October 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Mice treatments didn't grow hair, a patient treatment may affect immune response, and people with hair loss often feel anxious or depressed.
May 2017 in “Urology and andrology” Finasteride and dutasteride, used for prostate issues and hair loss, can cause side effects like sexual dysfunction and mental issues, which may continue even after stopping the medication, a condition called post-finasteride syndrome, for which there's currently no cure.
68 citations
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May 2021 in “Endocrine” This review discusses the emerging "endocrine phenotype" of COVID-19, highlighting the implications for managing diabetes, obesity, vitamin D deficiency, and other endocrine conditions in affected patients.
42 citations
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March 2008 in “Molecular and Cellular Endocrinology” This review explores the potential (neuro-)endocrine influences on hair follicle epithelial stem cell biology and emphasizes the need for more systematic research, but it provides no new empirical results.
37 citations
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October 2021 in “Nutrients” This study discusses the potential association between low vitamin D levels and insulin resistance, suggesting that vitamin D deficiency may contribute to disorders like obesity and diabetes, but emphasizes the need for further research to confirm these links.
22 citations
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November 2016 in “International journal of molecular sciences” This study suggests that impaired VDR signaling in mice leads to dysregulated Ddit4 expression, impacting hair cycle progression and wound healing.
1 citations
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January 2010 in “Springer eBooks” Certain micronutrients may improve hair and nail health, but more research is needed to confirm their benefits.
March 2026 in “Nutrients” This study found that adequate vitamin D status is necessary for metformin to effectively reduce prolactin levels in men with iatrogenic hyperprolactinemia, while improvements in glycemic control were observed across all vitamin D groups.
January 2025 in “International Journal of Molecular Sciences” This study showed that vitamin D receptor gene-deficient rats exhibit hair loss and skin abnormalities due to differences in gene and protein expression patterns, while ligand-independent VDR action is crucial for normal hair cycle maintenance and skin formation.
47 citations
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July 2014 in “European Journal of Pharmaceutics and Biopharmaceutics” This study concluded that polymeric nanoparticles effectively targeted hair follicles for drug delivery, but the organogel formulation did not enhance their penetration into the hair shaft.
September 2026 in “World Journal of Pharmacy and Pharmaceutical Sciences” This study reports the successful formulation of a stable herbal hair serum with Catharanthus roseus extract and other ingredients, noting it has a suitable pH, consistency, and stability, suggesting potential effectiveness as a natural alternative for hair care pending further clinical trials.
March 2025 in “Molecules” This study explored the in vitro skin penetration of two compounds from Tectona grandis leaf extract used for standardization and found that compound 1 penetrates more efficiently than compound 2, especially with a propylene glycol enhancer.
August 2023 in “Health Sciences and Pharmacy Journal” In this review, researchers identified 10 natural plants, including candlenut and clove, that have shown potential to inhibit alopecia progression and stimulate hair growth due to their diverse phytochemical and pharmacological properties in vitro and in vivo.
31 citations
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September 2020 in “Stem Cell Research & Therapy” Hair follicle stem cells may help repair the brain after a stroke.
13 citations
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April 2021 in “International Journal of Molecular Sciences” This study found that the fermented black soybean product GR-SC65 reduced particulate matter-induced cell death and oxidative stress in A549 cells, suggesting potential as a therapeutic agent for lung injury prevention.
50 citations
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March 2001 in “Clinics in dermatology” This paper reviews the complex anatomy and development of human hair and emphasizes the need to understand these processes for interpreting drug incorporation into hair, with no new clinical results reported.
May 2026 in “Inovasi Kesehatan Global” This case report describes a 7-year-old boy with Tinea favosa caused by Trichophyton schoenleinii, treated for 8–12 weeks with oral griseofulvin and ketoconazole cream, leading to recovery from crusts and inflammation but permanent hair loss in some areas.
November 2025 in “Zenodo (CERN European Organization for Nuclear Research)” This study reports that a formulated herbal hair serum containing ingredients like Nigella Savita, ginger, and vitamin E shows significant potential for promoting hair growth, reducing hair fall, and improving manageability, suggesting its promise as a natural hair care product pending further clinical evaluation.
This review reports that exosome-based therapies, coupled with nanotechnology and AI, show promise in aesthetic medicine, notably in skin rejuvenation and hair restoration, but large-scale trials and clearer regulatory frameworks are needed for effective clinical adoption.
12 citations
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December 1962 in “Journal of Investigative Dermatology” April 2016 in “Pharmaciana” This study found that a combination of liquorice and aloe vera extracts, particularly combination 1, resulted in the most optimal hair growth in rabbits over a 28-day period.
16 citations
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August 2019 in “Journal of the Chinese Medical Association” This study reported that adipose-derived stem cells may promote burn wound healing and skin appendage regeneration in a rat model, suggesting a potential approach for improving burn treatments.
January 2025 in “International Journal of Research and Innovation in Applied Science” This study aimed to enhance the skin penetration of minoxidil by encapsulating it in glycerosomal vesicles, offering a potential improvement in transdermal drug delivery for treating androgenetic alopecia. Results of the investigation were not reported.
January 2021 in “Our Dermatology Online” This case report discusses alopecia syphilitica in a young Belgian man, notes that hair loss was his only symptom, and highlights the improvement following penicillin treatment.
2 citations
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June 2016 in “Journal of Medical Science And clinical Research” This study examines the potential effectiveness of Barever natural hair inhibitor, which includes papaya and other herbal ingredients, in reducing hair growth permanently when applied after hair removal.
This study evaluated various herbal blends of powdered leaves, including Henna and Indigo, for their coloring and sensitivity reactions, finding Henna and Indigo to be effective natural colorants for achieving a reddish-brown hair color with better retention than marketed herbal hair dyes.
September 1961 in “Archives of Dermatology” This letter contains an apology from the author to Dr. Malkinson for remarks that were unintentionally offensive, acknowledging Dr. Malkinson's superior understanding of the discussed problem.
February 2025 in “Processes” This study highlights the potential of chitosan nanoparticles to improve cannabidiol solubility and delivery for treating alopecia, suggesting a promising approach for transdermal delivery of hydrophobic compounds.
8 citations
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March 1979 in “International Journal of Dermatology” Dr. Vera H. Price's 1979 work emphasizes the importance of accurate diagnosis and personalized treatment for hair loss.
3 citations
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May 1999 in “Dermatologic Surgery” Dr. Connelly agrees that linear basal cell carcinomas might be more aggressive but highlights the study's lack of clear criteria to identify them.