July 2019 in “Indian dermatology online journal” This case report highlights an unusual trichoscopic appearance in alopecia areata due to dithranol staining, which may obscure typical patterns and reveal atypical vascular features in the interfollicular spaces.
3 citations
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October 1990 in “Journal of the American Academy of Dermatology” This case report describes a patient with lichen nitidus whose lesions improved following treatment with oral astemizole and topical steroids, although spontaneous resolution remains a possibility.
December 2020 in “Rev. Amazon.” This study identified that 80% of a rural population in Ecuador uses medicinal plants like Aloe vera for treating hair conditions, highlighting the prevalence of ancestral plant knowledge.
This review discusses the use of medicinal plants for combating and preventing alopecia but reports no clinical results, emphasizing the presence of plant-based cosmetics on the market.
6 citations
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July 2023 in “Plants” This study found that Datura metel extracts obtained through supercritical CO2 extraction demonstrated significant biological activity, including antioxidant and anti-inflammatory properties, and effectively promoted wound closure and collagen preservation, comparable to standard treatments, in laboratory experiments.
August 2025 in “OPAL (Open@LaTrobe) (La Trobe University)” In this study, PA-011 extract was reported to promote hair growth and alleviate alopecia areata symptoms in mice by reducing skin inflammation and modulating skin microbiota.
2 citations
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December 2014 in “Research & Reviews: Journal of Pharmacy and Pharmaceutical Sciences” This study found that a pet ether extract of Daucus carota promoted hair growth by inducing and prolonging the anagen phase in albino rats, surpassing the effects of 1% minoxidil.
1 citations
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January 2019 in “Zenodo (CERN European Organization for Nuclear Research)” This anatomical study on Eclipta alba concluded that unique secretory structures in stems and leaves may serve as identifying features of the plant and the Asteraceae family.
12 citations
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June 2017 in “Dermatologic therapy” This study reported that dithranol treatment up to 3% concentration led to hair regrowth in alopecia areata patients who had previously failed ultra-potent steroids, with regrowth observed across all severity levels.
2 citations
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October 2020 in “Journal of Investigative Dermatology Symposium Proceedings” This study reports promising preliminary trends in the safety and efficacy of a botanical drug candidate for pediatric alopecia areata, but conclusive results are not yet available.
This study concluded that the antioxidant and hair growth activity of Trigonella plants were higher compared to Geranium wallichianum, with a potential correlation between antioxidant activity and hair growth in albino rats.
March 2026 in “Israel Journal of Plant Sciences” This study investigated the endophytic bacterial community of Eclipta prostrata, finding that these microorganisms contribute to the plant’s stress tolerance and detoxification, which may enhance its medicinal properties by supporting the synthesis and stability of beneficial metabolites.
7 citations
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January 2012 in “International Journal of Trichology” A man with Woolly Hair Syndrome had very curly, fragile hair, and doctors used a special scalp examination to diagnose him without invasive tests.
3 citations
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December 2019 in “International Journal of Pharmacology” This study found that Poria cocos extract may enhance human follicle dermal papilla cell proliferation through the AKT signaling pathway, indicating its potential for hair growth promotion.
65 citations
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April 2021 in “Natural Products and Bioprospecting” This review discusses the traditional uses and pharmacologically active compounds of 22 Dendrobium species for dermatological disorders but reports no new results, highlighting the need for further research.
August 2024 in “Bioorganic Chemistry” This study found that oral administration of cedrol, a component of ginger, improved hair regeneration and reduced hair follicle damage in cyclophosphamide-induced alopecia areata in mice more effectively than external administration, by enhancing cytokine expression and modulating key signaling pathways.
January 2022 in “Pharmaceutical Sciences Asia” This study found that alcoholic extracts from Clitoria ternatea flowers increased the proliferation of human dermal papilla cells and stimulated initial hair growth in mice, with effects similar to minoxidil.
1 citations
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June 2018 in “International Journal of Dermatology” DNCB is highly effective for treating alopecia areata with minimal long-term side effects.
2 citations
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January 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that low temperatures and nitrogen deficiency trigger root hair elongation through a molecular mechanism involving the receptor kinase FERONIA and the TOR Complex 1.
82 citations
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January 2011 in “New Phytologist” This study demonstrated that AtVLN4 plays a role in root hair growth by regulating actin organization in a calcium-dependent manner.
3 citations
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January 2023 in “Journal of Biomedical and Allied Research” This review examines the therapeutic applications and potential pharmacological properties of Calotropis gigantea but presents no new clinical findings.
June 2010 in “Journal of Medicine and Life Science” This study suggests that Orostachys iwarenge extract may promote hair growth by increasing the proliferation of dermal papilla cells in an in-vitro setting.
22 citations
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January 2021 in “Pharmacognosy Journal” This review discusses the traditional uses, phytochemical, and pharmacological studies on Ageratum conyzoides, Tridax procumbens, and Bidens pilosa, emphasizing the need for further clinical research into their medicinal potential, but it does not report new results.
18 citations
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October 2002 in “Veterinary dermatology” This study observed that follicular dysplasia in Weimar Pointers produces histopathological features and hair abnormalities similar to color dilution alopecia, though less severe.
May 2025 in “Scientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal Biology” In this study, researchers developed "Akaro Spectra," an antiparasitic tablet for dogs using cryodestruction of plant materials, which showed 100% efficacy against Otodectes cynotis ticks by the second day and 93.76% efficacy against Ixodes, Dermacentor, and Rhipicephalus ticks.
March 2014 in “한국유기농업학회지” In this study, Hypochoeris radicata L. showed increased growth and colony formation when cut, and its extracts inhibited seed germination and growth in other plants while demonstrating varying antifungal activity.
6 citations
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March 2014 in “Herba Polonica” This article reviews treatment options for androgenetic alopecia, highlighting potential uses of plant materials, but reports no new clinical results.
44 citations
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January 2023 in “New Phytologist” This study found that low temperature triggers root hair elongation in Arabidopsis thaliana through a FERONIA-ROP2-TORC signaling pathway, also activated by nitrogen deficiency.
July 2026 in “International Journal of Research in Pharmacology & Pharmacotherapeutics” In this study, the methanolic extract of Tridax procumbens Linn demonstrated significant antiulcer activity in a mice model of acetic acid-induced ulcerative colitis, offering 57.12% ulcer protection compared to 50.60% by the standard drug prednisolone.
11 citations
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October 2021 in “Journal of Herbmed Pharmacology” This review examines the therapeutic benefits, chemical composition, and medicinal uses of Delphinium species, along with their toxic effects; it reports no new clinical results.