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This study found that patients with the MITF p.E318K variant are more likely to develop multiple primary melanomas and dysplastic nevi with uncommon dermoscopic patterns compared to non-carriers.

This study found that patients with myotonic dystrophy type 1 had higher numbers of nevi, dysplastic nevi, melanomas, and pilomatrixomas compared to age- and sex-matched controls.

This study found that men with a cutaneous melanoma diagnosis had an increased risk of subsequently being diagnosed with prostate cancer compared to those without melanoma.

In this study, 37.5% of patients with nodal or metastatic cutaneous melanoma treated with immune checkpoint inhibitors developed skin adverse events, primarily low-grade rashes, vitiligo, and other dermatological symptoms, occurring mainly after 10 weeks of treatment.

This study found that basal cell carcinoma is more prevalent on the cutaneous lip while squamous cell carcinoma is more common on the vermilion lip, with rare recurrences following Mohs micrographic surgery.

This review summarizes common skin-related side effects of BRAF inhibitors and immunotherapy in advanced melanoma treatment, reporting no new clinical findings, and emphasizes consensus management to improve patient outcomes.

In this study, only European-ancestry females showed a linear increase in cutaneous malignant melanoma risk with age, potentially due to the loss of HPV-infected androgenic follicles after menopause.

This study observed that scalp melanomas had worse outcomes than non-scalp head and neck melanomas, with a higher risk of recurrence and melanoma-specific death.

This study found that an ML model incorporating factors like Breslow thickness and age improved cutaneous malignant melanoma prognosis predictions compared to TNM staging, with a C-index of 80% versus 66.6% for TNM alone, suggesting ML's potential for personalized prognostication.

In this study, encorafenib combined with binimetinib was well tolerated in melanoma patients, resulting in relatively few cutaneous adverse events compared to other BRAF and MEK inhibitors.

This study found that 87% of patients with stage IIA and IIB melanoma treated with low-dose alpha-interferon reported cutaneous side effects, with the most common being hair loss.

In this study, multiple cutaneous adverse effects were observed in patients with metastatic malignant melanoma receiving BRAF inhibitors, but most were well managed with appropriate treatment.

This review discusses the cutaneous side effects associated with vemurafenib and ipilimumab in metastatic melanoma treatment and emphasizes the importance of dermatologists in managing these skin eruptions; it reports no new clinical results.

This study found that the administration of the mutant BRAF inhibitor dabrafenib in patients with metastatic melanoma was associated with various skin lesions, including keratinocytic proliferation that sometimes showed low-grade malignancy features.

This study found that in thin cutaneous melanomas, tumor regression is associated with a higher risk of sentinel lymph node involvement.

This study revealed that during fetal development, MITF and Mart-1 expressing melanocytes progress from the dermis to the epidermis and hair follicles, with MITF possibly marking follicular stem cells.

This study found that inhibiting the Hedgehog pathway may reduce proliferation and migration in melanoma, suggesting its potential repurposing as a therapeutic target.

This study found that adding cell adhesion-linked gene expression variables improved the identification of patients with SLN metastases within 90 days of melanoma diagnosis compared to using clinicopathologic variables alone.

Finding a positive nonsentinel lymph node in melanoma patients indicates a worse prognosis.

Finasteride use for hair loss is linked to an increased risk of suicidal thoughts and a higher risk of suicide.

This review concludes that exogenous hydrogen peroxide, rather than UV light, is likely the key factor in the development of cutaneous melanoma in swimmers, as it can penetrate water-submerged hair follicles.

This manuscript suggests that exogenous hydrogen peroxide is a primary risk factor for higher incidence of cutaneous melanoma in swimmers, with UV radiation playing a secondary role.

This paper explores the relationship between the dermal extracellular matrix and cutaneous malignant melanoma, suggesting that ECM involvement may play a key role in the cancer's growth, invasiveness, and initial metastasis.

An 86-year-old man had a rare tongue melanoma but refused treatment, showing the need for early cancer detection and treatment.

In this prospective study, dabrafenib and trametinib were associated with various skin side effects, including papillomas, hyperkeratosis, and acneiform eruptions in patients with metastatic melanoma.

This study found that in mutant NRAS melanoma, MEK inhibitors led to increased AKT signaling and reduced MIG6, a change that may enhance cell migration and invasiveness.

This review discusses skin-related adverse effects from targeted cancer therapies in dermatology but does not provide new clinical results, emphasizing the essential role of dermatologists in managing these toxicities.

This abstract outlines the current understanding of cutaneous squamous cell carcinoma (cSCC), identifying it as the second most common non-melanoma skin cancer with risk factors like UV exposure and immunosuppression. It highlights cSCC's potential to metastasize and become fatal, affecting 2%-5% of in situ cases.

Vascular patterns in dermoscopy help tell apart malignant and benign skin tumors.

This study found that bone marrow-derived epithelial cells were abundantly recruited to some skin tumors in mice, indicating a systemic contribution to cutaneous neoplasms.