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research The Pathological Dynamics of Androgenetic Alopecia and Its Treatment
Topical spironolactone effectively treats hair loss in women.
research Cross-Interactions of BMP and WNT Signaling Pathways Attenuate Androgen Effect on Hair Follicle Stem Cell Differentiation
BMPs are important for hair growth and can counteract the negative effects of androgens on hair follicle stem cells.
research Telogen Effluvium: Understanding the Hair Follicle Cycle and Hair Loss
Telogen effluvium is hair loss caused by disruption of the normal hair cycle.
research Do Hair Bulb Melanocytes Undergo Apoptosis During Hair Follicle Regression (Catagen)?
Hair follicle melanocytes die during hair regression.
research Cyclosporin A Suppresses TGF-Beta2 Expression Via Calcineurin/NFAT Pathway in Human Dermal Papilla Cells
Cyclosporin A, a drug, reduces TGF-β2 expression in skin cells, potentially causing excessive hair growth through a process involving the calcineurin/NFAT pathway.
research Is Intrafollicular Autophagy an Essential Mechanism That Permits Human Hair Follicles to Remain in Prolonged Anagen In Vivo?
Autophagy, a cell recycling process, is crucial for prolonged hair growth and could be a potential target for treating hair growth disorders.
research Epidermal Growth Factor as a Biological Switch in Hair Growth Cycle
EGF controls hair growth by regulating hair follicles' growth phases.
research Growth Hormone Operates as a Neuroendocrine Regulator of Human Hair Growth Ex Vivo
Growth hormone is important for regulating human hair growth.
research Temporal Layering of Signaling Effectors Drives Chromatin Remodeling During Hair Follicle Stem Cell Lineage Progression
Different signals work together to change gene activity and guide hair follicle stem cells to become specific cell types.
research Clock Genes, Hair Growth, and Aging
Circadian clock genes are important for hair growth and may affect aging-related hair loss and graying.
research Restoration of Spermatogenesis and Male Fertility Using an Androgen Receptor Transgene
Scientists restored fertility in male mice lacking a key fertility gene by using a modified gene.
research Ex Vivo Organ Culture of Human Hair Follicles: A Model Epithelial–Neuroectodermal–Mesenchymal Interaction System
Hair follicle culture helps study cell interactions and effects of substances on tissue growth.
research Identification of Bulge Stem Cells in Mouse and Human Hair Follicles
Scientists found markers called CD34 and CD200 that help identify stem cells in mouse and human hair follicles.
research Molecular Mechanisms Regulating Hair Follicle Development
Understanding hair follicle development can help treat hair loss, skin regeneration, and certain skin cancers.
research The Use of Keratin Biomaterials Derived from Human Hair for the Promotion of Rapid Regeneration of Peripheral Nerves
Keratin from human hair helps nerves heal faster.
research An Extended Epidermal Response Heals Cutaneous Wounds in the Absence of a Hair Follicle Stem Cell Contribution
Skin can heal wounds without hair follicle stem cells, but it takes a bit longer.
research A Meeting of Two Chronobiological Systems: Circadian Proteins Period1 and BMAL1 Modulate the Human Hair Cycle Clock
BMAL1 and Period1 genes can influence human hair growth.
research Gene Expression Profiling Gets to the Root of Human Hair Follicle Stem Cells
Human hair follicle stem cells can be isolated using specific markers for potential therapeutic use.
research Neural Potential of a Stem Cell Population in the Hair Follicle
Stem cells in hair follicles can become various cell types, including neurons.
research Androgen Insufficiency in Women: Diagnostic and Therapeutic Implications
Testosterone replacement can help women with low libido and mood, but they need to have enough estrogen first to avoid side effects.
research Treatment of Hirsutism and Acne in Hyperandrogenism
Medicines that lower androgen levels and hair removal treatments help manage excessive hair and acne in women with PCOS.
research Contrasting Localization of c-Myc with Other Myc Superfamily Transcription Factors in the Human Hair Follicle and During the Hair Growth Cycle
Different Myc family proteins are located in various parts of the hair follicle and may affect stem cell behavior.
research Gsdma3 Is Required for Hair Follicle Differentiation in Mice
The Gsdma3 gene is essential for normal hair development in mice.
research Wanted, Dead and Alive: Why a Multidisciplinary Approach Is Needed to Unlock Hair Treatment Potential
Different fields of expertise must work together to better understand hair growth and create effective hair loss treatments.
research Telogen Effluvium: Causes, Diagnosis, and Treatments
Telogen Effluvium is a condition causing excessive hair loss due to stress, illness, drugs, or hormonal changes, and can be treated with specific products or naturally resolves after 3-4 years.
research Skin Transcriptome Reveals the Periodic Changes in Genes Underlying Cashmere Follicle Transition in Cashmere Goats
The study identified key genes that regulate the growth cycle of cashmere in goats, which could help improve breeding strategies.
research Establishment of Type II 5α-Reductase Over-Expressing Cell Line as an Inhibitor Screening Model
A reliable model for screening type II 5α-reductase inhibitors was created and validated.
research Time-Course RNA-Seq Analysis Reveals Stage-Specific and Melatonin-Triggered Gene Expression Patterns During the Hair Follicle Growth Cycle in Capra Hircus
Melatonin affects gene expression in goat hair follicles, potentially increasing cashmere production.
research Suppression of FGF5 and FGF18 Expression by Cholesterol-Modified siRNAs Promotes Hair Growth in Mice
Cholesterol-modified siRNAs targeting certain genes increased hair growth in mice.