research Development of an Ex Vivo Human Skin Explant Model to Examine Candidate Gene Functions in the Hair Follicle and Epidermis
The model can effectively test gene functions and drug responses in human skin.
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research A First-In-Human Study of BLZ-100 (Tozuleristide) Demonstrates Tolerability and Fluorescence Contrast in Skin Cancer
BLZ-100 is safe for use in skin cancer surgery and may help identify cancerous tissue.
research High Amphiregulin Expression Is a High-Risk Feature of Acute Graft-Versus-Host Disease of the Skin
High amphiregulin in the skin is a bad sign for acute graft-versus-host disease.
research Randomized Split-Side Study Comparing Efficacy of Botulinum Toxin Type A Versus 0.9% Sodium Chloride in Scalp Psoriasis
Botulinum toxin type A significantly reduces scalp psoriasis severity compared to placebo.
research Phosphodiesterase (PDE) Inhibitors for the Treatment of Inflammatory Skin Conditions
PDE inhibitors, especially PDE4 inhibitors like apremilast, are effective for certain inflammatory skin conditions but have side effects and can be costly.
research Building and Crossing the Translational Bridge: 2016 Alopecia Areata Research Summit Highlights
The summit aimed to speed up finding treatments for alopecia areata.
research Stem Cells in the Body
Stem cells regenerate tissues and their behavior varies by environment, suggesting the hematopoietic system model may need revision.
research Homeostatic Activation of Epidermal HSD11b1 Affects Skin Innervation and Non-Histaminergic Itch
HSD11b1 affects skin nerves and increases non-histaminergic itch.
research Cutaneous Lupus Erythematosus: Overview and Treatment
The document concludes that Cutaneous Lupus Erythematosus has different forms, is influenced by genetic and environmental factors, and can be treated with various medications, but more targeted therapies are needed.
research Tafluprost, a Prostaglandin F2α Analog, Has Therapeutic Potential for Androgenic Alopecia through Modulation of Hair Cycle
Tafluprost could be a potential treatment for hair loss by promoting hair growth phase changes.
research Preoperative Versus Postoperative Language Specialization in Infants with Sagittal Craniosynostosis: An ERP Study
Surgery may help infants with sagittal craniosynostosis develop more typical language processing.
research An Immune Regulatory CCT Repeat Containing Oligodeoxynucleotide Capable of Causing Hair Loss in Male Mice
A specific DNA sequence caused hair loss in male mice by activating immune cells and increasing a certain immune signal.
research Skin Regeneration: Strategies and Innovations
New materials and methods could improve skin healing and reduce scarring.
research Perifollicular Vascularization: Cocultures and Tricultures Approaches to Study the Cross-Talk Between Microvascular Endothelial Cells, Follicle Papilla Cells, and Keratinocytes
Hair papilla cells are crucial for blood vessel development in hair follicles, affecting hair growth and loss.
research Cicatricial Alopecia: What's New in Etiology?
Cicatricial alopecia, a permanent hair loss condition, is mainly caused by damage to specific hair follicle stem cells and abnormal immune responses, with gene regulator PPAR-y and lipid metabolism disorders playing significant roles.
research Hair, Cutaneous Homeostasis, and Stem Cell Functions
Proteins like aPKC and PDGF-AA, substances like adenosine and ATP, and adipose-derived stem cells all play important roles in hair growth and health, and could potentially be used to treat hair loss and skin conditions.
research Introduction to Innovations in the Immunology and Clinical Science of Alopecia Areata
New research is helping develop better treatments for alopecia areata.
research Alopecia Areata: Probing the Deforestation
The document concludes that doctors should recognize congenital triangular alopecia to avoid unnecessary treatments, as it does not respond to steroids like alopecia areata does.
research Wound Healing, Cutaneous Therapy, Hair
Certain hairstyles can cause scalp diseases, smoking is linked to hair loss, 5% minoxidil foam is effective for hair loss treatment, and various factors influence wound healing and hair growth.
research Molecular Regulation and Cellular Heterogeneity in Skin Repair and Hair Follicle Regeneration
Ovol2 is crucial for hair growth and skin healing by controlling cell movement and growth.
research The Efficacy of 1550-nm Erbium-Glass Fractional Laser Treatment and Its Effect on the Expression of Insulin-Like Growth Factor 1 and Wnt/β-Catenin in Androgenetic Alopecia
Finasteride helps female-pattern hair loss.
research The Influence of a Biofilm-Dispersing Wound Gel on the Wound Healing Process
The biofilm-dispersing wound gel helps wounds heal faster and prevents infection.
research Lichen Planopilaris Is Characterized By Immune Privilege Collapse Of The Hair Follicle's Epithelial Stem Cell Niche
Lichen planopilaris may be an autoimmune disease causing hair loss due to immune system issues in hair follicles.
research Overview of Alopecia Areata
Alopecia areata is a genetic and immune-related hair loss condition that is often associated with other autoimmune diseases and does not typically cause permanent damage to hair follicles.
research PD-1+ CXCR5− CD4+ T Cells Are Correlated with the Severity of Systemic Lupus Erythematosus
Tph cells are linked to the severity of systemic lupus erythematosus.
research Pro-Inflammatory Vδ1+ T-Cells Infiltrates Are Present In And Around The Hair Bulbs Of Non-Lesional And Lesional Alopecia Areata Hair Follicles
Targeting Vδ1+T-cells may help treat alopecia areata.
research Laser Capture Microdissection Reveals Transcriptional Abnormalities In Alopecia Areata Before, During, And After Active Hair Loss
Alopecia areata involves persistent gene abnormalities and immune activity, even in regrown hair, suggesting a risk of relapse.
research Mesenchymal Stem Cells Antagonize IFN-Induced Proinflammatory Changes and Growth Inhibition Effects via Wnt/β-Catenin and JAK/STAT Pathway in Human Outer Root Sheath Cells and Hair Follicles
Mesenchymal stem cells may help treat hair loss by improving hair cell growth and reducing inflammation.
research Birth, Life, and Death of the MAGE3 Hypothesis of Alopecia Areata Pathobiology
The MAGE3 hypothesis for alopecia areata did not lead to a significant breakthrough.
research Dietary Habits in Japanese Patients with Alopecia Areata
Japanese patients with alopecia areata often have a higher BMI and consume more vitamin C, fruit, and retinol, which may affect their condition's development or severity.