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Cyclosporin extends hair growth in mice, but high-dose corticosteroids block this effect.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Most hirsutism cases are due to PCOS, and treatment focuses on lowering testosterone and blocking its effects.

The document concludes that various cosmetic and drug treatments are available for hirsutism, and some new drugs show promise.

Finasteride treats enlarged prostate and may help with baldness, but effects on sexual function and male fetuses are unclear.

Prostate cells have proteins that bind to specific hormones, which can increase protein production when activated by these hormones.

Steroidogenesis inhibitors change but don't stop androgen production in prostate cancer.

Testosterone and some of its forms can strongly stimulate oil gland growth in skin.

The availability of certain hormones and specific stimulation patterns affect long-term synaptic changes in the male rat brain.

Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.

Finasteride effectively treats baldness but may cause sexual side effects.

18β-glycyrrhetinic acid from licorice root is good for skin and hair treatments but has absorption challenges.

Dutasteride and finasteride do not significantly affect bone density, blood fats, or blood production, but slightly lower PSA levels and minimally impact sexual function in healthy young men.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

ADT, especially enzalutamide, may increase the risk of heart rhythm problems and sudden death in men.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.

Ketoconazole reduced hair growth and improved acne in women, but caused side effects needing careful monitoring.

Hair follicle regeneration possible, more research needed.

Androgen self-administration might be controlled by membrane receptors, not nuclear ones.

The conclusion is that small hair follicles cause baldness in macaques, and treatments like antiandrogens and minoxidil can prevent hair loss and promote regrowth.

Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.

Male hormones worsen kidney transplant damage, but blocking them helps.

Androgenic steroids can slow down or stop the growth of certain skin fungi.

Breast cancer treatments work better with AR activation, improving results and reducing side effects.

Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.

Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.

The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.

Finasteride doesn't harm bone density in older men with BPH.

Plant-based compounds might be a promising alternative for prostate cancer treatment with fewer side effects.