approach for detecting Androsta-1,4,6-triene-3,17-dione administration in horses is monitoring the metabolites M1b or M4 in urine, detectable up to 77 hours post-administration.
2 citations
,
April 2018 in “Current Pharmaceutical Analysis” This study developed a new, simple, and economical RP-TLC method with densitometry that is suitable for routine analysis of finasteride in tablet dosage form, meeting analytical validation criteria.
12 citations
,
January 2009 in “Breast Cancer Basic and Clinical Research” This study found that the combination of mammography and hair X-ray diffraction increased sensitivity for detecting breast cancer compared to using each method alone.
9 citations
,
September 2017 in “Journal of Investigative Dermatology Symposium Proceedings” In this study, PGD2 was shown to increase testosterone production in human keratinocytes through reactive oxygen species, suggesting potential benefits of antioxidants like N-acetyl-cysteine for AGA patients.
19 citations
,
November 1971 in “Clinica Chimica Acta” In this study, the researchers found that the absence of the NFI-C transcription factor delayed the hair growth cycle in mice by affecting key gene expressions and signaling pathways.
February 2016 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” A hair test can accurately predict if a person with hair loss will respond to minoxidil treatment.
15 citations
,
October 2010 in “Archives of Toxicology” This study found that the yeast androgen screen (YAS) could detect the activity of methyltestosterone in urine for a longer period than classical GC/MS, potentially identifying long-lasting metabolites.
14 citations
,
May 2013 in “Experimental Dermatology” This study found that the modified wash test was generally more effective than TrichoScan® for diagnosing hair loss, particularly telogen effluvium, though both methods showed only fair concordance with clinical diagnosis.
8 citations
,
June 1981 in “Clinica Chimica Acta”
September 2023 in “Skin appendage disorders” This pilot study detailed the use of Hair-to-Hair-matching technology™ in a clinical trial to assess botulinum toxin's efficacy in treating male androgenetic alopecia, providing a precise method for evaluating hair count and thickness changes over time.
31 citations
,
August 2001 in “PubMed” This study found that the TrichoScan method detected significant increases in hair counts and cumulative hair thickness in men after finasteride treatment, suggesting its potential for monitoring hair treatment responses.
June 2024 in “Frontiers in pharmacology” This study found that a 2-deoxy-D-ribose gel stimulated hair follicle growth in mice with androgenic alopecia, showing effects similar to minoxidil without additional benefits from combining the two treatments.
July 2023 in “Dermatology Practical & Conceptual” This study found that a positive anagen pull test can be an indicator of lichen planopilaris activity, suggesting its utility in the clinical assessment of this condition.
70 citations
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June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” This study reports that the TrichoScan method effectively measures hair growth parameters and detected significant improvements in hair counts and thickness in men with androgenetic alopecia after finasteride treatment.
3 citations
,
February 2015 in “Scientific Research and Essays” This study found that S. rautanenii bark extract has an anti-proliferative effect on D. dorotocephala, suggesting it may have potential anticancer properties when evaluated using inexpensive planaria assays.
11 citations
,
December 2002 in “Controlled Clinical Trials” This study suggests that simple absolute threshold monitoring rules for compliance using the biomarker DHT perform similarly to more complex methods in the Prostate Cancer Prevention Trial.