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Estrogens generally inhibit hair growth and improve skin quality, but their exact effects on hair follicles are complex and not fully understood.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

Leptin helps start the growth phase of hair.

Faulty inflammasome activation may lead to autoimmune skin diseases and could be a target for new treatments.

Oxytocin receptors are found in skin cells near touch and pain neurons.

Gender affects hair and scalp characteristics, with differences in hormone responses, graying patterns, and trace metals.

Balding scalps show different gene expressions affecting hair growth compared to non-balding scalps.

SOX4 is crucial for the development of melanoma.

JAK inhibitors may help treat alopecia areata by reversing hair loss.

The conclusion suggests a new treatment for infantile hemangiomas and a potential target for hair loss treatment.

Some medications can improve skin conditions, while lifestyle factors like smoking and drinking may worsen them; treatments like monoclonal antibodies and imiquimod cream show promise for certain skin diseases.

Certain drugs can cause skin lupus, but stopping the drug usually helps. Vaccines work against smallpox, genital herpes, and a type of human papillomavirus. More frequent light therapy clears psoriasis faster. Certain treatments work for psoriasis and dermatitis. A specific cream effectively treats a type of skin cancer. Low iron levels aren't directly linked to chronic hair loss.

Calreticulin has roles in healing, immune response, and disease beyond its known functions in the endoplasmic reticulum.

Melatonin is important for skin health and protection, and can be made by the skin or applied to it.

Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.

Androgens can cause hair growth in some areas and hair loss on the scalp.

Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.

Estrogen replacement can improve skin health in menopausal women but doesn't reverse sun damage or prevent hair loss.

Melatonin helps regulate hair growth and protects the hair follicle from stress.

The sebaceous gland has more roles than just producing sebum and contributing to acne, and new research could lead to better skin disease treatments.

The document concludes that accurate diagnosis and personalized treatment are important for skin problems in women with PCOS.

Sensitive skin is often caused by nerve fibers and environmental factors, and can be managed with mild skincare and professional advice.

Methotrexate is a key, cost-effective drug for skin conditions, but requires careful monitoring for side effects.

Human hair follicles produce and respond to erythropoietin, helping protect against stress.

Short-chain fatty acids from *Cutibacterium acnes* cause skin inflammation, contributing to acne.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Wound healing insights can improve regenerative medicine.

Epidermal stem cells could lead to new treatments for skin and hair disorders.

Certain signals and genes play a key role in hair growth and regeneration, and understanding these could lead to new treatments for skin regeneration.

Alefacept may effectively treat severe lichen planus, with patients showing significant improvement and no side effects.