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    Glossary Disease Activity

    Disease activity refers to the current state and severity of a disease, particularly in the context of autoimmune conditions that can affect hair loss, such as alopecia areata. It is relevant to hair loss as it helps in assessing the progression or regression of the condition, guiding treatment decisions. Key distinguishing characteristics of disease activity include the presence of new hair loss patches, changes in existing patches, and the overall inflammatory response in the scalp. Monitoring disease activity is crucial for understanding the potential for hair regrowth and the effectiveness of therapeutic interventions.

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    1. Serial trichoscopy vs. modified hair pull test for monitoring the disease activity and treatment response of localized alopecia areata Journal of the European Academy of Dermatology and Venereology · 2016 · 11 citations
    2. Prevalence of depression and anxiety and their association with disease activity in patients with systemic lupus erythematosus: A cross-sectional study Saudi Journal of Internal Medicine · 2026
    3. 51826 PRO-C22 - A Novel Serological Biomarker of Tissue Damage is Associated with Disease Severity, Disease Activity, and Systemic Inflammation in Patients with Hidradenitis Suppurativa Journal of the American Academy of Dermatology · 2024
    4. FRI0310 Achievement of low disease activity in lupus patients treated with belimumab is independent of serologic status at baseline: a real-life observational study 2018
    5. Low disease activity—irrespective of serologic status at baseline—associated with reduction of corticosteroid dose and number of flares in patients with systemic lupus erythematosus treated with belimumab: A real-life observational study Seminars in Arthritis and Rheumatism · 2018 · 70 citations
    6. Can the Second to Fourth Digit Ratio (2D : 4D) Be a Marker to Determine Ankylosing Spondylitis Disease Activity? Disease Markers · 2019 · 3 citations
    7. Reducing Disease Activity in Systemic Lupus Erythematosus through Adjunctive Naturopathy and Yoga: A Six-Month Case Report with Serial Immunological, Haematological, and Patient-Reported Outcome Monitoring International Journal of Research and Innovation in Applied Science · 2026
    8. Serum Granulysin Levels in Vitiligo and Alopecia Areata: A Potential Biomarker for Disease Activity and Dermoscopic Evaluation Journal of Clinical Medicine · 2025
    9. GPX4 mRNA levels in the PMNs are negatively correlated with autoantibody production, disease activity and lupus alopecia in SLE Research Square (Research Square) · 2023
    10. 570 Examining cutaneous disease activity as an outcome measure for clinical trials in dermatomyositis Journal of Investigative Dermatology · 2018
    11. 129 Utilizing Polygenic score in predicting the disease activity and arthritis in psoriasis patients Journal of Investigative Dermatology · 2024
    12. Biomarkers of alopecia areata disease activity and response to corticosteroid treatment Experimental dermatology · 2015 · 65 citations
    13. Evaluation of disease activity and damage in different subtypes of cutaneous lupus erythematosus using the CLASI Journal of the European Academy of Dermatology and Venereology · 2010 · 19 citations
    14. LP-159 Studying the disease activity and the degree of internal organ damage in systemic lupus erythematosus patients in the Kazakh population 2023
    15. Finasteride inhibits the disease-modifying activity of progesterone in the hippocampus kindling model of epileptogenesis Epilepsy & Behavior · 2012 · 26 citations
    16. Biological Activities of 2,3,5,4′-Tetrahydroxystilbene-2-O-<i>β</i>-D-Glucoside in Antiaging and Antiaging-Related Disease Treatments Oxidative medicine and cellular longevity · 2016 · 43 citations
    17. Measures of Adult Systemic Lupus Erythematosus: Disease Activity and Damage Arthritis Care & Research · 2020 · 44 citations
    18. Alopecia areata: trichoscopic markers in determining disease activity Journal of the Egyptian Womenʼs Dermatologic Society · 2023 · 2 citations
    19. All Subcomponents of the Cutaneous Lupus Erythematosus Disease Area and Severity Index–Activity (CLASI-A) are Relevant to Identify and Detect Changes in Skin Activity SKIN The Journal of Cutaneous Medicine · 2026
    20. Stem cell activity shapes the pleiotropic effects of IFN-γ and TGF-β in autoimmune diseases, infections, and cancer, and drives autoimmune flares and remissions Frontiers in Immunology · 2025
    21. Faculty Opinions recommendation of Finasteride inhibits the disease-modifying activity of progesterone in the hippocampus kindling model of epileptogenesis. Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2015
    22. Rosmarinus officinalis and Skin: Antioxidant Activity and Possible Therapeutical Role in Cutaneous Diseases Antioxidants · 2023 · 7 citations
    23. Trichoscopic findings in alopecia areata and their relation to disease activity, severity and clinical subtype in Turkish patients Australasian Journal of Dermatology · 2013 · 26 citations
    24. Serum IFNα as a Biomarker for Cutaneous Lupus: Insights into Disease Activity, Severity, Therapeutic Monitoring and Clinical Trial Application Journal of Investigative Dermatology · 2025
    25. SARS‐COV2 Vaccination and Hidradenitis Suppurativa: Role of Vaccination in Disease Activity JEADV Clinical Practice · 2024
    26. Anifrolumab treatment improves patient-reported quality of life and decreases disease activity and corticosteroid use in patients with systemic lupus erythematosus: A qualitative study in Denmark Lupus · 2024
    27. Topical Mechlorethamine Restores Autoimmune-Arrested Follicular Activity in Mice with an Alopecia Areata-Like Disease by Targeting Infiltrated Lymphocytes Journal of Investigative Dermatology · 2003 · 19 citations
    28. P730 High-dosed intravenous iron replacement therapy does not hinder drug-induced amelioration of disease activity in IBD patients with iron deficiency anaemia Journal of Crohn s and Colitis · 2018
    29. Understanding the role of prostaglandin E2 in regulating human platelet activity in health and disease Thrombosis Research · 2015 · 35 citations
    30. Polycystic ovary syndrome: the impact of diet and physical activity on the course of the disease Quality in Sport · 2024