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Minoxidil given intravenously caused small changes in diastolic blood pressure and increased heart rate at higher concentrations in patients with high blood pressure.

Cyclosporine is effective for skin conditions but has declined in use due to toxicity concerns.

Chemotherapy in the first trimester of pregnancy is risky, but in the second and third trimesters, it's generally safe with careful drug selection and timing.

Pill organizers and cutters can help with taking medication regularly but may affect the medication's effectiveness and safety.

Using low-dose IL-2 to increase regulatory T cells might be a safe way to treat type 1 diabetes without severe side effects.

Low-dose oral isotretinoin improved hair loss and facial bumps in patients with a specific type of hair loss.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Topical corticosteroid foams are effective, safe, and easy to use for treating various skin conditions.

People often struggle to consistently use contraceptives and other medications, and long-acting options might be better for those who want to avoid daily doses.

Some common medications can harm male fertility, but many effects can be reversed.

Oclacitinib effectively treated a skin condition in dogs that didn't respond to other immunosuppressants.

The drug combination was safe and showed promise in treating advanced tumors.

The document concludes that PK/PD modeling is important for determining the safe and effective dosages of drugs.

New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.

The Brazilian Society of Dermatology agrees that oral isotretinoin is effective for acne and other skin conditions, and it's safe when monitored, but more research is needed on dosing and duration.

Some acne medications have side effects; doctors should educate patients and may not need to do frequent lab tests for all.

Scalp cooling is largely ineffective in preventing hair loss from breast cancer chemotherapy.

Combining methotrexate with low-dose prednisone is more effective for hair regrowth in alopecia areata totalis.

Scale created to measure hair loss in men and women; MK-386 reduces acne; Niaspan treats dyslipidemia; minoxidil increases heart rate.

More research is needed on the health effects of hormone therapy for transgender and nonbinary people.

Sorafenib helps some advanced cancers alone or with other treatments, but not all, and research continues to improve its use.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

Trastuzumab deruxtecan is effective for HER2-positive breast cancer but requires careful management of side effects.

Certain hormone treatments can improve acne and related conditions in women.

Temozolomide improves survival in grade III glioma patients without harming quality of life.

Acitretin is effective for severe psoriasis and can be used long-term due to no immunosuppression, but must be carefully monitored for side effects and is not for pregnant women.

Minoxidil effectively treats severe hypertension but may cause side effects, so careful monitoring is needed.

Carboplatin-paclitaxel is preferred for advanced lung cancer due to its balance of affordability and patient well-being.

No treatment has been proven to effectively stop hair loss or regrow hair in Frontal Fibrosing Alopecia, and more research is needed.

Scalp cooling therapy helps preserve hair during chemotherapy for most patients.