June 2023 in “British Journal of Dermatology” Coinheritance of BRCA2 and CYLD genes may lead to new treatment options for certain cancers.
January 2018 in “Elsevier eBooks” Minoxidil helps lower severe blood pressure and promotes hair growth but can have serious side effects and must be used continuously.
187 citations,
December 2005 in “Experimental Dermatology” Estrogens can improve skin aging but carry risks; more research is needed on safer treatments.
26 citations,
October 2016 in “Clinics in Dermatology” Hormonal treatments can improve acne, but they come with potential side effects and risks.
224 citations,
March 2006 in “Seminars in Cutaneous Medicine and Surgery” The document concludes that understanding hair follicle biology can lead to better hair loss treatments.
June 2019 in “International journal of dermatology and venereology” A man developed skin issues from cancer medication, which improved with specific treatments.
July 1975 in “Archives of Dermatology” The document suggests a possible connection between rapid weight loss and hair loss, and reports a case of skin condition improvement after stopping acne medication.
95 citations,
July 2010 in “Genes & development” Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.
71 citations,
February 2020 in “Journal of Translational Medicine” Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.
9 citations,
January 2005 in “Experimental dermatology” Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.
2 citations,
March 2021 in “Molecular Immunology” Dermal macrophages might help regrow hair.
December 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” AP-2α and AP-2β proteins are essential for healthy adult skin and hair.
166 citations,
October 2018 in “Endocrine Reviews” Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.
84 citations,
July 2003 in “European journal of biochemistry” Mouse skin can produce and process serotonin, with variations depending on hair cycle, body location, and mouse strain.
29 citations,
May 2020 in “npj Regenerative Medicine” Immune cells help regulate hair growth, and better understanding this can improve hair loss treatments.
28 citations,
September 2013 in “Expert Opinion on Therapeutic Patents” New resveratrol-related compounds show promise for treating various health issues but need more research for clinical use.
27 citations,
August 2006 in “Laboratory Investigation” SCF and ET-1 together significantly increase skin pigmentation and melanin production.
23 citations,
March 2019 in “The journal of investigative dermatology/Journal of investigative dermatology” ATP increases melanin production in skin after UV exposure, with the P2X7 receptor being crucial for this process.
7 citations,
December 2014 in “Journal of dermatology” Hair shaft miR-221 levels can help detect malignant melanoma.
4 citations,
September 2014 in “Elsevier eBooks” Use some skin medications with caution during pregnancy; avoid strong steroids, certain eczema treatments, and systemic retinoids, but many topical treatments and nasal sprays are safe.
3 citations,
June 2006 in “Expert Review of Dermatology” The document concludes that hair loss is complex, affects many people, has limited treatments, and requires more research on its causes and psychological impact.
February 2024 in “International Journal For Multidisciplinary Research” Nanostructured lipid carriers are effective for treating hyperpigmentation in women aged 30-40.
253 citations,
March 1994 in “Developmental dynamics” Apoptosis is essential for human skin development and forming a functional epidermis.
222 citations,
January 2005 in “Endocrine journal” Melatonin is important for skin health and protection, and can be made by the skin or applied to it.
66 citations,
July 2015 in “Journal of Molecular Biology” The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.
53 citations,
January 2017 in “Skin appendage disorders” Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.
50 citations,
March 2000 in “American Journal of Clinical Dermatology” Alopecia Areata has no guaranteed treatment for hair regrowth, but options like corticosteroids and minoxidil are used, with future research focusing on genetic and immune therapies.
49 citations,
November 1992 in “Archives of dermatology” Different treatments for alopecia areata have varying success rates and side effects; intralesional steroids are most effective.
47 citations,
August 2000 in “Endocrine Reviews” The document concludes that more research is needed to understand excessive hair growth in women with normal hormone levels and regular ovulation.
43 citations,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” The article concludes that advancements in hair cosmetics require dermatologists to stay informed about products and their potential risks, including allergies and higher risks for hairdressers.