9 citations
,
April 2019 in “International Journal of Molecular Sciences” This research indicates that KCED-1 and KCED-2 effectively induce adiponectin production in human subcutaneous fat, which may promote hair growth on the scalp.
9 citations
,
February 2020 in “Journal of Cosmetic Dermatology” In this study, CRH receptor antagonists from Pulsatilla chinensis reversed stress hormone-induced changes in hair follicles and dermal papilla cells in a lab setting, suggesting potential pharmaceutical and cosmetic applications for treating stress-related hair loss.
May 2025 in “Journal of Inflammation Research” In this case report, a 28-year-old Chinese man with severe dissecting cellulitis of the scalp experienced nodules resolution and hair regrowth after treatment with ixekizumab and tofacitinib, marking the first reported use of this drug combination for the condition.
January 2019 in “Publisher” This study found that human basal cell and squamous cell carcinomas have distinct gene expression patterns, with specific up-regulation of zinc finger encoding genes in basal cell carcinoma.
18 citations
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December 2016 in “Phytomedicine” In this study, applying 1% or 5% Curcuma aeruginosa essential oil lotion to the underarm for 10 weeks significantly slowed hair growth and brightened skin in young women, with no adverse effects reported.
26 citations
,
April 1996 in “Journal of Investigative Dermatology”
This case study presented by the researchers describes the effective use of topical calcipotriene ointment in treating a 6-year-old girl with en coup de sabre scleroderma, resulting in normalization of the sclerotic skin, hair regrowth, and improved pigmentation.
41 citations
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August 2015 in “The FASEB Journal” The researchers reported that topical application of small-molecule Wnt inhibitors significantly reduced fibrosis and promoted regenerative wound healing in mice.
December 2024 in “European journal of medical research” This study suggests that the NCSTN knockout mouse could serve as an HS animal model, with tamoxifen potentially used for gene deletion in mice.
April 2024 in “Materials today bio” In this study, the researchers developed a novel wound dressing incorporating copper-doped calcium silicate and curcumin, which significantly promoted nerve and blood vessel regeneration in deep burn wounds, emphasizing the crucial role of bioactive chelation in neuralized skin repair.
118 citations
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August 2010 in “Developmental Cell” This study found that the protein MIM is crucial for maintaining cilia and Sonic hedgehog signaling in mesenchymal cells by counteracting Src-mediated phosphorylation of Cortactin, impacting hair follicle formation.
10 citations
,
July 1980 in “British Journal of Dermatology” This study observed that applying polyamines to the skin of hairless mice stimulates thymidine incorporation, suggesting polyamines may play a role in DNA synthesis control in the epidermis.
July 2024 in “Journal of Investigative Dermatology” Substance P helps restore skin thickness and cell renewal when sensory nerves are reduced.
July 2021 in “Asia-Pacific journal of convergent research interchange” This research on dermal papilla cells found that Sparasis crispa increased mRNA expression related to hair production and may help in hair generation cycles, but its impact on male hair loss treatment remains uncertain.
October 2025 in “Frontiers in Veterinary Science” This study found that treating secondary hair follicle stem cells from Arbas cashmere goats with 10 μg/mL quercetin for 48 hours significantly boosted cell proliferation and reduced apoptosis by activating several signaling pathways, suggesting a potential strategy to enhance cashmere production.
August 2002 in “British journal of ophthalmology” This article reports that while surgical excision is often the best treatment for SCC, intralesional cidofovir also showed success without systemic toxicity in the case discussed.
November 2024 in “Journal of Investigative Dermatology” 8 citations
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February 2025 in “Cell Systems” This study developed a genetic toolbox to engineer Cutibacterium acnes for dermal applications, successfully creating a strain that secretes antioxidants to reduce oxidative stress in a UV stress model.
4 citations
,
July 2012 in “Genesis” This study reported that a Megsin-Cre transgene enables genetic manipulation primarily in skin, forestomach, and esophagus tissues, offering a new tool for studying development and diseases in these areas.
January 1998 in “Differentiation” Basonuclin is crucial for hair follicle development and cycling in mice.
1 citations
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October 2025 in “Current Issues in Molecular Biology” This research found that escin, when applied topically, enhances blood flow in human skin and promotes changes in endothelial cell signaling pathways, suggesting potential benefits for improving cutaneous microcirculation.
December 2021 in “Journal of natural fibers” In this study, researchers developed enzymatic methods to isolate hair cuticle cells and remove the hair cuticle layer, finding that the harvested cuticle cells are thermally more stable and contain different structural proteins compared to descaled hair fibers.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” This study observed that mice lacking epidermal HSD11b1 had increased non-histaminergic itch and changes in skin nerve fibers, potentially linked to higher TSLP expression.
25 citations
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September 2020 in “Molecules” In this study, quercitrin was reported to promote hair growth and cell viability in cultured human dermal papilla cells by enhancing cellular energy metabolism and growth factor production via MAPK/CREB signaling.
27 citations
,
October 1998 in “Differentiation” Basonuclin helps identify and track hair follicle development and cycling in mice.
26 citations
,
October 1997 in “Planta Medica” This study found that bisbenzylisoquinoline alkaloids from Stephania cepharantha Hayata stimulated growth in cultured murine hair cells but not in keratinocytes or fibroblasts.
7 citations
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September 2014 in “Beni-Suef University Journal of Basic and Applied Sciences” This study found that ethanolic and petroleum ether extracts of Cuscuta reflexa, as well as an isolate from these extracts, improved hair growth and follicle characteristics in androgen-induced alopecia in rats.
44 citations
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March 2012 in “Fitoterapia” In this study, germacrone from Curcuma aeruginosa showed anti-androgenic effects by inhibiting 5α-reductase, suggesting its potential as a lead compound for treating androgen-dependent disorders.
June 2025 in “Healthy-Mu Journal” The optimized Cinchonine gel effectively fights acne bacteria and is safe for twice-daily use.
16 citations
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June 2015 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that DHHC13 is crucial for hair anchoring and skin barrier function, with its deficiency in Zdhhc13(skc4) mice leading to cyclic alopecia and skin abnormalities due to cornifelin deficiencies.