research Loss of Epidermal Melanin Unit Integrity in Human Skin During Melanoma Genesis
Melanoma development can be linked to the breakdown of skin's melanin-producing units.
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research Human Pilosebaceous Culture
Hair follicle cells can help heal wounds and study skin diseases.
research Cryptomphalus Aspersa Mollusc Egg Extract Promotes Regenerative Effects in Human Dermal Papilla Stem Cells
Mollusc egg extract helps skin and hair cells grow and heal.
research Bioengineering a 3D Integumentary Organ System from iPS Cells Using an In Vivo Transplantation Model
Researchers created a fully functional, bioengineered skin system with hair from stem cells that successfully integrated when transplanted into mice.
research Stem Cell Apoptosis in HIV-1 Alopecia
HIV-1 may cause increased stem cell death in hair follicles, leading to hair loss.
research Physiological Doses of Red Light Induce IL-4 Release in Cocultures Between Human Keratinocytes and Immune Cells
Red light at 627 nm can safely trigger IL-4 release in skin cells, potentially helping treat inflammatory skin conditions.
research Regenerative Medicine Approaches for Engineering a Human Hair Follicle
New treatments for hair loss show promise, including plasma, stem cells, and hair-stimulating complexes, but more research is needed to fully understand them.
research Defects in Mitochondrial DNA Replication and Oxidative Damage in Muscle of mtDNA Mutator Mice
Defective mitochondrial DNA replication causes aging symptoms and increased oxidative damage in mice.
research Zinc, Copper, and Iron in Selected Skin Diseases
Zinc, copper, and iron are important for skin health and may help diagnose skin diseases.
research Pioneer Factors Govern Super-Enhancer Dynamics in Stem Cell Plasticity and Lineage Choice
Super-enhancers controlled by pioneer factors like SOX9 are crucial for stem cell adaptability and identity.
research Bioengineering Skin Constructs
Future research should focus on making bioengineered skin that completely restores all skin functions.
research Disrupted Pancreatic Exocrine Differentiation and Malabsorption in Response to Chronic Elevated Systemic Glucocorticoid
High glucocorticoids cause pancreatic malfunction and malabsorption, reversible with enzyme supplements.
research In Human Skin, UVB Initiates Early Induction of IL-10 Over IL-12 Preferentially in the Expanding Dermal Monocytic/Macrophagic Population
UVB exposure in human skin causes macrophages to produce more IL-10 and less IL-12, leading to immunosuppression.
research Revolutionizing Radiotoxicity Management with Mesenchymal Stem Cells and Their Derivatives: A Focus on Radiation-Induced Cystitis
Mesenchymal stem cells could help treat radiation-induced bladder damage but more research is needed to overcome current limitations.
research Human Skin Stem Cells and the Aging Process
Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.
research Multimodal Imaging of Hair Follicle Bulge-Derived Stem Cells in a Mouse Model of Traumatic Brain Injury
Hair follicle stem cells might help treat traumatic brain injury.
research Transepidermal UV Radiation of Scalp Skin Ex Vivo Induces Hair Follicle Damage That Is Alleviated by Topical Treatment with Caffeine
Caffeine applied to the scalp can protect hair follicles from UV damage.
research Concise Review: The Plasticity of Stem Cell Niches: A General Property Behind Tissue Homeostasis and Repair
Stem cell niches are adaptable and key for tissue maintenance and repair.
research Age-Induced Hair Greying: The Multiple Effects of Oxidative Stress
Hair greying is caused by oxidative stress damaging hair follicles and melanocytes.
research Role of Cytotoxic T Cells in Chronic Alopecia Areata
Cytotoxic T cells cause hair loss in chronic alopecia areata.
research Transforming Growth Factor-Beta in Stem Cells and Tissue Homeostasis
TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
research TGF-β Family Signaling in Stem Cells
TGF-β signaling is crucial for stem cell maintenance, differentiation, and has implications for cancer treatment.
research Expansion Culture of Hair Follicle Stem Cells Through Uniform Aggregation in Microwell Array Devices
The new microwell device helps grow more hair stem cells that can regenerate hair.
research A Family Business: Stem Cell Progeny Join the Niche to Regulate Homeostasis
Stem cell offspring help control their parent stem cells, affecting tissue health, healing, and cancer.
research Chemotherapy-Induced Alopecia
Chemotherapy often causes hair loss, which usually grows back within 3 to 6 months, but there's no effective treatment to prevent it.
research Air Pollution and Skin Diseases: Adverse Effects of Airborne Particulate Matter on Various Skin Conditions
Air pollution worsens skin diseases and aging by causing inflammation and oxidative stress.
research Regenerative Medicine of Epidermal Structures
New treatments for skin and hair repair show promise, but further improvements are needed.
research Epidermal Stem Cells Manipulated by pDNA-VEGF165/CYD-PEI Nanoparticles Loaded Gelatin/β-TCP Matrix as a Therapeutic Agent and Gene Delivery Vehicle for Wound Healing
The gelatin/β-TCP scaffold with nanoparticles improves wound healing and skin regeneration.
research Coordinated Activation of Wnt in Epithelial and Melanocyte Stem Cells Initiates Pigmented Hair Regeneration
Wnt signaling is crucial for pigmented hair regeneration by controlling stem cell activation and differentiation.
research Shushing Down the Epigenetic Landscape Towards Stem Cell Differentiation
The document concludes that pig iPSCs show promise for transplant therapies and the field is advancing in controlling cell behavior for biology and medicine.