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A cystic fibrosis patient developed Cushing's syndrome from a drug interaction between itraconazole and budesonide, which improved after stopping the medications.

A cystic fibrosis patient developed Cushing's syndrome from a drug interaction between itraconazole and inhaled budesonide.

The decision tree can predict drug absorption issues with good accuracy but needs more validation and adjustments for other factors.

CDK4/6 inhibitors have improved treatment outcomes for certain advanced breast cancer patients.

Taking Dutasteride with Ketoconazole can increase Dutasteride's effects and side effects.

Vitamin D is important for bones, hair, blood pressure, and breast development.

Eicosanoids are crucial for skin health, and targeting their pathways may help treat skin conditions.

Tacrolimus causes fewer acute rejections than cyclosporin A in kidney transplants but doesn't necessarily improve kidney function after one year; cardiovascular risks and side effects vary between the two drugs.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

Ketoconazole increases finasteride's effectiveness and lifespan in the body.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Modulating Cytochrome P450 activity could help develop new skin disease treatments.

DHEA affects multiple receptors and may help with metabolic issues, but its safety and effectiveness in humans are unclear.

Certain genetic variations are linked to higher liver enzyme levels in patients treated for chronic hepatitis C with specific drugs.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

Various treatments exist for hair loss, but more research is needed for better options.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

Non-biologic immunosuppressive drugs are crucial for treating autoimmune and chronic inflammatory skin diseases.

Terbinafine is more effective than itraconazole for toenail fungus, especially in older patients, and debridement improves its effectiveness.

Using three different drugs together may better treat eye diseases like glaucoma and macular degeneration.

Melatonin, a hormone, can help protect skin from aging by reducing stress, inflammation, and damage, and may also help treat hair loss in women.

Polygonum multiflorum extract helps hair grow longer and fights the effects of hormones that cause hair loss.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Dutasteride is effective for treating prostate enlargement and reducing related surgery risk, but is not approved for preventing prostate cancer.