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The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

PCOS is common among Chinese women of reproductive age and linked to serious metabolic and reproductive issues, especially in obese women.

The NAMS 2014 recommendations guide healthcare providers on treating health issues in midlife women, emphasizing individualized care and informed decision-making.

Metformin helps manage polycystic ovary syndrome by improving insulin resistance and ovulation, but more research is needed on its full effects.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Hair loss needs more research for better treatments.

Women with PCOS have a higher risk of diabetes and heart problems, especially when they get older.

Low doses of some substances can be beneficial, while high doses can be harmful or toxic.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Lampreys have a functional vitamin D receptor that may help detoxify harmful substances.

Hormones like estrogen, testosterone, progesterone, and prolactin play complex roles in female sexual function, with testosterone potentially improving sexual desire, arousal, and satisfaction. However, more research is needed to establish safe and effective hormone treatments for female sexual dysfunction.

Lower SHBG levels may increase the risk of PCOS.

Women with PCOS may take longer to get pregnant but can have a normal family size, and should manage their overall health to reduce long-term health risks.

Skin problems in COVID-19 patients are rare and may be due to the body's complex immune response or blood clotting issues.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Researchers found 63 genes linked to male-pattern baldness, which could help in understanding its biology and developing new treatments.

PCOS symptoms change with age; younger women have higher androgen levels and less metabolic issues, while older women face more metabolic challenges despite milder PCOS symptoms.

Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.

SHBG may be a useful early indicator and treatment target for PCOS.

Genetically modified plants could be an important source of omega-3 fats to meet global needs.

The document concludes that future heart disease research should account for sex-specific differences to improve diagnosis, treatment, and outcomes.

Hair diversity is influenced by complex genetics and environmental factors, requiring more research for practical solutions.

Stress from being transgender is linked to higher blood pressure at night and more inflammation, which may affect heart health.

Safflower (Carthamus tinctorius) extract helps hair grow and could be used in hair products.

Female hair loss linked to metabolic syndrome, not in males.