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A cystic fibrosis patient developed Cushing's syndrome from a drug interaction between itraconazole and budesonide, which improved after stopping the medications.

A cystic fibrosis patient developed Cushing's syndrome from a drug interaction between itraconazole and inhaled budesonide.

The decision tree can predict drug absorption issues with good accuracy but needs more validation and adjustments for other factors.

CDK4/6 inhibitors have improved treatment outcomes for certain advanced breast cancer patients.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Ketoconazole increases finasteride's effectiveness and lifespan in the body.

Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.

Taking Dutasteride with Ketoconazole can increase Dutasteride's effects and side effects.

Vitamin D is important for bones, hair, blood pressure, and breast development.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Modulating Cytochrome P450 activity could help develop new skin disease treatments.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

Certain genetic variations are linked to higher liver enzyme levels in patients treated for chronic hepatitis C with specific drugs.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Melatonin affects many body functions beyond sleep by interacting with specific receptors in various tissues.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Early diagnosis and individualized treatment improve outcomes for Congenital Adrenal Hyperplasia.

Lignans and neolignans from plants may help protect against various health issues, including cancer and heart disease.

The circadian clock is crucial for tissue renewal and regeneration, affecting stem cell functions and having implications for health and disease.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

Cannabinoids may help treat chronic and chemotherapy-induced neuropathic pain, but more research is needed to confirm their effectiveness and safety.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Dutasteride effectively treats enlarged prostate, reduces prostate cancer risk, and promotes hair regrowth with few side effects.

Hairless protein can both repress and activate vitamin D receptor functions, affecting gene regulation.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

Polygonum multiflorum extract helps hair grow longer and fights the effects of hormones that cause hair loss.