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Cholesterol sulfate buildup due to a genetic mutation disrupts the skin barrier, leading to the scaling skin seen in X-linked ichthyosis.

Pregnancy can increase lupus activity, but careful planning and treatment can improve outcomes.

Hair mineral analysis might help diagnose diseases early, but standard methods are needed.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

Animal models have helped understand hair loss from alopecia areata and find new treatments.

Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Oral tofacitinib can significantly improve recalcitrant lichen planopilaris.

Human skin cells produce proenkephalin, which changes with environmental factors and skin diseases.

Aromatase gene variation may increase female hair loss risk.

Androgenetic alopecia involves genetics, hormones, and can be treated with medications or surgery.

Some African American women's central scalp hair loss is linked to genetics and past fungal scalp infections, with more research needed on other causes.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Taking low-dose spironolactone and metformin together works better for PCOS symptoms than either drug alone.

Finasteride, CPA, and flutamide are all equally effective in reducing excessive hair growth in women.

The document concludes that skin biopsies, genetic and environmental factors, and specific treatments are important in managing cutaneous lupus erythematosus.

Human hair follicle stem cells can turn into multiple cell types but lose some of this ability after being grown in the lab for a long time.

Polycystic ovarian shape is a genetic sign of PCOS and its hormonal and metabolic features can be inherited.

Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.

Prostate cancer prevention includes diet changes, supplements, and medications, with more answers expected soon.

Keratin proteins are crucial for healthy skin, but mutations can cause skin disorders with no effective treatments yet.

Certain groups may need vitamin supplements to improve hair health and prevent other health problems.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.

Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.

The document concludes that alopecia areata is an autoimmune disease without a definitive cure, but treatments like corticosteroids are commonly used.

Skin problems are very common in people with end-stage kidney disease.

Prolactin affects the production of different keratins in human hair, which could lead to new treatments for skin and hair disorders.

Some birth control pills have a higher risk of blood clots than others.

The 308-nm excimer laser is a promising treatment for vitiligo with varying success and mild side effects.